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Galectin Therapeutics to Present at the 2025 MASH-TAG Conference

Key Takeaway: Galectin Therapeutics, Inc. will present the top-line results of its NAVIGATE trial at the 2025 MASH-TAG Conference, focusing on patients with MASH cirrhosis and portal hypertension. The presentation will detail the effectiveness of belapectin, reporting a decrease in varices development among participants. Furthermore, Galectin's leadership plans to hold one-on-one meetings during the JP Morgan Healthcare Conference to engage with stakeholders about the trial results and future efforts. Belapectin, a drug targeting galectin-3, has received Fast Track designation from the FDA, highlighting its potential in treating chronic liver conditions.
Price reaction · baseline $1.13 (2025-01-08 close) · hit after-hours · 1 other GALT headline(s) in the window, move may be shared
day 0 close · peak
-2.7%

Market Sentiment Analysis

POSITIVE FACTORS

  • Galectin Therapeutics to present promising NAVIGATE trial results.
  • Top-line results indicate reduced incidence of varices development.
  • Executive leadership engaging with stakeholders during JP Morgan Conference.
  • Belapectin has Fast Track designation from the FDA.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+23%
120-day peak, hindsight
Typical move
22.4%
average across 5 past catalysts
Cash runway
~16 mo
Low dilution risk
Lead asset
GR-MD-02
Phase 2 · Nonalcoholic Steatohepatitis

Full Press Release Details

NORCROSS, Ga., Jan. 10, 2025 (GLOBE NEWSWIRE) -- Galectin Therapeutics, Inc. (NASDAQ: GALT), the leading developer of therapeutics that target galectin proteins, today announced that the top-line results of the NAVIGATE trial in patients with MASH cirrhosis and portal hypertension will be presented during the 2025 MASH-TAG Conference, being held January 9-11, 2025 in Park City, Utah. Additionally, Company’s executive leadership will be hosting one-on-one meetings in San Franscico January 13-16, 2025, during JP Morgan Healthcare Conference and is looking forward to engaging external stakeholders on NAVIGATE topline results and discussing next steps for the belapectin program.
Presentation details
Title: Belapectin administered at 2mg/kg/LBW for 18 months reduced the incidence of varices development in patients with MASH cirrhosis and portal hypertension: Top line results from the NAVIGATE trial
Presenter: Naim Alkhouri, M.D., Chief Medical Officer, Arizona Liver Health, Chandler, AZ
Format: Oral presentation
Session: Deep Dive into Incretin and Endocrine Based Therapies
Date & Time: January 10, 2025 at 11:25 AM MST
About Galectin Therapeutics
Galectin Therapeutics is dedicated to developing novel therapies to improve the lives of patients with chronic liver disease and cancer. Galectin’s lead drug belapectin is a carbohydrate-based drug that inhibits the galectin-3 protein, which is directly involved in multiple inflammatory, fibrotic, and malignant diseases, for which it has Fast Track designation by the U.S. Food and Drug Administration. The lead development program is in metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis, or NASH) with cirrhosis, the most advanced form of MASH-related fibrosis. Liver cirrhosis is one of the most pressing medical needs and a significant drug development opportunity. Additional development programs are in treatment of combination immunotherapy for advanced head and neck cancers and other malignancies. Advancement of these additional clinical programs is largely dependent on finding a suitable partner. Galectin seeks to leverage extensive scientific and development expertise as well as established relationships with external sources to achieve cost-effective and efficient development. Additional information is available at www.galectintherapeutics.com.
Jack Callicutt, Chief Financial Officer
Investors Relations Contacts:
Galectin Therapeutics and its associated logo is a registered trademark of Galectin Therapeutics Inc. Belapectin is the USAN assigned name for Galectin Therapeutics’ galectin-3 inhibitor belapectin.

Frequently Asked Questions

What are the NAVIGATE trial results about?

The NAVIGATE trial results indicate that belapectin reduced the incidence of varices in MASH cirrhosis patients.

When and where will the NAVIGATE trial results be presented?

The results will be presented on January 10, 2025, at the MASH-TAG Conference in Park City, Utah.

Who is presenting the NAVIGATE trial results?

Dr. Naim Alkhouri, Chief Medical Officer of Arizona Liver Health, will present.

What is belapectin used for?

Belapectin is a galectin-3 inhibitor aimed at treating chronic liver disease and cancer.

How is Galectin Therapeutics advancing its drug programs?

Galectin seeks partnerships to enhance the development of its therapies, including belapectin.

Last updated: Jan 10, 2025