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Genmab Announces Net Sales of DARZALEX® (daratumumab) for 2025

Key Takeaway: Genmab A/S announced that worldwide net sales of DARZALEX (daratumumab) reached USD 14,351 million in 2025, with significant contributions from both U.S. and international markets. The company receives royalties from these sales under its exclusive license agreement with Johnson & Johnson. Genmab is focused on developing innovative antibody medicines and has a strong pipeline of late-stage clinical programs.
Price reaction · baseline $31.33 (2026-01-20 close) · hit pre-market · clean, no other GMAB news in the window
day 0 close
+5.2%
day 1
+5.6%
day 3 · peak
+6.8%

Market Sentiment Analysis

POSITIVE FACTORS

  • Worldwide net sales of DARZALEX reached USD 14,351 million in 2025.
  • Sales in the U.S. amounted to USD 8,266 million, indicating strong market performance.
  • Genmab continues to advance a robust late-stage clinical pipeline.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+17%
120-day peak, hindsight
Typical move
1.4%
average across 7 past catalysts
Lead asset
Petosemtamab
Phase 3 · Colorectal Cancer

Full Press Release Details

Company Announcement
COPENHAGEN, Denmark; January 21, 2026 –Genmab A/S(Nasdaq: GMAB) announced today that worldwide net trade sales of DARZALEX®(daratumumab), including sales of the subcutaneous (SC) product (daratumumab and hyaluronidase-fihj, sold under the tradename DARZALEXFASPRO®in the U.S.), as reported by J&J were USD 14,351 million in 2025.Net trade sales were USD 8,266 million in the U.S. and USD 6,085 million in the rest of the world. Genmab receives royalties on the worldwide net sales of DARZALEX, both the intravenous and SC products, under the exclusive worldwide license to J&J to develop, manufacture and commercialize daratumumab.
About GenmabGenmab is an international biotechnology company dedicated to improving the lives of people with cancer and other serious diseases through innovative antibody medicines. For over 25 years, its passionate, innovative and collaborative team has advanced a broad range of antibody-based therapeutic formats, including bispecific antibodies, antibody–drug conjugates (ADCs), immune-modulating antibodies and other next-generation modalities. Genmab’s science powers eight approved antibody medicines, and the company is advancing a strong late-stage clinical pipeline, including wholly owned programs, with the goal of delivering transformative medicines to patients.
Established in 1999, Genmab is headquartered in Copenhagen, Denmark, with international presence across North America, Europe and Asia Pacific. For more information, please visitGenmab.comand follow us onLinkedInandX.Contact:Marisol Peron, Senior Vice President, Global Communications & Corporate AffairsT: +1 609 524 0065; E:mmp@genmab.com
Andrew Carlsen, Vice President, Head of Investor RelationsT: +45 3377 9558; E:acn@genmab.comThis Company Announcement contains forward looking statements. The words “believe,” “expect,” “anticipate,” “intend” and “plan” and similar expressions identify forward looking statements. Actual results or performance may differ materially from any future results or performance expressed or implied by such statements. The important factors that could cause our actual results or performance to differ materially include, among others, risks associated with preclinical and clinical development of products, uncertainties related to the outcome and conduct of clinical trials including unforeseen safety issues, uncertainties related to product manufacturing, the lack of market acceptance of our products, our inability to manage growth, the competitive environment in relation to our business area and markets, our inability to attract and retain suitably qualified personnel, the unenforceability or lack of protection of our patents and proprietary rights, our relationships with affiliated entities, changes and developments in technology which may render our products or technologies obsolete, and other factors. For a further discussion of these risks, please refer to the risk management sections in Genmab’s most recent financial reports, which are available onwww.genmab.comand the risk factors included in Genmab’s most recent Annual Report on Form 20-F and other filingswith the U.S. Securities and Exchange Commission (SEC), which are available atwww.sec.gov. Genmab does not undertake any obligation to update or revise forward looking statements in this Company Announcement nor to confirm such statements to reflect subsequent events or circumstances after the date made or in relation to actual results, unless required by law.Genmab A/S and/or its subsidiaries own the following trademarks: Genmab®; the Y-shaped Genmab logo®; Genmab in combination with the Y-shaped Genmab logo®; HuMax®; DuoBody®; HexaBody®; DuoHexaBody®, HexElect®and KYSO®. DARZALEX®and DARZALEX FASPRO®are trademarks of Johnson & Johnson.
Company Announcement no. 02CVR no. 2102 3884LEI Code 529900MTJPDPE4MHJ122
Genmab A/SCarl Jacobsens Vej 302500 ValbyDenmark

Frequently Asked Questions

What were the total net sales of DARZALEX in 2025?

The total worldwide net sales of DARZALEX in 2025 were USD 14,351 million.

How much did DARZALEX sell in the U.S. market?

In the U.S., DARZALEX sales amounted to USD 8,266 million.

What is Genmab's role in DARZALEX sales?

Genmab receives royalties on the worldwide net sales of DARZALEX under its license with J&J.

What is Genmab's focus as a biotechnology company?

Genmab is dedicated to developing innovative antibody medicines for cancer and serious diseases.

Last updated: Jan 21, 2026