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GH Research to Provide Update on Phase 2b Trial with GH001 in TRD Dublin, Ireland

Key Takeaway: GH Research PLC will hold a conference call on February 3, 2025, to update stakeholders on the Phase 2b trial of GH001 for treatment-resistant depression (TRD). The trial is randomized, double-blind, and placebo-controlled, aiming to provide insights into the efficacy of their novel treatment. Previous trials indicated that 87.5% of TRD patients achieved ultra-rapid remission with GH001, suggesting its transformative potential in this area.

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POSITIVE FACTORS

  • GH001 shows promise in achieving ultra-rapid remission for TRD.
  • Clinical activity from previous trials indicates potential efficacy.
  • GH Research is focused on innovative treatments for psychiatric disorders.

Full Press Release Details

Research to Provide Update on Phase 2b Trial with GH001 in TRD
Ireland, January 31, 2025 - GH Research PLC (Nasdaq: GHRS), a clinical-stage biopharmaceutical company dedicated to transforming
the treatment of psychiatric and neurological disorders, today announced that it will host a conference call and live webcast on Monday,
February 3, 2025, at 8.00 a.m. EST to provide an update on data from the randomized, double-blind, placebo-controlled Phase 2b trial
of GH001 in treatment-resistant depression (TRD).
access the conference call, please register in advance here. A live webcast of the call will be available under "Events & Presentations"
in the Investors section of GH Research PLC's website at ghres.com.
Research PLC is a clinical-stage biopharmaceutical company dedicated to transforming the treatment of psychiatric and neurological disorders.
GH Research PLC's initial focus is on developing its novel and proprietary mebufotenin therapies for the treatment of patients with treatment-resistant
lead product candidate, GH001, is formulated for mebufotenin administration via a proprietary inhalation approach. Based on the observed
clinical activity in our completed phase 1/2 GH001-TRD-102 trial, where 87.5% of patients with TRD achieved ultra-rapid remission with
our GH001 individualized single-day dosing regimen in the Phase 2 part of the trial, we believe that GH001 has the potential to change
the way TRD is treated today.

Frequently Asked Questions

What is GH Research PLC's focus?

GH Research PLC is focused on transforming treatments for psychiatric and neurological disorders.

When is the conference call for the Phase 2b trial update?

The conference call is scheduled for February 3, 2025, at 8:00 a.m. EST.

How can I access the conference call?

You can register in advance or watch the live webcast on GH Research PLC's website.

What was the result of the GH001-TRD-102 trial?

In the GH001-TRD-102 trial, 87.5% of patients achieved ultra-rapid remission.

What is GH001's administration method?

GH001 is administered through a proprietary inhalation approach.

Last updated: Jan 31, 2025