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Immunocore Holdings plc
Unaudited Condensed Consolidated Interim Financial Statements
Unaudited Condensed Consolidated Statements of Profit / (Loss) and Comprehensive (Loss) / Income
| Three Months Ended September 30, | Nine Months Ended September 30, | |||||||||||||||||||
| Notes | 2023 '000 | 2022 '000 | 2023 '000 | 2022 '000 | ||||||||||||||||
| Product revenue, net | 3 | 49,719 | 33,252 | 137,285 | 64,926 | |||||||||||||||
| Pre-product revenue, net | 3 | - | 3,051 | - | 9,588 | |||||||||||||||
| Total revenue from sale of therapies | 49,719 | 36,303 | 137,285 | 74,514 | ||||||||||||||||
| Collaboration revenue | 3 | 1,769 | 4,896 | 6,508 | 21,161 | |||||||||||||||
| Total revenue | 51,488 | 41,199 | 143,793 | 95,675 | ||||||||||||||||
| Cost of product revenue | (220 | ) | (63 | ) | (1,284 | ) | (345 | ) | ||||||||||||
| Research and development expenses | (31,679 | ) | (23,301 | ) | (88,895 | ) | (62,032 | ) | ||||||||||||
| Selling and administrative expenses | 4 | (20,288 | ) | (11,663 | ) | (87,473 | ) | (50,579 | ) | |||||||||||
| Operating (loss) / profit | (699 | ) | 6,172 | (33,859 | ) | (17,281 | ) | |||||||||||||
| Finance income | 5 | 4,091 | 597 | 10,049 | 725 | |||||||||||||||
| Finance costs | (1,632 | ) | (1,785 | ) | (4,817 | ) | (4,515 | ) | ||||||||||||
| Net finance income / (costs) | 2,459 | (1,188 | ) | 5,232 | (3,790 | ) | ||||||||||||||
| Profit / (loss) before taxation | 1,760 | 4,984 | (28,627 | ) | (21,071 | ) | ||||||||||||||
| Income tax credit / (charge) | 6 | 144 | 1,244 | (243 | ) | 5,050 | ||||||||||||||
| Profit / (loss) for the period | 1,904 | 6,228 | (28,870 | ) | (16,021 | ) | ||||||||||||||
| Other comprehensive loss | ||||||||||||||||||||
| Other comprehensive loss that is or may be reclassified to profit or loss in subsequent periods: | ||||||||||||||||||||
| Exchange differences on translation of foreign operations | (2,603 | ) | (1,730 | ) | (1,169 | ) | (1,848 | ) | ||||||||||||
| Total other comprehensive loss for the period | (2,603 | ) | (1,730 | ) | (1,169 | ) | (1,848 | ) | ||||||||||||
| Total comprehensive (loss) / income for the period | (699 | ) | 4,498 | (30,039 | ) | (17,869 | ) | |||||||||||||
| Basic earnings / (loss) per share - | 7 | 0.04 | 0.13 | (0.59 | ) | (0.36 | ) | |||||||||||||
| Diluted earnings / (loss) per share - | 7 | 0.04 | 0.12 | (0.59 | ) | (0.36 | ) |
The accompanying notes form part of these unaudited condensed consolidated interim financial statements.
