Full Press Release Details
Product Sales Excluding Veklury Increased 8%Year-Over-Year to $6.8 billion
Biktarvy Sales Increased7% Year-Over-Year to $3.4 billion
FOSTER CITY, Calif.--(BUSINESS WIRE)--#Earnings--Gilead Sciences, Inc. (Nasdaq: GILD) announced today its results of operations for the first quarter 2026.
“Gilead teams have delivered another strong quarter with 8% year-over-year growth in our base business and 10% growth in HIV, supported by the successful launch of Yeztugo. We have raised our full year revenue guidance as a reflection of our performance," said Daniel O’Day, Gilead’s Chairman and Chief Executive Officer. “Building on the strongest pipeline in Gilead’s history, we are adding potentially best-in-disease assets and platforms in oncology and inflammation from our acquisitions of Arcellx, Ouro Medicines and Tubulis. With up to four potential launches and five Phase 3 updates anticipated in 2026, Gilead is well-positioned for sustained growth in the near and long term.”
First Quarter 2026 Financial Results
First Quarter 2026 Product Sales
Total first quarter 2026 product sales increased 5% to $6.9 billion compared to the same period in 2025. Total first quarter 2026 product sales excluding Veklury increased 8% to $6.8 billion compared to the same period in 2025, primarily due to higher sales of HIV products, Trodelvy and Livdelzi, partially offset by lower sales of HCV and Cell Therapy products.
HIVproduct sales increased 10% to $5.0 billion in the first quarter 2026 compared to the same period in 2025, primarily driven by higher demand and average realized price, partially offset by unfavorable inventory dynamics.
TheLiver Diseaseportfolio sales increased 1% to $767 million in the first quarter 2026 compared to the same period in 2025, primarily reflecting higher demand for Livdelzi, partially offset by unfavorable inventory dynamics and lower sales for HCV products.
Veklurysales decreased 52% to $144 millionin the first quarter 2026 compared to the same period in 2025, primarily driven by lower rates of COVID-19-related hospitalizations.
Cell Therapyproduct sales decreased 12% to $407 million in the first quarter 2026 compared to the same period in 2025, reflecting ongoing competitive headwinds.
Trodelvy®(sacituzumab govitecan-hziy) sales increased 37% to $402 million in the first quarter 2026 compared to the same period in 2025, primarily driven by higher demand, favorable inventory dynamics and higher average realized price.
First Quarter 2026 Product Gross Margin, Operating Expenses and Effective Tax Rate
Guidance and Outlook
For the full year 2026, Gilead now expects:
| (in millions, except per share amounts) | May 7, 2026 Guidance | Comparison to February 10, 2026 Guidance | ||||||||
| Low End | High End | |||||||||
| Product sales | $ | 30,000 | $ | 30,400 | Previously $29,600 to $30,000 | |||||
| Product sales excluding Veklury | $ | 29,400 | $ | 29,800 | Previously $29,000 to $29,400 | |||||
| Veklury | $ | 600 | $ | 600 | Unchanged | |||||
| Diluted (loss) earnings per share | $ | (3.25 | ) | $ | (2.85 | ) | Previously $6.75 to $7.15 | |||
| Non-GAAP diluted (loss) earnings per share | $ | (1.05 | ) | $ | (0.65 | ) | Previously $8.45 to $8.85 |
As compared to our February guidance, our updated full year 2026 GAAP and non-GAAP diluted earnings per share guidance was reduced by approximately $9.50 due to the anticipated acquired IPR&D charges of $11.5 billion as well as financing costs related to the Arcellx, Inc. (“Arcellx”), Ouro Medicines, LLC (“Ouro”), and Tubulis GmbH (“Tubulis”) transactions discussed further below.
Additional information and a reconciliation between GAAP and non-GAAP financial information for the 2026 guidance is provided in the accompanying tables. The financial guidance is subject to a number of risks and uncertainties. See the Forward-Looking Statements section below.
Key Updates Since Our Last Quarterly Release
Virology
Oncology
Inflammation
Corporate
Certain amounts and percentages in this press release may not sum or recalculate due to rounding.
