Check-Cap Ltd. Check-Cap Building 29 Abba Hushi Avenue P.O. Box 1271 Isfiya, 3009000 Israel AMENDED NOTICE OF EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS Dear Shareholder: On

29 Abba Hushi Avenue

AMENDED NOTICE OF EXTRAORDINARY GENERAL MEETING

On March 20, 2024, Check-Cap Ltd. ("Check-Cap,"

the "Company," "we," or "our") announced an Extraordinary General Meeting of Shareholders (the "Meeting")

to be held on April 25, 2024 at 9:00 a.m. (Eastern time).

The Company is amending the Notice of Extraordinary

General Meeting of Shareholders, as amended on April 4, 2024 (the "Notice"), to reflect a change in the location of the Meeting.

The Meeting will now be held at:

The Ritz Carlton, Toronto, 181 Wellington Street West, Toronto, Ontario, Canada, M5V 3G7.

No changes have been made to Proposals 1 through

9 set forth in the Proxy Statement, dated as of April 4, 2024 (the "Proxy Statement").

Accordingly, at the Meeting, you will be asked to consider and vote

We are currently not

aware of any other matters that will come before the Meeting. If any other matters are presented properly at the Meeting, the persons

designated as proxies intend to vote upon such matters in accordance with their best judgment.

of record at the close of business on March 25, 2024, are entitled to notice of and to vote at the Meeting or at any adjournment thereof

for Proposal 1 to Proposal 8 and the proxy card received by such shareholders will only include Proposals 1 to 8. Only shareholders

of record at the close of business on April 8, 2024, are entitled to notice of and to vote at the Meeting or at any adjournment thereof

for Proposal 9 and the proxy card received by such shareholders will only include Proposal 9. You can vote either by mailing in your proxy,

by Internet, or in person by attending the Meeting. Proxies must be received by our transfer agent or at our registered office in

Israel no later than four (4) hours prior to the designated time for the Meeting. Proxies received by our transfer agent or at our

registered office in Israel during the four (4) hours preceding the designated time for the Meeting will be presented to the Chairman

of the Meeting and, at his discretion, may be voted as specified in the instructions included in such proxies. If you attend the

Meeting, you may vote in person and your proxy will not be used. If you hold Ordinary Shares through a bank, broker or other nominee

(i.e., in "street name") which is one of our shareholders of record at the close of business on the record date, or which

appears in the participant listing of a securities depository on that date, you must follow the instructions included in the voting instruction

form you receive from your bank, broker or nominee, and may also be able to submit voting instructions to your bank, broker or nominee

by phone or via the Internet. If you hold your Ordinary Shares in "street name" and you wish to vote in person

at the Meeting, you must first obtain a "legal proxy" from your broker, bank, trustee or nominee that holds your shares giving

you the right to vote the shares at the Meeting.

OF DIRECTORS RECOMMENDS THAT YOU VOTE "FOR" PROPOSAL 1 TO PROPOSAL 9.

The presence, in person

or by proxy, of two or more shareholders holding or representing, in the aggregate, at least twenty-five percent (25%) of our company's

voting rights will constitute a quorum at the Meeting. No business will be considered or determined at the Meeting unless the requisite

quorum is present within half an hour from the time designated for the Meeting. If within half an hour from the time designated

for the Meeting a quorum is not present, the Meeting will stand adjourned to the day, time and place as the Chairman of the Meeting shall

determine. At least two shareholders present, in person or by proxy, will constitute a quorum at the adjourned meeting.

Approval of the Proposals

vote is very important, regardless of the number of ordinary shares that you own. Each ordinary share entitles the holder to

1 - CFO Compensation Proposal: The affirmative vote of the holders of a majority of the ordinary shares

represented at the Meeting, in person or by proxy, and entitled to vote and voting on the matter, is required to approve Proposal 1.

2 - CEO Compensation Proposal: The affirmative vote of the holders of a majority of the ordinary shares

represented at the Meeting, in person or by proxy, and entitled to vote and voting on the matter, is required to approve Proposal 2.

4, 5, 6, 7 - Board Ratification and Approval of Appointment Proposals:

The five director nominees to be appointed to the Company's Board (each, a "Director Nominee") shall be voted on separately.

Each Director Nominee shall be elected by the affirmative vote of the holders of the majority of the ordinary shares represented at the

Meeting, in person or by proxy, entitled to vote and voting on the matter.

8 - Board Member Removal Proposal: The affirmative vote of the holders of a majority of the ordinary shares

represented at the Meeting, in person or by proxy, and entitled to vote and voting on the matter, is required to approve Proposal 8.

9 - Engagement of the Independent Auditor Proposal: The affirmative vote of the holders of a majority of

the ordinary shares represented at the Meeting, in person or by proxy, and entitled to vote and voting on the matter, is required to approve

In accordance with the

Israeli Companies Law and regulations promulgated thereunder, any shareholder was permitted to submit to us a position statement on its

behalf, expressing its position on an agenda item for the Meeting to our offices, Check-Cap Building, 29 Abba Hushi Avenue, P.O. Box 1271,

Isfiya, 3009000, Israel, Attention: Paul Medeiros, Chairman of the Board, or by facsimile to +972-4-8211267. The deadline for such submission

was April 15, 2024, at 9:00 a.m.

The Proxy Statement describing the proposals and

the accompanying proxy card have been filed with the U.S. Securities and Exchange Commission (the "SEC") and will be mailed

to shareholders. Shareholders may also review the Proxy Statement as well as the accompanying proxy card, via the website of the SEC at www.sec.gov/edgar and

detailed voting instructions are provided both in the Proxy Statement and the accompanying proxy card.

you have any questions about this Notice or the Meeting or need assistance voting at the Meeting, please contact our proxy solicitor:

+1-212-929-5500(International)

behalf of Check-Cap's Board of Directors, I thank you for your support and appreciate your consideration of these matters.