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DIRECTOR RESIGNATION Jaguar Health, Inc. (the "Company") Effective as of

Key Takeaway: DIRECTOR RESIGNATION Jaguar Health, Inc. (the "Company") Effective as of February 21, 2020 As the Company is aware, the holders of Series A Preferred Stock have ceased to beneficially own at least five percent of the outstanding voting securities of the Company, on an as-con

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DIRECTOR RESIGNATION
Jaguar Health, Inc. (the "Company")
Effective as of February 21, 2020
As the Company is aware, the holders of
Series A Preferred Stock have ceased to beneficially own at least five percent of the outstanding voting securities of the Company,
on an as-converted basis.
Accordingly, the undersigned, as a Series
A Director (as such term is defined in the Certificate of Designation of the Series A Preferred Stock) does hereby resign from
his position as a member of the board of directors (and all committees and subcommittees thereof) of the Company and any of its
subsidiaries, if applicable.
IN WITNESS WHEREOF, this Director Resignation
has been executed and delivered by the undersigned, effective as of date set forth above, without need for acceptance or further
action by the Company.1
/s/ Jeff Johnson
Jeff Johnson
Of course, as a technical matter, nothing contained in this Director Resignation shall be deemed to be a waiver of
any of the undersigned's rights or claims to any applicable insurance coverage of the Company and its subsidiaries, nor
to any advancement, indemnification and/or similar rights arising under, or in connection with, the undersigned's service
as a director of the Company (and/or any of its subsidiaries, if applicable).
Last updated: Feb 21, 2020