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Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

Key Takeaway: Karyopharm Therapeutics has granted 333 restricted stock units (RSUs) to a newly-hired employee as part of its 2022 Inducement Stock Incentive Plan. This award, effective from September 30, 2026, will vest over three years, contingent upon the employee's continued service. The move aligns with Nasdaq Listing Rule 5635(c)(4) and highlights Karyopharm's efforts to attract talent in the competitive biopharma sector.

Market Sentiment Analysis

POSITIVE FACTORS

  • Karyopharm is expanding its workforce with new hires.
  • The RSU award reflects the company's commitment to attracting talent.
  • Karyopharm is advancing innovative cancer therapies.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+14%
120-day peak, hindsight
Typical move
8.1%
average across 7 past catalysts
Cash runway
~6 mo
Medium dilution risk
Lead asset
KPT-8602
Phase 1 · Relapsed/Refractory Multiple Myeloma (RRMM)

Full Press Release Details

NEWTON, Mass., Oct. 1, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted 333 restricted stock units (RSUs) to one newly-hired employee. This RSU award was granted as of September 30, 2026 (the "Grant Date") pursuant to the Company's 2022 Inducement Stock Incentive Plan, as amended, as an inducement material to the new employee entering into employment with Karyopharm in accordance with Nasdaq Listing Rule 5635(c)(4).
The RSU award will vest over three years, with 33 1/3% of the shares underlying the RSU award vesting on each of the three consecutive anniversaries of the Grant Date. The vesting of the RSU award is subject to the employee's continued service as an employee of, or other service provider to, Karyopharm through the applicable vesting dates.

About Karyopharm Therapeutics

Karyopharm Therapeutics is a commercial-stage pharmaceutical company pioneering the science of nuclear export inhibition to develop differentiated therapies for patients with cancer. The Company's lead therapy, XPOVIO® (selinexor), is a first-in-class inhibitor of exportin 1 (XPO1). XPOVIO is marketed by the Company in the U.S. for adults with relapsed or refractory multiple myeloma and is approved as XPOVIO or NEXPOVIO® in more than 50 ex-U.S. countries and territories. Building on its leadership in XPO1 biology, Karyopharm is advancing selinexor's potential in hematological cancers, including in myelofibrosis. The Company is also exploring opportunities to evaluate XPO1 inhibition across myeloproliferative neoplasms using next-generation compounds, including eltanexor. Headquartered in Newton, Massachusetts, Karyopharm has an established, efficient, and scalable commercial infrastructure to bring novel therapeutic options to patients with cancer. For more information, visit www.karyopharm.com and follow Karyopharm on LinkedIn and on X at @Karyopharm.
XPOVIO ® and NEXPOVIO ® are registered trademarks of Karyopharm Therapeutics Inc.

Frequently Asked Questions

What is the purpose of the RSU grant by Karyopharm?

The RSU grant is an inducement for a newly-hired employee as per Nasdaq Listing Rule 5635.

How many RSUs were granted to the new employee?

Karyopharm granted 333 restricted stock units (RSUs) to the new employee.

What is the vesting schedule for the RSUs?

The RSUs will vest over three years, with one-third vesting each year.

What is Karyopharm's lead therapy?

Karyopharm's lead therapy is XPOVIO® (selinexor), a treatment for multiple myeloma.

Last updated: Oct 1, 2026