Recent Updates
Recently added Catalysts
GILD Positive Sentiment

Gilead to Acquire Investigational Oral IL-23R Inhibitor HCXT-2001, Strengthening Its Inflammation Pipeline in IBD

Key Takeaway: Gilead Sciences has announced a definitive agreement to acquire HCXT-2001, an oral IL-23R inhibitor, from PepStar Therapeutics. This investigational drug is designed to treat inflammatory bowel disease (IBD) and features an extended half-life. The acquisition aims to enhance Gilead's pipeline in inflammation treatments.

Market Sentiment Analysis

POSITIVE FACTORS

  • Gilead is expanding its inflammation pipeline.
  • HCXT-2001 offers a potentially differentiated approach.
  • The acquisition strengthens Gilead's position in IBD.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+29%
120-day peak, hindsight
Typical move
1.6%
average across 15 past catalysts
Lead asset
Lenacapavir
Phase 3 · Pre-Exposure Prophylaxis of HIV Infection

Full Press Release Details

FOSTER CITY, Calif.--(BUSINESS WIRE)--Gilead Sciences, Inc. (Nasdaq: GILD) today announced that it has entered into a definitive agreement to acquire an oral IL-23R inhibitor program, including lead asset HCXT-2001, from PepStar Therapeutics Limited, a privately held, clinical-stage biotechnology company. Key Highlights HCXT-2001 is an investigational, clinical-stage, oral, macrocyclic peptide inhibitor of IL-23R with an extended half-life, offering a potentially differentiated approach to oral

Frequently Asked Questions

What is HCXT-2001?

HCXT-2001 is an investigational oral IL-23R inhibitor for IBD.

Who is acquiring HCXT-2001?

Gilead Sciences is acquiring HCXT-2001 from PepStar Therapeutics.

What does the acquisition strengthen?

The acquisition strengthens Gilead's inflammation pipeline in IBD.

What type of drug is HCXT-2001?

HCXT-2001 is a macrocyclic peptide inhibitor with an extended half-life.

Last updated: Oct 22, 2026