Integra LifeSciences Announces Amendment and Extension of Credit Facility PLAINSBORO, New Jersey /

LifeSciences Announces Amendment and Extension of Credit Facility

PLAINSBORO, New Jersey / May 7, 2018 Integra LifeSciences Holdings

Corporation (NASDAQ: IART), a leading global medical technology company, today announced that it has amended and extended its credit facility with a bank group led by Bank of America, N.A.

The overall size of the credit facility remains at $2.2 billion and consists of a revolving line of credit of $1.3 billion and a $900 million

term loan. The new terms include a decrease in applicable interest rates and commitment fees, and extends the maturity of the credit facility to May 3, 2023.

We are pleased to announce the two-year extension of our credit facility with improved pricing, said Glenn

Coleman, chief financial officer, Integra LifeSciences. With these new terms, we have strengthened our balance sheet and increased our flexibility to pursue our long-term revenue growth and profitability strategy. We appreciate the continued

support and commitment from our lending group.

Borrowings from the new revolving facility will also be used to cover fees and expenses incurred in

connection with the credit facility, and for general corporate purposes.

About Integra LifeSciences

Integra LifeSciences is a global leader in regenerative technologies, neurosurgical and extremity orthopedic solutions dedicated to limiting uncertainty for

clinicians, so they can focus on providing the best patient care. Integra offers a comprehensive portfolio of high quality, leadership brands that include AmnioExcel , Bactiseal , Cadence , CertasTM,

Codman , CUSA , DuraGen ,

DuraSeal , ICP Express , Integra , MediHoney , MicroFrance , PriMatrix , Salto Talaris , SurgiMend , TCC-EZ , Titan and

VersaTru . For the latest news and information about Integra and its brands, please visit www.integralife.com.

contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements involve risks and uncertainties that could cause actual results to differ from predicted results.

Forward-looking factors that may be discussed include, but are not limited to, future financial performance, new product development, governmental approvals, market potential and resulting sales as well as potential therapeutic applications, and

additional acquisitions. These risks and uncertainties include market conditions and other factors beyond the Company s control and the economic, competitive, governmental, technological and other factors identified under the heading Risk

Factors included in item 1A of Integra s Annual Report on Form 10-K for the year ended December 31, 2017 and information contained in subsequent filings with the Securities and Exchange

Commission could affect actual results. These forward-looking statements are made only as the date thereof, and the Company undertakes no obligation to update or revise the forward-looking statements, whether as a result of new information,

future events or otherwise.

Investor Relations Contacts:

Vice President, Treasurer & Investor

Director, Investor Relations

Senior Director, Global Corporate Communications