Immunocore Holdings plc
Unaudited Condensed Consolidated Interim Financial Statements
Unaudited Condensed Consolidated Statements of Financial Position as at
| Notes | September 30, 2023 '000 | December 31, 2022 '000 | ||||||||||
| Non-current assets | ||||||||||||
| Property, plant and equipment | 8 | 8,025 | 6,472 | |||||||||
| Intangible assets | 1,589 | 410 | ||||||||||
| Right of use assets | 25,832 | 25,173 | ||||||||||
| Other non-current assets | 8,846 | 7,342 | ||||||||||
| Deferred tax asset | 6 | 4,135 | 4,240 | |||||||||
| Total non-current assets | 48,427 | 43,637 | ||||||||||
| Current assets | ||||||||||||
| Inventory | 1,857 | 943 | ||||||||||
| Trade and other receivables | 9 | 49,880 | 46,711 | |||||||||
| Tax receivable | 6 | - | 11,688 | |||||||||
| Cash and cash equivalents | 363,955 | 332,539 | ||||||||||
| Total current assets | 415,692 | 391,881 | ||||||||||
| Total assets | 464,119 | 435,518 | ||||||||||
| Equity | ||||||||||||
| Share capital | 10 | 99 | 97 | |||||||||
| Share premium | 146,205 | 123,751 | ||||||||||
| Foreign currency translation reserve | (4,266 | ) | (3,097 | ) | ||||||||
| Other reserves | 337,847 | 337,847 | ||||||||||
| Share-based payment reserve | 11 | 101,781 | 81,411 | |||||||||
| Accumulated deficit | (290,123 | ) | (261,253 | ) | ||||||||
| Total equity | 291,543 | 278,756 | ||||||||||
| Non-current liabilities | ||||||||||||
| Non-current accruals | 2,531 | 1,479 | ||||||||||
| Interest-bearing loans and borrowings | 38,484 | 39,500 | ||||||||||
| Deferred revenue | 3 | 4,331 | 4,331 | |||||||||
| Lease liabilities | 29,469 | 28,248 | ||||||||||
| Provisions | 153 | 114 | ||||||||||
| Total non-current liabilities | 74,968 | 73,672 | ||||||||||
| Current liabilities | ||||||||||||
| Trade and other payables | 12 | 93,135 | 75,076 | |||||||||
| Corporation tax liability | 6 | 367 | - | |||||||||
| Interest-bearing loans and borrowings | 1,024 | - | ||||||||||
| Deferred revenue | 3 | 1,602 | 6,408 | |||||||||
| Lease liabilities | 1,445 | 1,555 | ||||||||||
| Provisions | 35 | 51 | ||||||||||
| Total current liabilities | 97,608 | 83,090 | ||||||||||
| Total liabilities | 172,576 | 156,762 | ||||||||||
| Total equity and liabilities | 464,119 | 435,518 |
The accompanying notes form part of these unaudited condensed consolidated interim financial statements.
Immunocore Holdings plc
Unaudited Condensed Consolidated Interim Financial Statements
Unaudited Condensed Consolidated Statements of Changes in Equity
| Notes | Share capital '000 | Share premium '000 | Foreign currency translation reserve '000 | Share- based payment reserve '000 | Other reserve '000 | Accumulated deficit '000 | Total equity '000 | ||||||||||||||||||||||||
| At January 1, 2023 | 97 | 123,751 | (3,097 | ) | 81,411 | 337,847 | (261,253 | ) | 278,756 | ||||||||||||||||||||||
| Loss for the period | - | - | - | - | - | (28,870 | ) | (28,870 | ) | ||||||||||||||||||||||
| Other comprehensive loss | - | - | (1,169 | ) | - | - | - | (1,169 | ) | ||||||||||||||||||||||
| Total comprehensive loss for the period | - | - | (1,169 | ) | - | - | (28,870 | ) | (30,039 | ) | |||||||||||||||||||||
| Exercise of share options | 10, 11 | 2 | 22,454 | - | - | - | - | 22,456 | |||||||||||||||||||||||
| Equity-settled share-based payment transactions | 11 | - | - | - | 20,370 | - | - | 20,370 | |||||||||||||||||||||||
| At September 30, 2023 | 99 | 146,205 | (4,266 | ) | 101,781 | 337,847 | (290,123 | ) | 291,543 |
| Notes | Share capital '000 | Share premium '000 | Foreign currency translation reserve '000 | Share- based payment reserve '000 | Other reserve '000 | Accumulated deficit '000 | Total equity '000 | |||||||||||||||||||||||||
