Full Press Release Details
InflaRx Opens New Research Facility in Ann
R&D activities will focus on proprietary
Site will be overseen by InflaRx Chief
Jena, Germany, 5 June 2018 -
InflaRx N.V. (Nasdaq: IFRX), a biopharmaceutical company developing innovative therapeutics to treat life-threatening
inflammatory diseases by targeting the complement system, a key component of the innate immune system, announced they have
opened a new research facility in Ann Arbor, Michigan, in the United States. The facility will be part of InflaRx
Pharmaceuticals Inc., a wholly owned US subsidiary of the InflaRx N.V. group, and operations will serve to further develop
and extend the Company's unique complement system-based therapeutics.
"At InflaRx, our primary focus is
to discover and develop complement-based therapeutics that can change the way inflammatory diseases are treated by providing innovative
solutions for patients with currently unmet medical needs," said Prof. Niels Riedemann, MD, Chief Executive Officer of InflaRx.
"The opening of InflaRx's new research site in Ann Arbor, the city where our co-founder and CSO, Renfeng Guo, and I
met and conducted our post-graduate studies researching the complement system, highlights the Company's strong connection
to cutting edge science and dedication to innovation."
InflaRx Chief Scientific Officer, Dr. Renfeng
Guo commented: "The Company's return to its scientific origins in Ann Arbor by opening this research facility is a
significant milestone for InflaRx that will afford us significant advantages as we focus on our mission of discovering and developing
superior treatments for inflammatory conditions. I am thrilled to have the opportunity to drive the site's operations and
look forward to taking full advantage of our new capabilities as we accelerate and broaden our pipeline."
Following InflaRx's successful initial
public offering on the Nasdaq exchange in November of last year and the recent successful follow-on offering, the opening of this
research facility represents the continued growth of the Company's presence in the US. The opening comes at a time when the
Company's lead candidate, IFX-1 is advancing through clinical trials with phase 2B data for its lead indication, hidradenitis
suppurativa, expected in the first half of 2019.
IFX-1 is a first-in-class monoclonal anti-complement
factor C5a antibody, which highly and effectively blocks the biological activity of C5a and demonstrates high selectivity towards
its target in human blood. Thus, IFX-1 leaves the formation of the membrane attack complex (C5b-9) intact as an important defense
mechanism, which is not the case for molecules blocking the cleavage of C5. IFX-1 has demonstrated
control of the inflammatory response driven
tissue and organ damage by specifically blocking C5a as a key "amplifier" of this response in pre-clinical studies.
IFX-1 is the first monoclonal anti-C5a antibody introduced into clinical development that has, to date, successfully completed
three clinical Phase II studies. In total, more than 150 patients have so far been treated with IFX-1, which was well tolerated.
IFX-1 is currently being developed for different inflammatory indications.
InflaRx (Nasdaq: IFRX) is a clinical-stage
biopharmaceutical company focused on applying its proprietary anti-C5a technology to discover and develop first-in-class, potent
and specific inhibitors of C5a. Complement C5a is a powerful inflammatory mediator involved in the progression of a wide variety
of autoimmune and other inflammatory diseases. InflaRx was founded in 2007 and has offices in Jena and Munich, Germany. InflaRx
is listed on the Nasdaq Global Select Market in the United States under the trading symbol "IFRX". For further information
please visit www.inflarx.com.
Prof. Dr. Niels C. Riedemann, CEO
LifeSci Public Relations
Matt Middleman, M.D.
Katja Arnold, Andreas Jungfer
FORWARD LOOKING STATEMENTS
release contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements,
which are often indicated by terms such as "may," "will," "should," "expect,"
"plan," "anticipate," "could," "intend," "target," "project,"
"estimate," "believe," "estimate," "predict," "potential" or "continue"
and similar expressions. Forward-looking statements appear in a number of places throughout this release and may include statements
regarding our intentions, beliefs, projections, outlook, analyses and current expectations concerning, among other things, our
ongoing and planned preclinical development and clinical trials, the timing of and our ability to make regulatory filings and
obtain and maintain regulatory approvals for our product candidates, our intellectual property position, our ability to develop
commercial functions, expectations regarding clinical trial data, our results of operations, cash needs, financial condition,
liquidity, prospects, future transactions, growth and strategies, the industry in which we operate, the trends that may affect
the industry or us and the risks uncertainties and other factors described under the heading "Risk Factors" in InflaRx's
periodic filings with the Securities and Exchange Commission. These statements speak only as of the date of this press release
and involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance
or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking
statements. Given these risks, uncertainties and other factors, you should not place undue reliance on these forward-looking statements,
and we assume no obligation to update these forward-looking statements, even if new information becomes available in the future,
except as required by law.