Conference Call
At 1:30 p.m. Pacific Time today, Gilead will host a conference call to discuss Gilead’s results. A live webcast will be available onhttp://investors.gilead.comand will be archived onwww.gilead.comfor one year.
Non-GAAP Financial Information
The information presented in this document has been prepared in accordance with U.S. generally accepted accounting principles (“GAAP”), unless otherwise noted as non-GAAP. Management believes non-GAAP information is useful for investors, when considered in conjunction with Gilead’s GAAP financial information, because management uses such information internally for its operating, budgeting and financial planning purposes. Non-GAAP information is not prepared under a comprehensive set of accounting rules and should only be used to supplement an understanding of Gilead’s operating results as reported under GAAP. Non-GAAP financial information generally excludes acquisition-related expenses including amortization of acquired intangible assets and other items that are considered unusual or not representative of underlying trends of Gilead’s business, fair value adjustments of equity securities, the related tax charges or benefits associated with such exclusions and other discrete tax charges or benefits not representative of underlying trends such as changes in tax laws, transfers of intangible assets between certain legal entities, and effects of legal entity restructurings. Although Gilead consistently excludes the amortization of acquired intangible assets from the non-GAAP financial information, management believes that it is important for investors to understand that such intangible assets were recorded as part of acquisitions and contribute to ongoing revenue generation.Non-GAAP measures may be defined and calculated differently by other companies in the same industry. Reconciliations of the non-GAAP financial measures to the most directly comparable GAAP financial measures are provided in the accompanying tables.
About Gilead Sciences
Gilead Sciences, Inc. is a biopharmaceutical company that has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a healthier world for all people. The company is committed to advancing innovative medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis, COVID-19, cancer and inflammation. Gilead operates in more than 35 countries worldwide, with headquarters in Foster City, California.
Forward-Looking Statements
Statements included in this press release that are not historical in nature are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Gilead cautions readers that forward-looking statements are subject to certain risks and uncertainties that could cause actual results to differ materially. These risks and uncertainties include those relating to: Gilead’s ability to achieve its full year 2026 financial guidance, including as a result of the uncertainty of the amount and timing of Veklury revenues, the impact from Medicare Part D pricing reform in the Inflation Reduction Act, the expiration of subsidies related to the Affordable Care Act, our most-favored-nation pricing agreement with the U.S. government, changes in U.S. regulatory or legislative policies, and changes in U.S. trade policies, including tariffs; Gilead’s ability to make progress on any of its long-term ambitions or priorities laid out in its corporate strategy; Gilead’s ability to accelerate or sustain revenues for its virology, oncology, inflammation and other programs; Gilead’s ability to realize the potential benefits of acquisitions, collaborations or licensing arrangements, including the arrangements with Arcellx, Galapagos, Genhouse, Ouro, PEPFAR, The Global Fund, and Tubulis; the possibility that various closing conditions for any proposed acquisitions, collaborations or licensing arrangements may not be satisfied or waived, including that a governmental entity may prohibit, delay or refuse to grant approval for the consummation of any such transaction; the risk that Gilead’s U.S. manufacturing and R&D investment may not achieve their intended benefits; patent protection and estimated loss of exclusivity for our products and product candidates; Gilead’s ability to initiate, progress or complete clinical trials within currently anticipated timeframes or at all, the possibility of unfavorable results from ongoing and additional clinical trials, including those involving Tecartus, bictegravir, and lenacapavir, (such as