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Immix Biopharma’s NXC-201 NEXICART-2 Interim Clinical Trial Results Selected for Oral Presentation at ASH 2026

Key Takeaway: Immix Biopharma will present interim results of its NXC-201 clinical trial at the ASH 2026 meeting. This therapy targets relapsed/refractory AL Amyloidosis, a severe condition affecting organ function. The company has received multiple designations from the FDA, indicating its potential significance in treatment.

Market Sentiment Analysis

POSITIVE FACTORS

  • NXC-201 shows promise in treating AL Amyloidosis.
  • Presentation at ASH 2026 highlights significant research.
  • Breakthrough Therapy Designation awarded by the FDA.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+46%
120-day peak, hindsight
Typical move
9.6%
average across 3 past catalysts
Cash runway
~56 mo
Low dilution risk
Lead asset
NXC-201
Phase 3 · Light Chain (AL) Amyloidosis

Full Press Release Details

– Data will be presented on Monday, December 14, 2026 at 11:15 AM CDT –
LOS ANGELES, CA, Nov. 04, 2026 (GLOBE NEWSWIRE) -- Immix Biopharma, Inc. (“Immix”, “Company”, “We” or “Us” or ”IMMX”), a global leader in AL Amyloidosis, today announced that it will present an NXC-201 abstract at the upcoming American Society of Hematology (ASH) 68th Annual Meeting and Exposition to be held December 12-15, 2026, in New Orleans, LA.

ASH Oral Presentation Details:

Event 68th ASH Annual Meeting and Exposition, New Orleans, LA
Title “45-patient safety and efficacy data for NXC-201 from Nexicart-2, the first U.S. trial of CAR-T in relapsed/refractory AL amyloidosis”
Presentation Date/Time (Central Time) Publication #826 Session Date: Monday, December 14, 2026 Session Name: 652. MGUS, Amyloidosis, and Other Non-Myeloma Plasma Cell Dyscrasias: Clinical and Epidemiological: Advancing Treatment Strategies in AL Amyloidosis Session Time: 10:30 AM -12:00 PM Presentation Time: 11:15 AM
About AL Amyloidosis Amyloid light-chain (AL) amyloidosis is a devastating disease where the immune system, that’s supposed to protect, instead continuously produces toxic light chains that build up in organs including the heart, kidney, and liver, causing organ failure and death.
AL amyloidosis is the most common form of amyloidosis according to the National Institutes of Health. The number of patients in the U.S. with relapsed/refractory AL Amyloidosis is estimated to be growing at 12% per year according to Staron, et al Blood Cancer Journal, to approximately 30,506 patients in 2026.
The Amyloidosis market was $6.2 billion in 2025, and is expected to reach $6.6 billion in 2026, according to Grand View Research.
About Immix Biopharma, Inc. Immix Biopharma, Inc. (Immix) (Nasdaq: IMMX) is a global leader in AL Amyloidosis. AL Amyloidosis is a devastating disease where the immune system, that’s supposed to protect, instead continuously produces toxic light chains that build up in organs including the heart, kidney, and liver, causing organ failure and death. Our lead candidate is sterically-optimized BCMA-targeted chimeric antigen receptor T (CAR-T) cell therapy NXC-201 with a proprietary CD3ζ, CD8 hinge and binder “digital filter” designed to filter out non-specific activation. NXC-201 teaches the immune system to recognize and eliminate the source of the toxic light chains. NXC-201 is being evaluated in the U.S. multi-center study for relapsed/refractory AL Amyloidosis NEXICART-2 (NCT06097832), with a potentially registrational design. NXC-201 has been awarded Breakthrough Therapy Designation (BTD) and Regenerative Medicine Advanced Therapy (RMAT) by the US FDA and Orphan Drug Designation (ODD) by FDA and in the EU by the EMA.

Contacts Mike Moyer LifeSci Advisors mmoyer@lifesciadvisors.com

Company Contact irteam@immixbio.com

Frequently Asked Questions

What is NXC-201?

NXC-201 is a CAR-T cell therapy targeting AL Amyloidosis.

When will the results be presented?

The results will be presented on December 14, 2026.

What designations has NXC-201 received?

NXC-201 has received Breakthrough Therapy and RMAT designations.

What is AL Amyloidosis?

AL Amyloidosis is a disease where toxic light chains damage organs.

Last updated: Nov 4, 2026