| At January 1, 2022 | 88 | 212,238 | 89 | 54,357 | 386,167 | (481,392 | ) | 171,547 | ||||||||||||||||||||||||
| Loss for the period | - | - | - | - | - | (16,021 | ) | (16,021 | ) | |||||||||||||||||||||||
| Other comprehensive loss | - | - | (1,848 | ) | - | - | - | (1,848 | ) | |||||||||||||||||||||||
| Total comprehensive loss for the period | - | - | (1,848 | ) | - | - | (16,021 | ) | (17,869 | ) | ||||||||||||||||||||||
| Exercise of share options | 1 | 4,535 | - | - | - | - | 4,536 | |||||||||||||||||||||||||
| Capital reduction in Group's parent company | - | (213,043 | ) | - | - | (48,320 | ) | 261,363 | - | |||||||||||||||||||||||
| Issue of share capital | 7 | 116,417 | - | - | - | - | 116,424 | |||||||||||||||||||||||||
| Equity-settled share-based payment transactions | 11 | - | - | - | 20,181 | - | - | 20,181 | ||||||||||||||||||||||||
| At September 30, 2022 | 96 | 120,147 | (1,759 | ) | 74,538 | 337,847 | (236,050 | ) | 294,819 |
The accompanying notes form part of these unaudited condensed consolidated interim financial statements.
Immunocore Holdings plc
Unaudited Condensed Consolidated Interim Financial Statements
Unaudited Condensed Consolidated Statements of Cash Flows
| Nine Months Ended September 30, | ||||||||||||
| Notes | 2023 '000 | 2022 '000 | ||||||||||
| Cash flows from operating activities | ||||||||||||
| Loss for the period | (28,870 | ) | (16,021 | ) | ||||||||
| Adjustments for: | ||||||||||||
| Equity settled share-based payment expense | 11 | 20,370 | 20,181 | |||||||||
| Depreciation | 3,969 | 4,794 | ||||||||||
| Net finance (income) / costs | (5,232 | ) | 3,790 | |||||||||
| Foreign exchange movements | (550 | ) | (20,498 | ) | ||||||||
| Other | 11 | (1 | ) | |||||||||
| Income tax charge / (credit) | 243 | (5,050 | ) | |||||||||
| Working capital adjustments: | ||||||||||||
| Increase in trade and other receivables and other non-current assets | (4,894 | ) | (25,021 | ) | ||||||||
| Increase in trade and other payables | 18,717 | 27,501 | ||||||||||
| Decrease in current and non-current deferred revenue | (4,806 | ) | (20,177 | ) | ||||||||
| Other working capital movements | 175 | (807 | ) | |||||||||
| Cash used in operations | (867 | ) | (31,309 | ) | ||||||||
| R&D tax credits received | 6 | 12,566 | - | |||||||||
| Taxation paid | 6 | (180 | ) | (614 | ) | |||||||
| Net cash from / (used in) operating activities | 11,519 | (31,923 | ) | |||||||||
| Cash flows from investing activities | ||||||||||||
| Proceeds from sale of property, plant and equipment | - | 5 | ||||||||||
| Purchase of property, plant and equipment | (3,776 | ) | (869 | ) | ||||||||
| Purchase of intangible assets | (1,178 | ) | - | |||||||||
| Interest income receipts | 9,407 | 725 | ||||||||||
| Net cash flows from / (used in) investing activities | 4,453 | (139 | ) | |||||||||
| Cash flows from financing activities | ||||||||||||
| Gross proceeds from issue of share capital | - | 116,812 | ||||||||||
| Costs from issue of share capital | - | (388 | ) | |||||||||
| Exercise of share options | 10, 11 | 22,456 | 4,536 | |||||||||
| Interest paid | (5,077 | ) | (3,050 | ) | ||||||||
| Repayment of lease liabilities | (1,117 | ) | (2,265 | ) | ||||||||
| Net cash flows from financing activities | 16,262 | 115,645 | ||||||||||
| Increase in cash and cash equivalents | 32,234 | 83,583 | ||||||||||
| Net foreign exchange difference on cash held | (818 | ) | 25,720 | |||||||||
| Cash and cash equivalents at beginning of the period | 332,539 | 237,886 | ||||||||||
| Cash and cash equivalents at end of the period | 363,955 | 347,189 |
The accompanying notes form part of these unaudited condensed consolidated interim financial statements.
