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Rule 4.7B Appendix 4C Quarterly report for entities subject to Listing Rule 4.7B Introduced 31/03/00 Amended 30/09/01, 24/10/05, 17/12/10, 01/09/16 Name of entity Mesoblast Limited ABN Quarter ended ("current quarter") 6

Key Takeaway: Quarterly report for entities subject to Listing Rule 4.7B Introduced 31/03/00 Amended 30/09/01, 24/10/05, 17/12/10, 01/09/16 Consolidated statement of cash flows Current quarter Year to date (6 months) US$ '000 US$ '000 1 Cash flows from operating activities

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Quarterly report for entities subject to Listing Rule 4.7B
Introduced 31/03/00 Amended 30/09/01, 24/10/05, 17/12/10, 01/09/16
Consolidated statement of cash flows
Current quarter Year to date (6 months)
US$ '000 US$ '000
1 Cash flows from operating activities
1.1 Receipts from customers 26,915 28,510
1.2 Payments for:
(a) research and development (14,179 ) (26,818 )
- includes the costs of the three Tier 1 Phase 3 programs in advanced chronic heart failure, chronic low back pain and acute graft vs host disease.
(b) manufacturing commercialisation (2,951 ) (6,843 )
(c) advertising and marketing - -
(d) leased assets - -
(e) staff costs (3,462 ) (5,589 )
(f) other expenses from ordinary activities (3,067 ) (5,914 )
(g) other:
- intellectual property portfolio expenses (488 ) (1,022 )
1.3 Dividends received (see note 3) - -
1.4 Interest received 157 293
1.5 Interest and other costs of finance paid (896 ) (1,783 )
1.6 Income taxes paid - (3 )
1.7 Government grants and tax incentives - 1,654
1.8 Other provide details if material) - -
1.9 Net cash from / (used in) operating activities 2,029 (17,515 )
Quarterly report for entities subject to Listing Rule 4.7B
Current quarter Year to date (6 months)
US$ '000 US$ '000
2 Cash flows from investing activities
2.1 Payment to acquire:
(a) property, plant and equipment (73 ) (112 )
(b) businesses (see item 10) - -
(c) investments - -
(d) intellectual property - -
(e) other non-current assets - -
2.2 Proceeds from disposal of:
(a) property, plant and equipment - -
(b) businesses (see item 10) - -
(c) investments - -
(d) intellectual property - -
(e) other non-current assets - -
2.3 Cash flows from loans to other entities - -
2.4 Dividends received (see note 3) - -
2.5 Other (provide details if material) - -
(a) Payments for contingent consideration - -
2.6 Net cash from / (used in) investing activities (73 ) (112 )
Current quarter Year to date (6 months)
US$ '000 US$ '000
3 Cash flows related to financing activities
3.1 Proceeds from issues of shares 20,000 30,000
3.2 Proceeds from issue of convertible notes - -
3.3 Proceeds from exercise of share options 210 258
3.4 Transaction costs related to issues of shares, convertible notes or options (250 ) (608 )
3.5 Proceeds from borrowings - 28,950
3.6 Repayment of borrowings - -
3.7 Transaction costs related to loans and borrowings (11 ) (1,545 )
3.8 Dividends paid - -
3.9 Other (provide details if material) - -
3.10 Net cash from / (used in) financing activities 19,949 57,055
Current quarter Year to date (6 months)
US$ '000 US$ '000
4 Net increase / (decrease) in cash and cash equivalents for the period
4.1 Cash and cash equivalents at beginning of quarter/year to date 55,143 37,763
4.2 Net cash from / (used in) operating activities (item 1.9 above) 2,029 (17,515 )
4.3 Net cash from / (used in) investing activities (item 2.6 above) (73 ) (112 )
4.4 Net cash from / (used in) financing activities (item 3.10 above) 19,949 57,055
4.5 Effect of movement in exchange rates on cash held (26 ) (169 )
4.6 Cash and cash equivalents at end of quarter 77,022* 77,022*
* Additionally US$15.0 million in gross cash proceeds were received from Hercules Capital on January 11, 2019 pursuant to a Loan and Security Agreement entered into on March 6, 2018.
+ See chapter 19 for defined terms.
01/09/2016 Appendix 4C Page 2
Quarterly report for entities subject to Listing Rule 4.7B
Current quarter Previous quarter
US$ '000 US$ '000
5 Reconciliation of cash and cash equivalents
at the end of the quarter (as shown in the consolidated statement of cash flows) to the related items in the accounts
5.1 Bank balances 76,598 54,611
5.2 Call deposits - 99
5.3 Bank overdrafts - -
5.4 Other (Term deposits) 424 433
5.5 Cash and cash equivalents at end of quarter (should equal item 4.6 above) 77,022* 55,143
* Additionally US$15.0 million in gross cash proceeds were received from Hercules Capital on January 11, 2019 pursuant to a Loan and Security Agreement entered into on March 6, 2018.
