Full Press Release Details
| NASDAQ: INM |
| Suite 310-815 W. Hastings St. |
| Vancouver, BC, Canada V6C 1B4 |
| Tel: +1.604.669.7207 |
| Email: info@inmedpharma.com |
| www.inmedpharma.com |
InMed Pharmaceuticals Provides Business
Update and Milestones for 2024
Vancouver, BC - January 16, 2024
- InMed Pharmaceuticals Inc. ("InMed" or the "Company") (Nasdaq: INM), a leader in the manufacturing,
development and commercialization of rare cannabinoids and proprietary cannabinoid analogs, today outlines key accomplishments from 2023
and provides key strategic priorities for 2024.
Eric A. Adams, InMed President and CEO,
commented, "In 2023, we experienced significant progress in both InMed's pharmaceutical drug development and in BayMedica's
health and wellness initiatives. Our primary accomplishments throughout the year included a number of key milestones, such as the completion
of a Phase 2 clinical trial and the launch of two new preclinical programs targeting the treatment of Alzheimer's disease and Age-related
Macular Degeneration ("AMD")."
Adams continued, "As we embark
on 2024, we are placing increased emphasis on proprietary small molecule drug development candidates in our pharmaceutical pipeline with
two exciting new programs addressing critical unmet medical needs. Firstly, INM-901 for the treatment of Alzheimer's disease is
showing promise via multiple mechanisms of action, including an increase in neuroprotection and an improvement in neuronal function via
neuritogenesis. Secondly, INM-089 for the treatment of AMD appears to play a role in the preservation of retinal function, proactively
protecting the retinal cells that are responsible for vision. Our focus on developing proprietary cannabinoid analogs over the past two
years has started to pay dividends, evident in their utilization in these two new preclinical programs."
"Concurrently, BayMedica continues
to drive robust year-over-year revenue growth. The foreseeable future looks promising for the health and wellness segment as demand for
minor cannabinoid ingredients continues to gain momentum."
Key accomplishments in 2023
INM-901 in the treatment of Alzheimer's
The Company is highly encouraged by
the initial preclinical data from in vitro and in vivo studies. Existing external research indicates that various cannabinoids
have been shown to have a wide range of impact on Alzheimer's pathology. Newly approved Alzheimer's disease medications primarily
address symptoms related to memory and cognitive function via the reduction of beta-amyloid plaques. Some approved treatments may slow
the rate of cognitive decline, but no treatment has been shown to reverse disease effects. INM-901 appears to be active via multiple mechanisms
of action; early research indicates INM-901 has the potential to be effective in reducing beta-amyloid plaques and has the potential to
provide neuroprotective effects and enhanced neuronal function. Additionally, INM-901 treated groups demonstrated improved behavioral,
cognitive and memory outcomes in several Alzheimer's proof-of-concept studies using in vivo disease models.
The Company has initiated long-term
(6-month) preclinical studies in behavioral models to further evaluate the potential impact of INM-901 in Alzheimer's disease. Preparations
are underway for the subsequent phase of advanced preclinical studies, encompassing drug distribution, metabolism and active pharmaceutical
ingredient ("API") and drug product formulation/ manufacturing.
INM-089 in the treatment of AMD
Based on the previous research conducted
with InMed's initial ocular drug candidate, INM-088 in the treatment of glaucoma, the Company leveraged its know-how to advance
preclinical work with the use of a proprietary analog for the treatment of AMD. Our preclinical research has shown promising results in
preserving retinal function, proactively protecting retinal cells, and enhancing the thickness of the outer nuclear layer of the retina
where photoreceptors are situated.
The Company is currently engaged in
API and drug product formulation work and expects to initiate Investigational New Drug ("IND")-enabling studies in mid-2024,
with the anticipation of filing an IND application with regulatory authorities in calendar 1H 2025.
INM-755 - In the treatment
The comprehensive data and
findings from the Phase 2 clinical trial will soon be available on the National Institutes of Health ("NIH")
clinicaltrials.gov website and the European Union Clinical Trials Register website. Additionally, an abstract will soon be published
in Itch, the official journal of the International Forum for the Study of Itch.
