Full Press Release Details
Evaxion Biotech Completes Recruitment for Phase 1/2a Clinical Trial
Copenhagen, Denmark, March 7, 2022 - Evaxion Biotech A/S
(NASDAQ: EVAX), a clinical-stage biotechnology company specializing in the development of AI-driven immunotherapies, has now finalized
recruitment for Phase 1/2a clinical trial of EVX-02 in adjuvant melanoma patients.
The Company already conducts the successful EVX-01 program with clinical
testing in Australia, Europe and the US, where app. 100 patients suffering from malignant melanoma (metastasized skin cancer) will be
treated with EVX-01 therapy in combination with Keytruda from Merck. In the
EVX-02 program, Evaxion treats patients with adjuvant melanoma, meaning that their tumors have been successfully removed (surgically),
and in the study the focus of the therapy is to avoid relapse.
In the EVX-02 study encouraging preliminary findings around its potential
clinical benefit now allows Evaxion to accelerate the development program. Following the finalization of recruitment, Evaxion will advance
into a dedicated Phase 2b clinical trial using its patented DNA-based immunotherapy.
For the patients enrolled in the Phase 1/2a clinical trial, Evaxion's
proprietary PIONEERTM AI technology identified a sufficient number of mutations to design a personalized treatment and so far,
no serious side effects have been reported.
Lars Wegner, CEO of Evaxion, said:
"Completion of recruitment for the Phase 1/2a clinical trial
of EVX-02 is an important milestone, which supports our belief that the Evaxion approach is feasible. EVX-02 appears to be well tolerated
and shows encouraging signs as a treatment for adjuvant melanoma patients. The T-cell activation is promising, which allows us to take
data and insights from this clinical trial and move into a dedicated Phase 2 clinical trial."
About the EVX-02 Program:
Evaxion Biotech A/S is a clinical-stage AI-immunology platform
company decoding the human immune system to discover and develop novel immunotherapies to treat cancer, bacterial diseases and viral infections.
Based on its proprietary and scalable AI-immunology core technology, Evaxion is developing a broad pipeline of novel product candidates
which currently includes three patient-specific cancer immunotherapies.
For more information
LifeSci Advisors LLC
Source: Evaxion Biotech
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