Century Therapeutics Appoints Accomplished Biotechnology Leaders Dr. Han Lee and Dr. Martin Murphy to Board of Directors PHILADELPHIA

Century Therapeutics Appoints Accomplished Biotechnology

Leaders Dr. Han Lee and Dr. Martin Murphy to Board of Directors

Dec. 9, 2025 -- Century Therapeutics, Inc. ( Century', NASDAQ: IPSC), a biotechnology company developing

induced pluripotent stem cell (iPSC)-derived cell therapies for autoimmune diseases and cancer, today announced the appointments of Han

Lee, Ph.D., M.B.A., and Martin Murphy, Ph.D., to its Board of Directors. As part of their appointments, Dr. Lee will serve as a member

of the Audit and the Compensation Committees and Dr. Murphy will serve as a member of the Compensation and the Nominating and Corporate

Governance Committees.

"We are pleased to welcome Dr. Lee and Dr. Murphy to

our Board at an important time for Century as we execute with discipline and focus to bring our most differentiated iPSC-derived cell

therapy programs, including CNTY-813 as a potentially curative, off-the-shelf investigational treatment for type 1 diabetes, closer to

patients living with high-impact diseases," said Brent Pfeiffenberger, Pharm.D., Chief Executive Officer of Century Therapeutics.

"With Dr. Lee's extensive capital formation and corporate development leadership experience and Dr. Murphy's

extensive experience in life science investment, company creation and strategic oversight of successfully evolving companies across the

public and private sectors, we look forward to benefitting from their combined expertise and contributions as we move with urgency to

bring our lead pipeline candidates into the clinic and deliver significant value for patients and stakeholders."

Dr. Han Lee most recently served as President and Chief Financial

Officer of ImmPACT Bio, Inc., a privately-owned clinical-stage biotechnology company, which was recently acquired by Lyell Immunopharma

in 2024. Prior to ImmPACT, he served in the position of Chief Financial Officer at Neogene Therapeutics, Inc. and, before that, at

Arcellx, Inc. Earlier in his career, Dr. Lee worked in corporate development and ventures at AstraZeneca plc. He holds a Ph.D.

in genetics and an M.B.A., both from Yale University, and a B.A. in molecular cell biology, with a genetics emphasis, and a minor in chemistry

from the University of California, Berkeley.

Dr. Martin Murphy currently holds various board chair and director

positions at several organizations, including Synairgen plc, Cora Biosciences Limited and Legal & General UK Universities Ventures

LP. Previously, he served as co-founder of Syncona Limited and Chief Executive Officer and investment committee chair of Syncona Investment

Management Limited. Prior to Syncona, Dr. Murphy served in roles of increasing responsibility at MVM Life Science Partners LLP, 3i

Group plc and McKinsey & Company. He holds a Ph.D. from the University of Cambridge and an M.A. in biochemistry from the University

About Century Therapeutics

Therapeutics (NASDAQ: IPSC) is a biotechnology company advancing a pipeline of induced pluripotent stem cell (iPSC)-derived cell therapies

with the potential to meaningfully address autoimmune diseases and cancer. The company's therapies are derived from its iPSC cell

foundry and leverage its novel immune evasion engineering technology, Allo-Evasion . Century believes its approach to developing

off-the-shelf cell therapies will expand patient access and provide advantages over existing cell therapies which will ultimately advance

the course of care. For more information on Century Therapeutics, please visit www.centurytx.com and connect with us on

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planned development, therapeutic potential and market opportunity. These statements involve known and unknown risks, uncertainties and

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advance our current and future product candidates through development activities, preclinical studies, and clinical trials; our ability

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to obtain clearance of our future IND or CTA submissions and commence and complete clinical trials on expected timelines, or at all; our

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the timing, scope and likelihood of regulatory filings and approvals, including final regulatory approval of our product candidates; the

impact of geopolitical issues, trade disputes and tariffs, banking instability and inflation on our business and operations, supply chain

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conducting our clinical trials as well as third-party suppliers and manufacturers; our ability to successfully commercialize our product

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members of management and our ability to maintain and successfully enforce adequate intellectual property protection. These and other

risks and uncertainties are described more fully in the "Risk Factors" section of our most recent filings with the Securities

and Exchange Commission and available at www.sec.gov. You should not rely on these forward-looking statements as predictions of future

events. The events and circumstances reflected in our forward-looking statements may not be achieved or occur, and actual results could

differ materially from those projected in the forward-looking statements. Moreover, we operate in a dynamic industry and economy. New

risk factors and uncertainties may emerge from time to time, and it is not possible for management to predict all risk factors and uncertainties

that we may face. Except as required by applicable law, we do not plan to publicly update or revise any forward-looking statements contained

herein, whether as a result of any new information, future events, changed circumstances or otherwise.

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Century Therapeutics

Senior Vice President, Finance