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CLASP II TR Trial Demonstrates Superior Clinical, Quality-of-Life Benefits With Edwards PASCAL System

Key Takeaway: Edwards Lifesciences announced that its PASCAL system for tricuspid repair outperformed medical therapy in the six-month primary endpoint of the CLASP II TR trial. The trial demonstrated a significant reduction in tricuspid regurgitation and improved health status, with these benefits maintained for one year. The results were shared at a major clinical conference.

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POSITIVE FACTORS

  • PASCAL system showed superiority over medical therapy.
  • Significant reduction in tricuspid regurgitation.
  • Substantial improvement in health status.
  • Benefits sustained through one year.

Full Press Release Details

SAN DIEGO--(BUSINESS WIRE)--Edwards Lifesciences Corporation (NYSE: EW) today announced that the PASCAL system for tricuspid repair demonstrated superiority compared to medical therapy alone for the six-month primary endpoint of the CLASP II TR trial. The evidence further showed significant reduction of tricuspid regurgitation (TR) and substantially improved health status, both sustained through one year. The data were presented during late-breaking clinical trial sessions at Transcatheter Cardi

Frequently Asked Questions

What is the PASCAL system?

The PASCAL system is designed for tricuspid repair.

What were the results of the CLASP II TR trial?

The trial showed superiority of PASCAL over medical therapy.

How long were the benefits sustained?

Benefits were sustained through one year.

What improvements did the PASCAL system provide?

It significantly reduced tricuspid regurgitation and improved health status.

Last updated: Nov 2, 2026