Harrow Enters into Commercialization Agreement with Samsung Bioepis for Ophthalmology Biosimilars Portfolio in the United States Harrow to assume full commercial responsibility for BYOOVIZ and OPUVIZ by the end of 2025

Enters into Commercialization Agreement with Samsung Bioepis

Ophthalmology Biosimilars Portfolio in the United States

to assume full commercial responsibility for BYOOVIZ and OPUVIZ by the end of 2025

Tenn., July 17, 2025 - Harrow (Nasdaq: HROW), a leading North American eyecare pharmaceutical company, today announced that it

has entered into a definitive agreement with Samsung Bioepis Co. Ltd. (hereafter "Samsung Bioepis") to secure the exclusive

U.S. commercial rights to the ophthalmology biosimilar portfolio of Samsung Bioepis -

BYOOVIZ (ranibizumab-nuna), an FDA-approved biosimilar referencing LUCENTISi (ranibizumab), and OPUVIZ

(aflibercept-yszy), an FDA-approved biosimilar referencing EYLEAii (aflibercept) -

two of the most widely used anti-VEGF therapies for retinal diseases.

has been commercialized by Biogen in the U.S. since its initial launch in June 2022. In October 2024, Biogen notified Samsung Bioepis

of their decision to terminate the 2019 Development and Commercialization Agreement within the U.S. and Canada. Samsung Bioepis has been

closely working with Biogen on the transfer of commercialization rights for BYOOVIZ and OPUVIZ back to Samsung Bioepis in these regions.

Harrow will assume full responsibility for commercialization of BYOOVIZ in the U.S. upon completion of the transition of commercial rights

from Biogen back to Samsung Bioepis. The transition is expected to be completed by the end of 2025.

strategic acquisition enhances Harrow's position as the leading full-spectrum ophthalmic pharmaceuticals provider in the U.S.,

expands its pipeline with high-value biosimilars for sight-threatening retinal diseases, and reinforces its commitment to delivering

value-oriented innovation to the U.S. eyecare market.

transformational acquisition marks a pivotal moment for Harrow and reinforces our commitment to delivering innovation, accessibility,

and value to the U.S. ophthalmology community," said Mark L. Baum, Chairman and Chief Executive Officer of Harrow. "We are

excited to leverage our growing commercial presence within the retina specialist community, built over the past year, and partner with

Samsung Bioepis, globally recognized for its scientific excellence in biologics and biosimilars. These ophthalmic assets are among the

most highly regarded in the market, and we are looking forward to bringing these products to U.S. physicians and patients."

is committed to reshaping the Wet AMD treatment landscape by offering an FDA-approved, on-label, and affordable alternative to existing

anti-VEGF therapies. The market is dominated by EYLEA, LUCENTIS, VABYSMO, and compounded Avastin, which continues to be used off-label

due to its low cost, despite not being formulated or approved for ocular administration. Current anti-VEGF therapies are among the most

expensive drug categories covered under Medicare Part B, with annual spending in the U.S. exceeding $4.2 billioniv. Harrow's

acquisition of these products has the potential to substantially lower the financial burden on Medicare and commercial plans, while improving

access and affordability for patients.

BYOOVIZ (ranibizumab-nuna)

(ranibizumab-nuna) injection, for intravitreal use.

(ranibizumab-nuna) is biosimilar to LUCENTIS (ranibizumab injection).

a vascular endothelial growth factor (VEGF) inhibitor, is indicated for the treatment of patients with:

(Wet) Age-Related Macular Degeneration (AMD)

Edema Following Retinal Vein Occlusion (RVO)

Choroidal Neovascularization (mCNV)

Important Safety Information

and retinal detachments may occur following intravitreal injections. Patients should be monitored following the injection.

in intraocular pressure (IOP) have been noted both pre- and post-intravitreal injection.

is a potential risk of arterial thromboembolic events following intravitreal use of VEGF inhibitors.

most common adverse reactions (reported more frequently in ranibizumab treated subjects than control subjects) are conjunctival hemorrhage,

eye pain, vitreous floaters, and increased IOP.

see Prescribing Information for BYOOVIZ (ranibizumab-nuna) HERE.

OPUVIZ (aflibercept-yszy)

(aflibercept-yszy) injection, for intravitreal use.

(aflibercept-yszy) is biosimilar to EYLEA (aflibercept).

is a vascular endothelial growth factor (VEGF) inhibitor, indicated for the treatment of patients with:

(Wet) Age-Related Macular Degeneration (AMD)

Edema Following Retinal Vein Occlusion (RVO)

Important Safety Information

retinal detachments, and retinal vasculitis with or without occlusion may occur following intravitreal injections. Patients and/or caregivers

should be instructed to report any signs and/or symptoms suggestive of endophthalmitis, retinal detachment, or retinal vasculitis without

delay and should be managed appropriately.

in intraocular pressure have been seen within 60 minutes of an intravitreal injection.

is a potential risk of arterial thromboembolic events following intravitreal use of VEGF inhibitors.

most common adverse reactions ( 5%) reported in patients receiving aflibercept were conjunctival hemorrhage, eye pain, cataract, vitreous

detachment, vitreous floaters, and intraocular pressure increased.

see Prescribing Information for OPUVIZ (aflibercept-yszy) HERE.

Inc. (Nasdaq: HROW) is a leading eyecare pharmaceutical company engaged in the discovery, development, and commercialization of innovative

ophthalmic pharmaceutical products for the North American market. Harrow helps eyecare professionals preserve the gift of sight by making

its portfolio of pharmaceutical products accessible and affordable to millions of patients each year. For more information about Harrow,

please visit harrow.com.

press release contains "forward-looking statements" within the meaning of the U.S. Private Securities Litigation Reform Act

of 1995. Any statements in this release that are not historical facts may be considered such "forward-looking statements."

Forward-looking statements are based on management's current expectations and are subject to risks and uncertainties which may

cause results to differ materially and adversely from the statements contained herein. Some of the potential risks and uncertainties

that could cause actual results to differ from those predicted include, among others, risks related to: liquidity or results of operations;

our ability to successfully implement our business plan, develop and commercialize our products, product candidates and proprietary formulations

in a timely manner or at all, identify and acquire additional products, manage our pharmacy operations, service our debt, obtain financing

necessary to operate our business, recruit and retain qualified personnel, manage any growth we may experience and successfully realize

the benefits of our previous acquisitions and any other acquisitions and collaborative arrangements we may pursue; competition from pharmaceutical

companies, outsourcing facilities and pharmacies; general economic and business conditions, including inflation and supply chain challenges;

regulatory and legal risks, including litigation matters, and other uncertainties related to our pharmacy operations and the pharmacy

and pharmaceutical business in general; physician interest in and market acceptance of our current and any future formulations and compounding

pharmacies generally. These and additional risks and uncertainties are more fully described in Harrow's filings with the Securities

and Exchange Commission (SEC), including its Annual Report on Form 10-K for the year ended December 31, 2024, subsequent Quarterly Reports

on Form 10-Q, and other filings with the SEC. Such documents may be read free of charge on the SEC's web site at sec.gov.

Undue reliance should not be placed on forward-looking statements, which speak only as of the date they are made. Except as required

by law, Harrow undertakes no obligation to update any forward-looking statements to reflect new information, events, or circumstances

after the date they are made, or to reflect the occurrence of unanticipated events.