ARTISTRY-1, ARTISTRY-2, and ZUMA-2), and the risk that safety and efficacy data from clinical trials may not warrant further development of Gilead’s product candidates or the product candidates of Gilead’s strategic partners; Gilead’s ability to resolve the issues cited by the FDA in pending clinical holds to the satisfaction of the FDA and the risk that FDA may not remove such clinical holds, in whole or in part, in a timely manner or at all; Gilead’s ability to submit new drug applications for new product candidates or expanded indications in the currently anticipated timelines; Gilead’s ability to receive or maintain regulatory approvals in a timely manner or at all, and the risk that any such approvals, if granted, may be subject to significant limitations on use and may be subject to withdrawal or other adverse actions by the applicable regulatory authority, including those involving BIC/LEN and anito-cel; Gilead’s ability to successfully commercialize its products; the risk of potential disruptions to the manufacturing and supply chain of Gilead’s products; pricing and reimbursement pressures from government agencies and other third parties, including required rebates and other discounts; a larger than anticipated shift in payer mix to more highly discounted payer segments; market share and price erosion caused by the introduction of generic versions of Gilead products; the risk that physicians and patients may not see advantages of Gilead’s products over other therapies and may therefore be reluctant to prescribe the products, including Tecartus; Gilead’s ability to effectively manage the access strategy relating to lenacapavir for HIV PrEP, subject to necessary regulatory approvals; and other risks identified from time to time in Gilead’s reports filed with the SEC, including annual reports on Form 10-K, quarterly reports on Form 10-Q and current reports on Form 8-K. In addition, Gilead makes estimates and judgments that affect the reported amounts of assets, liabilities, revenues and expenses and related disclosures. Gilead bases its estimates on historical experience and on various other market specific and other relevant assumptions that it believes to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. There may be other factors of which Gilead is not currently aware that may affect matters discussed in the forward-looking statements and may also cause actual results to differ significantly from these estimates. Further, results for the quarter ended March 31, 2026 are not necessarily indicative of operating results for any future periods. Gilead directs readers to its press releases, annual reports on Form 10-K, quarterly reports on Form 10-Q and other subsequent disclosure documents filed with the SEC. Gilead claims the protection of the Safe Harbor contained in the Private Securities Litigation Reform Act of 1995 for forward-looking statements.
The reader is cautioned that forward-looking statements are not guarantees of future performance and is cautioned not to place undue reliance on these forward-looking statements. All forward-looking statements are based on information currently available to Gilead and Gilead assumes no obligation to update or supplement any such forward-looking statements other than as required by law. Any forward-looking statements speak only as of the date hereof or as of the dates indicated in the statements.
Additional information is available on our Investor Relations website,https://investors.gilead.com. Among other things, an estimate of Acquired IPR&D expenses is expected to be made available on the Quarterly Results page within the first ten (10) days after the end of each quarter.
# # #
Gilead owns or has rights to various trademarks, copyrights and trade names used in its business, including the following: GILEAD®, GILEAD SCIENCES®, KITE®, AMBISOME®, ATRIPLA®, BIKTARVY®, CAYSTON®, COMPLERA®, DESCOVY®, DESCOVY FOR PREP®, EMTRIVA®, EPCLUSA®, EVIPLERA®, GENVOYA®, HARVONI®, HEPCLUDEX®, HEPSERA®, JYSELECA®, LIVDELZI®/LYVDELZI®, LETAIRIS®, ODEFSEY®, SOVALDI®, STRIBILD®, SUNLENCA®, TECARTUS®, TRODELVY®, TRUVADA®, TRUVADA FOR PREP®, TYBOST®, VEKLURY®, VEMLIDY®, VIREAD®, VOSEVI®, YESCARTA®, YEZTUGO®/YEYTUO® and ZYDELIG®. Other trademarks and trade names are the property of their respective owners.
For more information on Gilead Sciences, Inc., please visitwww.gilead.comor call the Gilead Public Affairs Department at 1-800-GILEAD-5 (1-800-445-3235).
