Full Press Release Details
INmune Bio Inc. to Introduce NeuLiv
Program for Treatment of NASH
at H.C. Wainwright 21st Annual
Global Investment Conference
NeuLiv is the Third Drug Development
Program From Company's DN-TNF Platform
Presentation is Scheduled for 2.10
LA JOLLA, Calif., Sept. 4, 2019 (GLOBE
NEWSWIRE) -- INmune Bio, Inc. (NASDAQ: INMB), an immunotherapy company developing treatments that harness the patient's innate
immune system to fight disease, will introduce its NeuLiv development program for the treatment of nonalcoholic steatohepatitis
(NASH) as part of a presentation at the H.C. Wainwright 21st Annual Global Investment Conference.
Presentation Details:
Location: The Lotte New York Palace Hotel,
Date: Monday, September 9, 2019 at 2:10 p.m.
Presentation Room: Louis, 4th Floor
The presentation will be webcast live
on September 9 and will remain available for 90 days through the Investor Relations section of INmune Bio's website.
"NASH presents a significant unmet
medical need. We believe NeuLiv may enable us to target the underlying cause of NASH, to help stop the disease and allow
the liver to heal," said RJ Tesi, M.D., Chief Executive Officer of INmune Bio. "NeuLiv precisely targets soluble TNF,
a key cytokine driving pathologic chronic inflammation. Unlike treatments focused on addressing fibrosis directly, we believe NeuLiv
targets peripheral, regional and local causes of innate immune dysfunction that lead to chronic inflammation in patients with NASH.
We hope this strategy will prevent progression of the disease and allow hepatic repair mechanisms to function."
Innate immune dysregulation, also called
chronic inflammation, is a low-grade inflammatory state that, over time, has detrimental effects on organs, including the liver
and brain. NeuLiv , which is the third drug development program originating from INmune Bio's DN-TNF platform, is a
next generation TNF inhibitor that neutralizes soluble TNF (sTNF) without affecting trans-membrane TNF (tmTNF) or TNF receptors.
By targeting soluble TNF, NeuLiv may alter the complex immunobiology that causes the development and progression of NASH.
NASH is a progressive disease caused
by excessive fat accumulation in the liver that induces chronic inflammation, resulting in fibrosis that can lead to cirrhosis,
liver failure, cancer and death. By 2020, NASH is projected to become the leading cause of liver transplants in the U.S. No medications
are currently approved for the treatment of the disease.
About INmune Bio's DN-TNF Clinical Development Programs
INmune Bio has active development programs in Alzheimer's
disease and oncology originating from the DN-TNF platform. XPro1595 is set to begin this quarter a Phase I clinical trial in patients
with mild-to-moderate Alzheimer's disease who have biomarkers of neuroinflammation to determine if neutralizing soluble
TNF can decrease those biomarkers. In addition, INB03 just completed a Phase I open label, dose escalation trial in patients with
advanced cancer and will move to Phase II studies in the first half of next year.
INmune Bio, Inc. is a publicly traded (NASDAQ:
INMB) clinical-stage biotechnology company developing therapies targeting the innate immune system to fight disease. INmune Bio
is developing two product platforms, DN-TNF and INKmune, that reengineer the patient's innate immune system's response
to cancer and chronic inflammation. INKmune is a natural killer (NK) cell therapeutic that primes the patient's NK cells
to attack minimal residual disease. INB03 will be used as part of combination immunotherapy to prevent resistance to cancer immunotherapy.
XPro1595 targets microglial cell activation that causes neuroinflammation, which causes synaptic dysfunction and neuronal cell
death - a cause of Alzheimer's disease. INmune Bio's product platforms utilize a precision medicine approach
for the treatment of a wide variety of malignant and non-malignant diseases where innate immune dysfunction and chronic inflammation
play an important part of the core pathophysiology. To learn more, please visit www.inmunebio.com.
Safe Harbor Statement
Any statements contained in this press release
that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities
Litigation Reform Act of 1995. Any forward-looking statements contained herein are based on current expectations but are subject
to a number of risks and uncertainties. Actual results and the timing of certain events and circumstances may differ materially
from those described by the forward-looking statements as a result of these risks and uncertainties. INBO3 is still in clinical
trials and has not been approved and there cannot be any assurance that it will be approved. The factors that could cause
actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating
to the Company's ability to produce more drug for clinical trials; the availability of substantial additional funding for
the Company to continue its operations and to conduct research and development, clinical studies and future product commercialization;
and, the Company's business, research, product development, regulatory approval, marketing and distribution plans and strategies.
These and other factors are identified and described in more detail in the Company's filings with the Securities and Exchange
Commission, including the Company's Annual Report on Form 10-K for the year ended December 31, 2018, the Company's
Quarterly Reports on Form 10-Q and the Company's Current Reports on Form 8-K. The Company assumes no obligation to update
any forward-looking statements in order to reflect any event or circumstance that may arise after the date of this release.
KCSA Strategic Communications
Valter Pinto / Daniela Guerrero
PH: (212) 896-1254 / (347)