Immunocore Holdings plc
Unaudited Condensed Consolidated Interim Financial Statements
Notes to the Financial Statements
1. Organization and nature of business
Immunocore Holdings plc (the "Company") is a public limited company incorporated in England and Wales and has the following wholly owned subsidiaries:
Immunocore Limited, Immunocore LLC, Immunocore Commercial LLC, Immunocore Ireland Limited, Immunocore GmbH, and Immunocore Nominees Limited (collectively referred to as the "Group").
The Company's American Depositary Shares ("ADSs") began trading on the Nasdaq Global Select Market under the ticker symbol "IMCR" on February 5, 2021,
following its initial public offering ("IPO"). The IPO and concurrent private placement generated net proceeds of 210,985,000 ($286,887,000) after underwriting discounts, commissions and directly attributable offering expenses. In July 2022, the
Company raised net proceeds of 116,424,000 ($139,515,000) through the sale of its ordinary shares in the form of ADSs and non-voting ordinary shares in a private placement.
The principal activity of the Group is pioneering the development and sale of a novel class of TCR bispecific immunotherapies called ImmTAX - Immune mobilizing monoclonal TCRs Against X disease - designed to treat a broad range of diseases, including cancer, infectious and autoimmune diseases. Leveraging its proprietary, flexible, off-the-shelf ImmTAX
platform, the Group is developing a deep pipeline in multiple therapeutic areas, including four clinical stage programs in oncology and infectious disease, advanced pre-clinical programs in autoimmune disease and multiple earlier pre-clinical
In 2022, the Group received approval for its lead product, KIMMTRAK, for the treatment of unresectable metastatic uveal melanoma from the U.S. Food and
Drug Administration the European Commission and other health authorities. KIMMTRAK is now approved in over 35 countries and the Group has commercially launched in the United States, Germany and France, among other territories, with further
commercial launches underway in additional territories where it has received approval.
2. Significant accounting policies
Basis of preparation and statement of compliance
The unaudited condensed consolidated interim financial statements ("interim financial statements") as at and for the three and nine months ended September 30, 2023 and 2022 have been prepared in
accordance with International Accounting Standard 34, "Interim Financial Reporting" ("IAS 34"). The accounting policies, including the Group's Critical accounting estimates, applied in these interim
financial statements are the same as those applied in the Group's consolidated financial statements as at and for the year ended December 31, 2022.
The unaudited condensed consolidated interim financial statements do not include all of the information required for the full annual financial statements and should be read in conjunction with
the annual consolidated financial statements of the Group for the year ended December 31, 2022 included in the Company's Annual Report on Form 20-F, filed with the Securities and Exchange Commission on March 1, 2023 (the "Annual Report").
The unaudited condensed consolidated interim financial statements have been prepared under the historical cost basis, as modified by the recognition of certain financial instruments measured at
fair value and are presented in pounds sterling which is the Company's functional currency. All values are rounded to the nearest thousand, except where otherwise indicated.
Date of authorization
These unaudited condensed consolidated interim financial statements were approved by the Board of Directors (the "Board") on November 7, 2023, and signed on its behalf by Dr. Bahija Jallal, Chief
Adoption of new accounting standards
There have been no new accounting standards adopted by the Group in the three and nine months ended September 30, 2023 which have had a material impact on these unaudited condensed consolidated
interim financial statements. There are no standards issued but not yet effective that the Group expects to have a material impact on its financial statements.