Current quarter
US$ '000
6 Payments to directors of the entity and their associates
6.1 Aggregate amount of payments to these parties included in item 1.2 390
6.2 Aggregate amount of cash flow from loans to these parties included in item 2.3 -
6.3 Include below any explanation necessary to understand the transactions included in items 6.1 and 6.2
Payment to directors (for the current quarter) = $390,000
Current quarter
US$ '000
7 Payments to related entities of the entity and their associates
7.1 Aggregate amount of payments to these parties included in item 1.2 -
7.2 Aggregate amount of cash flow from loans to these parties included in item 2.3 -
7.3 Include below any explanation necessary to understand the transactions included in items 7.1 and 7.2
not applicable
+ See chapter 19 for defined terms.
01/09/2016Appendix 4C Page 3
Quarterly report for entities subject to Listing Rule 4.7B
Total facility amount at quarter end Amount drawn at quarter end
US$ '000 US$ '000
8 Financing facilities available
Add notes as necessary for an understanding of the position
8.1 Loan facilities 115,000* 65,000*
8.2 Credit standby arrangements - -
8.3 Other (please specify) - -
8.4 Include below a description of each facility above, including the lender, interest rate and whether it is secured or unsecured. If any additional facilities have been entered into or are proposed to be entered into after quarter end, include details of those facilities as well.
*Loan facility with Hercules Capital, Inc. On March 6, 2018, Mesoblast entered into a Loan and Security Agreement with Hercules Capital, Inc. ("Hercules Capital") for a US$75.0 million secured four-year credit facility. Mesoblast drew the first tranche of US$35.0 million on closing. An additional US$15.0 million was drawn during Q1 CY2019, and a further US$25.0 million may be drawn on or before Q4 CY2019, as certain milestones are met. On December 20, 2018, in line with the increase in the U.S. prime rate, the interest rate on the loan increased to 10.45%. *Loan facility with NovaQuest Capital Management, L.L.C. On June 29, 2018, Mesoblast entered into a Loan and Security Agreement with NovaQuest Capital Management, L.L.C. ("NovaQuest") for a non-dilutive US$40.0 million secured eight-year term loan. Mesoblast drew the first tranche of US$30.0 million of the loan on closing. An additional US$10.0 million from the loan will be drawn on marketing approval of remestemcel-L by the United States Food and Drug Administration (FDA). Prior to maturity in July 2026, the loan is only repayable from net sales of remestemcel-L (MSC-100-IV) in the treatment of pediatric patients who have failed to respond to steroid treatment for acute Graft versus Host Disease (aGvHD), in the United States and other geographies excluding Asia. Interest on the loan will accrue at a rate of 15% per annum with the interest only period lasting 4 years. Interest payments will be deferred until after the first commercial sale. The financing is subordinated to the senior creditor, Hercules Capital.
US$ '000
9 Estimated cash outflows for next quarter
9.1 Research and development (12,704 )
9.2 Manufacturing commercialisation (3,075 )
9.3 Advertising and marketing -
9.4 Leased assets -
9.5 Staff costs (1,889 )
9.6 Other expenses from ordinary activities (3,268 )
9.7 Other (provide details if material):
(a) Intellectual property portfolio expenses (768 )
(b) Interest expenses (1,180 )
9.8 Total estimated cash outflows (22,884)*
* In the next quarter, Mesoblast's cash and cash equivalents will be augmented by the following cash receipts:
US$15.0 million drawn down from the Loan and Security Agreement with Hercules;
royalty receipts earned on sales of TEMCELL HS Inj. 1 in Japan; and
interest income receipts.
+ See chapter 19 for defined terms.
01/09/2016 Appendix 4C Page 4
Quarterly report for entities subject to Listing Rule 4.7B
The company remains in advanced negotiations with a number of potential commercial partners regarding potential transactions and access to non-dilutive capital. Mesoblast does not make any representation or give any assurance that such a partnering transaction will be concluded.
Up to an additional US$35.0 million is available to Mesoblast subject to achievement of certain milestones, under the financing arrangements with Hercules Capital, Inc and NovaQuest. Refer to 8.4 for further details.
Mesoblast established an equity facility in 2016 with Kentgrove Capital for up to A$120.0 million/US$90.0 million over the next 6 months to be used at its discretion to provide additional funds as required.
1 TEMCELL HS. Inj. is a registered trademark of JCR Pharmaceuticals Co. Ltd.
Acquisitions Disposals
US$ '000 US$ '000
10 Acquisitions and disposals of business entities
(items 2.1(b) and 2.2(b) above)
10.1 Name of entity - -
10.2 Place of incorporation or registration - -
10.3 Consideration for acquisition or disposal - -
10.4 Total net assets - -
10.5 Nature of business - -
Compliance statement
Sign here:/s/ Charlie HarrisonDate: 31 January 2019
Print name:Charlie Harrison
+ See chapter 19 for defined terms.
01/09/2016Appendix 4C Page 5
Last updated: Feb 5, 2019