Full Press Release Details
BOSTON, March 07, 2022 (GLOBE NEWSWIRE) -- Ikena Oncology, Inc. (Nasdaq: IKNA), a targeted oncology company navigating new territory in patient-directed cancer treatment, today announced that it will participate in an oral presentation highlighting the company’s novel TEAD inhibitor, IK-930, at the American Association for Cancer Research (AACR) 2022 Annual Meeting.
Dr. Jeff Ecsedy, Ikena’s Chief Development Officer, will present data supporting the potential of IK-930 as a clinical agent during a minisymposium on experimental and molecular cancer therapeutics. Further details can be found below. The 2022 AACR Annual Meeting will be held April 8-13, 2022 in New Orleans, Louisiana. For more information on AACR and how to register, visit the website.
| Presentation details: | |
| Abstract Title: IK-930 is a novel TEAD inhibitor for the treatment of cancers harboring mutations in the Hippo signal transduction pathway Abstract Number: 2156 Presenter: Dr. Jeff Ecsedy | |
| Oral Presentation: Minisymposium, Experimental and Molecular Therapeutics Session Title: Emerging New Anticancer Agents Session Date/Time: Monday, April 11, 2022 - 2:30-4:30pm CT |
IK-930 is an oral, selective TEAD inhibitor targeting the Hippo signaling pathway. IK-930 binds to TEAD transcription factors and prevents transcription of multiple genes that drive cancer progression. By targeting the Hippo pathway, a key driver of cancer pathogenesis that is genetically altered in approximately 10% of all cancer types, IK-930 could have a differentiating impact across many cancers with high unmet need. Ikena is advancing IK-930 both as a monotherapy in patients with Hippo pathway mutated cancers and in combination with other approved targeted therapies to combat therapeutic resistance. IK-930 is currently being studied in a Phase 1 clinical trial as a monotherapy in patients with advanced solid tumors with or without gene alterations in the Hippo pathway, including NF2-deficient malignant mesothelioma, Epithelial Hemangioendothelioma (EHE) with documented TAZ/CAMTA1 fusion genes as well as other solid tumors with either NF2 deficiency or with YAP/TAZ genetic fusions (ClinicalTrials.gov Identifier: NCT05228015).
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