The Group reported cash and cash equivalents of 363,955,000 and net current assets of 318,084,000 at September 30, 2023, with an operating loss for the three and nine months ended
September 30, 2023 of 699,000 and 33,859,000 respectively, and net cash from operating activities for the nine months ended September 30, 2023 of 11,519,000. The positive operational cash inflow was largely
due to R&D tax credits received, and generated net product revenue of 49,719,000 and 137,285,000 for the three and nine months ended September 30, 2023, respectively.
In assessing the going concern assumptions, management has undertaken an assessment of the current business and strategy forecasts covering a twelve month
period, which includes anticipated KIMMTRAK revenue. In assessing the downside risks, the Board has also considered scenarios incorporating a range of revenue arising from KIMMTRAK sales. As part of considering the downside risks, the Board has
considered the impact of the current macroeconomic environment, such as the effects of pandemics or epidemics and other potential economic impacts including the war in Ukraine and the conflict between Hamas and Israel, and related geopolitical
tensions, as well as global inflation, liquidity concerns at banks and financial institutions, capital market instability, interest and exchange rate fluctuations, and increases in commodity, energy and fuel prices as well as supply chain
disruptions. The Board has concluded that while these may have a future impact on the Group's business and implementation of its strategy and plans, it anticipates that any such impact will be minimal on clinical trials or other business activities
over the period assessed for going concern purposes. As of the date of these financial statements, the Group is not aware of any specific event or circumstance that would require the Group to update its estimates, assumptions and judgments or
revise the carrying value of its assets or liabilities. Actual results could differ from these estimates, and any such differences may be material to the Group's financial statements.
Given the current cash position and the assessment performed, the Board believes that the Group will have sufficient funds to continue to meet its liabilities as they fall due for a
period of at least twelve months from the date of issue of these unaudited condensed consolidated interim financial statements and therefore, the Group has prepared the financial statements on a going concern basis. This scenario is based
on the Group's lower range of anticipated revenue levels. As the Group continues to incur significant expenses in the pursuit of its business strategy, including further commercialization and marketing plans for
KIMMTRAK, additional funding will be needed before further existing clinical and preclinical programs may be expected to reach commercialization, which would potentially lead to additional operational cash inflows. Until the Group can generate
revenue from product sales sufficient to fund its ongoing operations and further develop its pipeline, if ever, it expects to finance its operations through a combination of public or private equity offerings and debt financings or other sources,
such as potential collaboration agreements, strategic alliances and licensing arrangements.
Estimates and judgments
The preparation of the unaudited condensed consolidated interim financial statements in conformity with IAS 34 requires management to make judgments, estimates and assumptions.
These judgments, estimates and assumptions affect the reported assets and liabilities as well as contingent liabilities and income and expenses in the financial period. The estimates and associated assumptions are based on information available
when the unaudited condensed consolidated interim financial statements are prepared, historical experience and various other factors which are believed to be reasonable under the circumstances the results of which form the basis of making
judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Existing circumstances and assumptions about future developments, however, may change due to market
changes or circumstances arising that are beyond the Group's control. Hence, estimates may vary from the actual values. The estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognized in
the period in which the estimate is revised if the revision affects only that period or the period of revision and future periods if this revision affects both current and future periods.
Judgments and estimates made, including Critical accounting estimates, together with the Group's significant accounting policies, are disclosed in the consolidated financial statements of the
Group for the year ended December 31, 2022, and are presented in the Group's Annual Report. There have been no significant updates to the Group's estimates and accounting policies for the three and nine months ended September 30, 2023.
The Group operates in one operating segment. The Group's chief operating decision maker, its Chief Executive Officer, manages the Group's operations on an integrated basis for the purposes of allocating resources.
