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Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Key Takeaway: Karyopharm Therapeutics has granted 1,850 restricted stock units to two new employees as part of its 2022 Inducement Stock Incentive Plan. These awards are intended to incentivize the new hires under Nasdaq Listing Rule 5635(c)(4). The RSUs will vest over three years, contingent on continued employment.
Price reaction · baseline $1.85 (2026-09-01 close) · hit after-hours · clean, no other KPTI news in the window
day 0 close · peak
-3.2%

Market Sentiment Analysis

POSITIVE FACTORS

  • Karyopharm is expanding its team with new hires.
  • The RSU grants are part of a strategic incentive plan.
  • The company is advancing innovative cancer therapies.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+14%
120-day peak, hindsight
Typical move
8.1%
average across 7 past catalysts
Cash runway
~6 mo
Medium dilution risk
Lead asset
KPT-8602
Phase 1 · Relapsed/Refractory Multiple Myeloma (RRMM)

Full Press Release Details

NEWTON, Mass., Sept. 1, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 1,850 restricted stock units (RSUs) to two newly-hired employees. These RSU awards were granted as of August 31, 2026 (the "Grant Date") pursuant to the Company's 2022 Inducement Stock Incentive Plan, as amended, as inducements material to the new employees entering into employment with Karyopharm in accordance with Nasdaq Listing Rule 5635(c)(4).
Each RSU award will vest over three years, with 33 1/3% of the shares underlying the RSU award vesting on each of the three consecutive anniversaries of the Grant Date. The vesting of each RSU award is subject to the employee's continued service as an employee of, or other service provider to, Karyopharm through the applicable vesting dates.

About Karyopharm Therapeutics

Karyopharm Therapeutics is a commercial-stage pharmaceutical company pioneering the science of nuclear export inhibition to develop differentiated therapies for patients with cancer. The Company's lead therapy, XPOVIO® (selinexor), is a first-in-class inhibitor of exportin 1 (XPO1). XPOVIO is marketed by the Company in the U.S. for adults with relapsed or refractory multiple myeloma and is approved as XPOVIO or NEXPOVIO® in more than 50 ex-U.S. countries and territories. Building on its leadership in XPO1 biology, Karyopharm is advancing selinexor's potential in hematological cancers, including in myelofibrosis. The Company is also exploring opportunities to evaluate XPO1 inhibition across myeloproliferative neoplasms using next-generation compounds, including eltanexor. Headquartered in Newton, Massachusetts, Karyopharm has an established, efficient, and scalable commercial infrastructure to bring novel therapeutic options to patients with cancer. For more information, visit www.karyopharm.com and follow Karyopharm on LinkedIn and on X at @Karyopharm.
XPOVIO ® and NEXPOVIO ® are registered trademarks of Karyopharm Therapeutics Inc.

Frequently Asked Questions

What are the RSUs granted by Karyopharm?

Karyopharm granted 1,850 restricted stock units to two new employees.

What is the vesting schedule for the RSUs?

The RSUs will vest over three years, with one-third vesting each year.

Under which rule were the RSUs granted?

The RSUs were granted under Nasdaq Listing Rule 5635(c)(4).

What is Karyopharm's lead therapy?

Karyopharm's lead therapy is XPOVIO® (selinexor), a cancer treatment.

Last updated: Sep 1, 2026