Ionis to present at upcoming investor conferences

CARLSBAD, Calif.--(BUSINESS WIRE)--Sep. 3, 2026--Ionis Pharmaceuticals, Inc.(Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences:

• 21stAnnualWells Fargo Healthcare ConferenceonThursday, September 10, 2026

• Morgan Stanley 24thAnnual Global Healthcare Conference onWednesday, September 16, 2026

A live webcast of these presentations can be accessed on the Investors & Media section of the Ionis website athttps://ir.ionis.com/events-and-presentations/upcoming-events. Replays will be available on the Ionis website within 48 hours and will be archived for a limited time.

For three decades, Ionis has invented medicines that bring better futures to people with serious diseases. Ionis currently has marketed medicines and a leading pipeline in neurology, cardiometabolic disease and select areas of high patient need. As the pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies in addition to advancing new approaches in gene editing. A deep understanding of disease biology and industry-leading technology propels our work, coupled with a passion and urgency to deliver life-changing advances for patients. To learn more about Ionis, visitIonis.comand follow us onX(Twitter),LinkedInandInstagram.

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Source: Ionis Pharmaceuticals, Inc.