Full Press Release Details
Lexaria Bioscience Announces New Research Including
Cannabinoid Topical Creams and Nicotine Edibles
Kelowna, British Columbia December 15, 2017 Lexaria
Bioscience Corp. (OTCQB: LXRP) (CSE: LXX) (the Company or Lexaria ), a drug
delivery platform innovator, announces a new topical skin cream research and
development ( R&D ) program; R&D into nicotine edibles; and updates
existing R&D programs.
Topical Skin Formulations for Cannabinoids.
has formulated topical cream products as an extension of its DehydraTECH
technology, for the delivery of cannabinoids into and through the skin which may
prove to have emollient benefits desired by the topical products sector.
Lexaria s president, John Docherty M.Sc., has extensive experience as a biotech
company executive and researcher for skin-based delivery of therapeutics.
Multiple Lexaria formulations are scheduled to be laboratory
tested for human skin absorption and penetration characteristics during January
through March 2018. Testing will be completed at a third-party lab utilizing
human skin tissue and the latest in vitro evaluative techniques to
measure cannabidiol penetration in the skin. Lexaria expects to optimize
formulation and manufacturing processes to develop superior-performing product
designs that will potentially be available to licensees during 2018.
Nicotine in Edible Formats.
Lexaria has accelerated
its research focus on nicotine following its recently announced nicotine patent
grant and has been researching edible forms of nicotine which could use the
Company s DehydraTECHTM technology. Formulations have been prepared
and are currently completing quality control testing, prior to in vivo
absorption and tolerability testing in animals.
A third-party Philadelphia based lab has been contracted to
perform the first nicotine edible tests expected in February. In vivo
testing with rats will examine two main outcomes:
distress. Without an enabling technology, untreated nicotine causes
gastrointestinal upset and distress making nicotine edibles impractical. The
DehydraTECHTM process will be evaluated for its ability to lessen
gastrointestinal distress thus potentially opening the door to the creation of a
new line of consumer products.
2) Absorption time and efficiency in crossing
the intestinal wall and reaching the bloodstream. Earlier testing of the
DehyrdaTECHTM process using cannabidiol as an active ingredient, proved reduced absorption times and enhanced
intestinal permeability. It is expected that similar outcomes using nicotine may
University of British Columbia (UBC) TurboCBD Study.
As previously announced, the UBC study was initiated with UBC board
evaluation and approvals. However, a recent change in UBC policy has resulted in
all MITACS/UBC studies of this class to be temporarily halted. This change in
policy affects numerous studies at UBC. Lexaria is currently reviewing methods
of modifying the contemplated UBC study and/or alternatives to complete the
planned study objectives at UBC or elsewhere if necessary and will report on
next steps when they are known.
National Research Council.
The National Research
Council and Lexaria have successfully developed model formulations using the
DehydraTECH process and methodology. Following this completed first phase, the
parties now plan to formulate and test DehydraTECH based cannabinoid
formulations in early 2018 to determine the inherent processes that enable the
palatability and absorption benefits DehydraTECH formulations have
demonstrated. This second phase is expected to be performed with cannabinoids
for the first time to provide additional guidance for further study.
Formulation Experimentation.
Lexaria has conducted
various cannabinoid formulation experiments, together with potential
DehydraTECH licensee partners, on chocolates, candies, gummies, mouth-melts,
chocolate bars, protein bars, beverages such as beer, spices, tea, coffee,
supplements and more.
Beverage formulations have produced cannabinoid water-based
products including de-alcoholized beer that mask unwanted cannabis flavor and
are fast acting. Chocolate formulations were reported as being the fastest
acting, most consistent, and best-tasting products in approximately 70% of cases
in a recent consumer study. As the recreational markets for cannabis become
legal in California and Canada, Lexaria expects increased demand for its
superior-performing edible products. Its formulations further allow clients to
retain organic food claims as the DehydraTECHTM process does not use
Lexaria will work with new and improved formulations for a
variety of food products on a continuous basis throughout 2018 as it broadens
its ever growing universe of products under development for potential licensees.
This should shorten the technology licensing sales cycle and also assist
companies as they collaborate with Lexaria to develop and sell the
highest-performing products in their respective sales categories.
Lexaria Bioscience Corp. has developed
and out-licenses its disruptive delivery technology that promotes healthier
ingestion methods, lower overall dosing and higher effectiveness of lipophilic
active molecules. Lexaria has multiple patents pending in over 40 countries
around the world and has patents granted in the USA and in Australia for
utilization of its DehydraTECHTM delivery technology. Lexaria s
technology provides increases in intestinal absorption rates; more rapid
delivery to the bloodstream; and important taste-masking benefits, for orally
administered bioactive molecules including cannabinoids, vitamins, non-steroidal
anti-inflammatory drugs (NSAIDs), nicotine and other molecules.
For regular updates,
connect with Lexaria:
FOR FURTHER INFORMATION PLEASE CONTACT:
Alex Blanchard, Communications Manager
NetworkNewsWire (NNW)
FORWARD-LOOKING STATEMENTS
This release includes
forward-looking statements. Statements which are not historical facts are
forward-looking statements. The Company makes forward-looking public statements
concerning its expected future financial position, results of operations, cash
flows, financing plans, business strategy, products and services, competitive
positions, growth opportunities, plans and objectives of management for future