The Company believes that INM-755 holds
promise for further advancement in the treatment of chronic itch and other related ailments and the Company is currently seeking partnerships
for continued development. Due to several factors, including the small size of the trial and the clinically important anti-itch activity
of the underlying cream without study drug, results were not statistically significant, but we believe the results are clinically important
based on additional analyses.
BayMedica - Ingredients supplier to the
health and wellness industry
BayMedica continues to be a leading low-cost/high
quality manufacturer of certain non-psychoactive rare cannabinoids and is an ingredients supplier to brands within the health and wellness
industry. BayMedica demonstrated significant year-over-year revenue growth throughout 2023 and remains focused on making strategic decisions
to capitalize on the revenue generation opportunities as the rare cannabinoid market continues to mature. BayMedica has embraced a predominantly
distributor model to strategically expanding coverage across the US and thereby further amplifying BayMedica's reach into different
market segments. In 2024, we anticipate consumer brands will increasingly embrace rare cannabinoid ingredients, integrating them into
new product formulations and formats.
InMed: InMed Pharmaceuticals is a global leader in the manufacturing, development and commercialization of rare cannabinoids and proprietary
cannabinoid analogs. Together with our subsidiary, BayMedica, we have unparalleled cannabinoid manufacturing capabilities to serve a spectrum
of consumer markets, including pharmaceutical and health and wellness. We are a clinical-stage company developing a pipeline of rare cannabinoid
therapeutics and dedicated to delivering new treatment alternatives to patients that may benefit from cannabinoid-based pharmaceutical
drugs. For more information, visit www.inmedpharma.com.
Vice President, Investor Relations
and Corporate Communications
Cautionary Note Regarding Forward-Looking Information:
This news release contains "forward-looking
information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning
of applicable securities laws. Forward-looking statements are frequently, but not always, identified by words such as "expects",
"anticipates", "believes", "intends", "potential", "possible", "would"
and similar expressions. Such statements, based as they are on current expectations of management, inherently involve numerous risks,
uncertainties and assumptions, known and unknown, many of which are beyond our control. Forward-looking information is based on management's
current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially
from those described in the forward-looking statements. Forward-looking information in this news release includes statements about: placing
increased emphasis on proprietary small molecule drug development candidates; INM-901 shows promise via multiple mechanisms of action,
including an increase in neuroprotection and an improvement in neuronal function via neuritogenesis and has potential to be effective
in reducing beta-amyloid plaques; INM-089 appears to play a role in the preservation of retinal function, proactively protecting the retinal
cells that are responsible for vision and enhancing the thickness of the outer nuclear layer of the retina; the foreseeable future looks
promising for the health and wellness segment as demand for minor cannabinoids ingredients continues to gain momentum; the Company is
highly encouraged by the initial preclinical data from in vitro and in vivo studies; preparations are underway for the subsequent
phase of advanced preclinical studies, encompassing drug distribution, metabolism and API and drug product formulation and manufacturing;
expecting to initiate IND-enabling GLP studies in mid-2024, with the anticipation of filing an IND in calendar 1H 2025; BayMedica making
strategic decisions to capitalize on the revenue generation opportunities; anticipating brands increasingly embracing rare cannabinoid
ingredients, integrating them into new product formulations and statements relating to the Company's 2024 strategic priorities generally.
With respect to the forward-looking information
contained in this news release, InMed has made numerous assumptions regarding, among other things: continued economic, regulatory and
market stability; delivering new therapeutic alternatives to patients that may benefit from cannabinoid-based
pharmaceutical drugs; and developing a pipeline of cannabinoid-based pharmaceutical drug candidates. While InMed considers these
assumptions to be reasonable, these assumptions are inherently subject to significant business, economic, competitive, market and social
uncertainties and contingencies.
Additionally, there are known and unknown risk
factors which could cause InMed's actual results, performance or achievements to be materially different from any future results, performance
or achievements expressed or implied by the forward-looking information contained herein. Known risk factors include, among others: regulatory