Revenue is presented by type, and net of deductions in the table below.
| For the Three Months Ended September 30, | For the Nine Months Ended September 30, | |||||||||||||||
| 2023 '000 | 2022 '000 | 2023 '000 | 2022 '000 | |||||||||||||
| Product revenue, net | 49,719 | 33,252 | 137,285 | 64,926 | ||||||||||||
| Pre-product revenue, net | - | 3,051 | - | 9,588 | ||||||||||||
| Total revenue from sale of therapies | 49,719 | 36,303 | 137,285 | 74,514 | ||||||||||||
| Collaboration revenue | ||||||||||||||||
| Eli Lilly | - | - | - | 7,361 | ||||||||||||
| Genentech | 1,769 | 4,896 | 6,508 | 13,800 | ||||||||||||
| Total collaboration revenue | 1,769 | 4,896 | 6,508 | 21,161 | ||||||||||||
| Total revenue | 51,488 | 41,199 | 143,793 | 95,675 |
Eli Lilly and Genentech are based in the United States. Net product revenue from the sale of KIMMTRAK, and net pre-product revenue from the sale of tebentafusp as part of a compassionate use and early access program
are presented by region based on the location of the customer below.
| For the Three Months Ended September 30, | For the Nine Months Ended September 30, | |||||||||||||||
| 2023 '000 | 2022 '000 | 2023 '000 | 2022 '000 | |||||||||||||
| United States | 34,500 | 22,508 | 96,845 | 48,327 | ||||||||||||
| Europe | 15,012 | 13,034 | 39,529 | 25,423 | ||||||||||||
| Rest of World | 207 | 761 | 911 | 764 | ||||||||||||
| Total revenue from sale of therapies | 49,719 | 36,303 | 137,285 | 74,514 |
Product revenue, net
During the three and nine months ended September 30, 2023, the Group recognized 49,719,000 and 137,285,000 of net product revenue, respectively, relating to the sale of KIMMTRAK primarily in
the United States and Europe following marketing approvals in 2022 and subsequent commercial launches. Revenue is presented after estimated deductions for rebates, chargebacks, other customer fees and returns.
Pre-product revenue, net
There was no pre-product revenue during the three and nine months ended September 30, 2023, following the transition to the commercial sale of KIMMTRAK in
France in the second half of 2022. In the three and nine months ended September 30, 2022, the Group recognized 3,051,000 and 9,588,000 of net pre-product revenue, respectively, relating to the sale of tebentafusp under a compassionate use and
early access program in France after estimated deductions for rebates and returns.
Genentech Collaboration
During the three and nine months ended September 30, 2023, the Group recognized 1,769,000 and 6,508,000 of revenue, respectively, relating to the 2018 Genentech agreement and IMC-C103C (for the
three and nine months ended September 30, 2022: 4,896,000 and 13,800,000).
In February 2023, Genentech accepted our proposal to cease co-funding the development of MAGE-A4 HLA-A02 targeted programs, except for our equal share of the wind-down costs of the IMC-C103C
Phase 1 clinical trial.
Eli Lilly Collaboration
During the three and nine months ended September 30, 2023, the Group recognized no revenue relating to the Eli Lilly Collaboration (for the three and nine months ended September 30, 2022: nil and 7,361,000,
The Group released the remaining deferred revenue attributed to the third target under the Eli Lilly Collaboration after the parties agreed to terminate the agreement with Eli
Lilly during the three months ended March 31, 2022.
Of the total revenue recognized during the three and nine months ended September 30, 2023, 1,602,000 and 4,806,000, respectively, was included in deferred revenue at January 1, 2023. No collaboration revenue was
recognized in the three and nine months ended September 30, 2023 relating to performance obligations satisfied in previous years (for the three and nine months ended September 30, 2022: nil). The remaining current
deferred revenue as at September 30, 2023 relates to the Genentech agreement. The Group expects to recognize this remaining revenue within the next year.
Non-current deferred revenue in the unaudited condensed consolidated interim statement of financial position as at September 30, 2023 and December 31, 2022, respectively, relates to the Group's non-refundable payment