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Open-label, phase II, multicenter study of lasofoxifene plus abemaciclib for treating women with metastatic ER+/HER2− breast cancer and an ESR1 mutation after disease progression on prior therapies: ELAINE 2

Key Takeaway: The ELAINE 2 study is an open-label, phase II trial investigating the efficacy of lasofoxifene combined with abemaciclib in women with metastatic ER+/HER2- breast cancer who have an ESR1 mutation. This study targets patients who have experienced disease progression after previous therapies. The multicenter design aims to provide comprehensive data on this treatment approach.

Market Sentiment Analysis

POSITIVE FACTORS

  • The study explores a novel treatment combination for a challenging cancer type.
  • Lasofoxifene plus abemaciclib may offer new hope for patients with ESR1 mutations.
  • The multicenter approach enhances the study's reliability and applicability.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~9 mo
Medium dilution risk
Lead asset
ATH-1017
Phase 2 · Alzheimer Disease

Full Press Release Details

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Open-label, phase II, multicenter study of lasofoxifene plus abemaciclib for treating women with metastatic ER+/HER2− breast cancer and an ESR1 mutation after disease progression on prior therapies: ELAINE 2
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Frequently Asked Questions

What is the ELAINE 2 study about?

The ELAINE 2 study investigates lasofoxifene combined with abemaciclib for treating metastatic ER+/HER2- breast cancer.

Who are the participants in the ELAINE 2 study?

Participants include women with metastatic ER+/HER2- breast cancer and an ESR1 mutation after prior therapy failure.

What phase is the ELAINE 2 study?

The ELAINE 2 study is an open-label, phase II clinical trial.

What is the goal of the ELAINE 2 study?

The goal is to evaluate the efficacy of lasofoxifene plus abemaciclib in the specified patient population.

Last updated: Dec 7, 2023