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Monopar Announces ALXN1840 Data Selected for Late-Breaker Presentation at EASL Congress 2025

Key Takeaway: Monopar Therapeutics Inc. announced that data on its drug candidate ALXN1840 for Wilson disease has been accepted for a late-breaker poster presentation at the EASL International Liver Congress 2025. This prestigious event is set to be held in Amsterdam from May 7 to May 10, 2025. The late-breaker presentation is significant, as it highlights recent advancements and potentially impactful findings in the field. The presentation will be delivered by Dr. Karl Heinz Weiss and will focus on the sustained long-term clinical improvement of Wilson disease patients treated with tiomolybdate choline.
Price reaction · baseline $40.81 (2025-04-28 close) · hit after-hours · clean, no other MNPR news in the window
day 0 close · peak
+2.8%

Market Sentiment Analysis

POSITIVE FACTORS

  • ALXN1840 data accepted for late-breaker presentation, indicating scientific significance.
  • Opportunity to present at a prestigious event, EASL Congress 2025.
  • Potential for significant clinical impact on Wilson disease treatment.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+140%
120-day peak, hindsight
Typical move
5.5%
average across 4 past catalysts
Cash runway
~97 mo
Minimal dilution risk
Lead asset
MNPR-101-PCTA-177Lu
Phase 1 · Solid Tumor, Adult

Full Press Release Details

WILMETTE, Ill., April 29, 2025 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company focused on developing innovative treatments for patients with unmet medical needs, today announced that data on the long term efficacy and safety of its ALXN1840 (tiomolybdate choline) drug candidate for Wilson disease has been accepted for a late-breaker poster presentation at the European Association for the Study of the Liver (“EASL”) International Liver Congress 2025. EASL is recognized as one of the premier events in the hepatology space and will be held in Amsterdam, Netherlands from May 7 – 10, 2025.
Late-breaker provides an opportunity to present “the most recent and significant findings,” according to EASL. Criteria for late-breaker abstracts include: (1) they present the latest, up-to-date research findings; (2) the research is considered highly significant with the potential to impact the field in a substantial manner; and (3) clinical studies should be prospective. Late-breaker abstracts undergo a rigorous review, and the acceptance rate is lower than regular abstracts with only the most compelling abstracts selected.
Details of the EASL Congress 2025 late-breaker poster presentation are as follows:
Title: Sustained long-term clinical improvement in Wilson disease patients on tiomolybdate choline
Abstract Number: LB25251
Session: Late-breaker Posters
Date and Time: Wednesday, May 7, 8:30 a.m. CET
Presenter: Karl Heinz Weiss, M.D.
Location: Amsterdam, Netherlands
The poster to be presented at EASL 2025 will be available online at www.monopartx.com on May 7, 2025.
About Monopar Therapeutics Inc.
Monopar Therapeutics is a clinical-stage biotechnology company with late-stage ALXN1840 for Wilson disease, and radiopharma programs including Phase 1-stage MNPR-101-Zr for imaging advanced cancers, and Phase 1a-stage MNPR-101-Lu and late preclinical-stage MNPR-101-Ac225 for the treatment of advanced cancers. For more information, visit: www.monopartx.com.
Monopar Therapeutics Inc.
Chief Financial Officer
Follow Monopar on social media for updates:
X: @MonoparTx  LinkedIn: Monopar Therapeutics

Frequently Asked Questions

What is the focus of Monopar Therapeutics?

Monopar Therapeutics specializes in developing innovative treatments for unmet medical needs.

When is the EASL International Liver Congress 2025?

The congress takes place from May 7 to May 10, 2025, in Amsterdam.

What will be presented at EASL regarding tiomolybdate choline?

Data on the long-term efficacy and safety of tiomolybdate choline for Wilson disease.

Who will present the poster at EASL 2025?

The poster will be presented by Karl Heinz Weiss, M.D.

Where can I find the EASL poster online?

The poster will be available at www.monopartx.com on May 7, 2025.

Last updated: Apr 29, 2025