| GILEAD SCIENCES, INC. | ||||||||
| CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS | ||||||||
| (unaudited) | ||||||||
| Three Months Ended | ||||||||
| March 31, | ||||||||
| (in millions, except per share amounts) | 2026 | 2025 | ||||||
| Revenues: | ||||||||
| Product sales | $ | 6,946 | $ | 6,613 | ||||
| Royalty, contract and other revenues | 14 | 54 | ||||||
| Total revenues | 6,960 | 6,667 | ||||||
| Costs and expenses: | ||||||||
| Cost of goods sold | 1,445 | 1,540 | ||||||
| Research and development expenses | 1,372 | 1,379 | ||||||
| Acquired in-process research and development expenses | 107 | 253 | ||||||
| Selling, general and administrative expenses | 1,451 | 1,258 | ||||||
| Total costs and expenses | 4,374 | 4,430 | ||||||
| Operating income | 2,586 | 2,237 | ||||||
| Interest expense | 240 | 260 | ||||||
| Other (income) expense, net | (235 | ) | 328 | |||||
| Income before income taxes | 2,580 | 1,649 | ||||||
| Income tax expense | 559 | 334 | ||||||
| Net income | $ | 2,021 | $ | 1,315 | ||||
| Basic earnings per share | $ | 1.63 | $ | 1.06 | ||||
| Diluted earnings per share | $ | 1.61 | $ | 1.04 | ||||
| Shares used in basic earnings per share calculation | 1,242 | 1,246 | ||||||
| Shares used in diluted earnings per share calculation | 1,254 | 1,259 | ||||||
| Supplemental Information: | ||||||||
| Cash dividends declared per share | $ | 0.82 | $ | 0.79 | ||||
| Product gross margin | 79.2 | % | 76.7 | % | ||||
| Research and development expenses as a % of revenues | 19.7 | % | 20.7 | % | ||||
| Selling, general and administrative expenses as a % of revenues | 20.9 | % | 18.9 | % | ||||
| Operating margin | 37.2 | % | 33.6 | % | ||||
| Effective tax rate | 21.7 | % | 20.2 | % |
| GILEAD SCIENCES, INC. | |||||||||
| TOTAL REVENUE SUMMARY | |||||||||
| (unaudited) | |||||||||
| Three Months Ended | |||||||||
| March 31, | |||||||||
| (in millions, except percentages) | 2026 | 2025 | Change | ||||||
| Product sales: | |||||||||
| HIV | $ | 5,030 | $ | 4,587 | 10 | % | |||
| Liver Disease | 767 | 758 | 1 | % | |||||
| Oncology | 810 | 757 | 7 | % | |||||
| Other | 196 | 209 | (6 | )% | |||||
| Total product sales excluding Veklury | 6,802 | 6,311 | 8 | % | |||||
| Veklury | 144 | 302 | (52 | )% | |||||
| Total product sales | 6,946 | 6,613 | 5 | % | |||||
| Royalty, contract and other revenues | 14 | 54 | (75 | )% | |||||
| Total revenues | $ | 6,960 | $ | 6,667 | 4 | % |
| GILEAD SCIENCES, INC. | |||||||||||
| NON-GAAP FINANCIAL INFORMATION(1) | |||||||||||
| (unaudited) | |||||||||||
| Three Months Ended | |||||||||||
| March 31, | |||||||||||
| (in millions, except percentages) | 2026 | 2025 | Change | ||||||||
| Non-GAAP: | |||||||||||
| Cost of goods sold | $ | 869 | $ | 961 | (10 | )% | |||||
| Research and development expenses | $ | 1,355 | $ | 1,338 | 1 | % | |||||
| Acquired IPR&D expenses | $ | 107 | $ | 253 | (58 | )% | |||||
| Selling, general and administrative expenses | $ | 1,363 | $ | 1,222 | 12 | % | |||||
| Other (income) expense, net | $ | (92 | ) | $ | (98 | ) | (6 | )% | |||
| Diluted earnings per share | $ | 2.03 | $ | 1.81 | 12 | % | |||||
| Shares used in non-GAAP diluted earnings per share calculation | 1,254 | 1,259 | — | % | |||||||
| Product gross margin | 87.5 | % | 85.5 | % | 202 bps | ||||||
| Research and development expenses as a % of revenues | 19.5 | % | 20.1 | % | -61 bps | ||||||
| Selling, general and administrative expenses as a % of revenues | 19.6 | % | 18.3 | % | 126 bps | ||||||
| Operating margin | 46.9 | % | 43.4 | % | 356 bps | ||||||
| Effective tax rate | 18.3 | % | 16.3 | % | 195 bps |
Investors:Jacquie Ross, CFAinvestor_relations@gilead.comMedia:Ashleigh Kosspublic_affairs@gilead.com