Esperion Announces Proposed Public Offering of Common Stock

Esperion Announces Proposed Public Offering of Common Stock

ANN ARBOR, Mich., October 7, 2025 (GLOBE

NEWSWIRE) - Esperion Therapeutics, Inc. ("Esperion") (Nasdaq: ESPR), a commercial stage biopharmaceutical company

that focuses on developing and commercializing accessible, oral, once-daily, non-statin medicines for patients struggling with elevated

low-density lipoprotein cholesterol (LDL-C), today announced that it has commenced an underwritten public offering of shares of its common

stock. Esperion also intends to grant the underwriters a 30-day option to purchase up to an additional fifteen percent (15%) of the shares

of its common stock offered in the public offering. All of the shares of common stock in the proposed offering are to be sold by Esperion.

The proposed offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may

be completed, or as to the actual size or terms of the offering.

Piper Sandler & Co. and Cantor Fitzgerald &

Co. are acting as joint book-running managers for the proposed offering.

The shares of common stock are being offered by

Esperion pursuant to an effective shelf registration statement that was previously filed with the U.S. Securities and Exchange Commission

(SEC) on April 18, 2025 and declared effective by the SEC on April 29, 2025 (File No. 333-286631). The offering is being

made only by means of a written prospectus and prospectus supplement that form a part of the registration statement. A preliminary prospectus

supplement relating to and describing the terms of the offering will be filed with the SEC and will be available on the SEC's website

When available, copies of the preliminary prospectus

supplement relating to the offering may also be obtained from Piper Sandler & Co., Attention: Prospectus Department, 350 North

5th Street, Suite 1000, Minneapolis, Minnesota 55401 or by email at prospectus@psc.com; or Cantor Fitzgerald & Co., Attention:

Equity Capital Markets, 110 East 59th Street, 6th Floor, New York, New York 10022, or by email at prospectus@cantor.com.

The final terms of the offering will be disclosed

in a final prospectus supplement to be filed with the SEC.

This press release shall not constitute an offer

to sell or a solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction

in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any

such state or jurisdiction.

About Esperion Therapeutics

Esperion is a commercial stage biopharmaceutical

company focused on bringing new medicines to market that address unmet needs of patients and healthcare professionals. Esperion developed

and is commercializing the only U.S. Food and Drug Administration (FDA) approved oral, once-daily, non-statin medicines for patients who

are at risk for cardiovascular disease and are struggling with elevated low density lipoprotein cholesterol (LDL-C). These medications

are supported by the nearly 14,000 patient CLEAR Cardiovascular Outcomes Trial. Esperion continues to build on its success with its next

generation program which is focused on developing ATP citrate lyase inhibitors (ACLYi). New insights into the structure and function of

ACLYi fully enables rational drug design and the opportunity to develop highly potent and specific inhibitors with allosteric mechanisms.

Esperion continues to evolve into a leading global

biopharmaceutical company through commercial execution, international partnerships and collaborations and advancement of its pre-clinical

Forward-Looking Statements

This press release contains forward-looking statements

within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, implied and express

statements about Esperion's beliefs and expectations regarding: the timing and size of the proposed public offering, and the possibility

that the proposed offering will be completed on the anticipated terms or at all. The words "anticipate," "believe,"

"estimate," "expect," "intend," "may," "plan," "predict," "project,"

"suggest," "target," "potential," "will," "would," "could," "should,"

"continue," and similar words or expressions are intended to identify forward-looking statements, although not all forward-looking

statements contain these identifying words. Any express or implied statements contained in this press release that are not statements

of historical fact may be deemed to be forward-looking statements. Forward-looking statements are based on management's current

expectations and beliefs and involve risks, uncertainties and other factors that may cause actual events or results to differ materially

from those projected, including, without limitation, fluctuations in Esperion's stock price, changes in market conditions, and satisfaction

of customary closing conditions related to the proposed offering. These and other risks and uncertainties are described in greater detail

in Esperion's filings with the SEC, including in its Annual Report on Form 10-K for the year ended December 31, 2024 and

in its subsequent filings with the SEC. Any forward-looking statements contained in this press release speak only as of the date hereof,

and Esperion disclaims any obligation or undertaking to update or revise any forward-looking statements contained in this press release,

other than to the extent required by law. No representations or warranties (expressed or implied) are made about the accuracy of any such

forward-looking statements.

Esperion Contact Information: