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MIRA Pharmaceuticals’ Second Ketamir-2 Manuscript Accepted for Peer-Reviewed Publication Demonstrating Superior Efficacy in Preclinical Neuropathic Pain Models Versus Ketamine, Gabapentin, or Pregabalin

Key Takeaway: MIRA Pharmaceuticals has announced that its manuscript detailing the efficacy of Ketamir-2 has been accepted for publication in Frontiers in Pharmacology. The study demonstrates that Ketamir-2 outperforms ketamine, gabapentin, and pregabalin in preclinical neuropathic pain models. This finding supports the company's plans to advance Ketamir-2 to Phase 2a clinical trials by the end of 2025.
Price reaction · baseline $1.42 (2025-08-11 close) · hit pre-market · clean, no other MIRA news in the window
day 0 close · peak
+3.5%

Market Sentiment Analysis

POSITIVE FACTORS

  • Ketamir-2 shows superior efficacy in neuropathic pain models.
  • Manuscript accepted for publication in a reputable journal.
  • Advancement to Phase 2a clinical trials is planned by 2025.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+5%
120-day peak, hindsight
Typical move
0.6%
average across 2 past catalysts
Cash runway
~21 mo
Low dilution risk

Full Press Release Details

Manuscript accepted for publication in Frontiers in Pharmacology, “Oral Administration of Ketamir-2, a Novel Ketamine Analog, Attenuates Neuropathic Pain in Rodent Models via Selective NMDA Antagonism” details Ketamir-2’s superior performance in two validated neuropathic pain models and supports advancement to Phase 2a clinical trials by year-end 2025. MIAMI, FL / ACCESS Newswire / August 12, 2025 / MIRA Pharmaceuticals, Inc. (NASDAQ:MIRA) (“MIRA” or the “Company”), a clinical-stage p…
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Frequently Asked Questions

What is Ketamir-2?

Ketamir-2 is a novel ketamine analog developed by MIRA Pharmaceuticals.

What did the manuscript demonstrate?

The manuscript showed that Ketamir-2 is more effective than ketamine, gabapentin, and pregabalin in neuropathic pain models.

Where was the manuscript published?

It was accepted for publication in Frontiers in Pharmacology.

When will Ketamir-2 enter clinical trials?

MIRA plans to advance Ketamir-2 to Phase 2a clinical trials by the end of 2025.

Last updated: Aug 12, 2025