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FORM 51-102F3 MATERIAL CHANGE REPORT Item 1: Name and Address of Company Eupraxia Pharmaceuticals Inc. (the Company ) 201-2067 Cadboro Bay Rd. Victoria, British Columbia Canada, V8R 5G4 Item 2: Date of Material Change

Key Takeaway: Eupraxia Pharmaceuticals Inc. announced the successful closure of its overnight marketed public offering of common shares. The company issued 8,260,435 shares at a price of C$4.10 each, resulting in gross proceeds of approximately C$33.9 million. The proceeds from the offering will be allocated to fund research and development, general administrative expenses, and working capital needs. The offering was conducted under a final prospectus supplement and was available in most provinces of Canada, excluding Quebec.

Market Sentiment Analysis

POSITIVE FACTORS

  • Eupraxia Pharmaceuticals successfully closed a major public offering.
  • The offering generated gross proceeds of C$33,867,784.
  • The funds will primarily support research and development activities.

Full Press Release Details

MATERIAL CHANGE REPORT
Eupraxia Pharmaceuticals Inc. (the Company )
201-2067 Cadboro Bay Rd.
Victoria, British Columbia
A news release announcing the material change was issued on March 15, 2024 through Globe Newswire and a copy was subsequently filed on
On March 15, 2024, the Company announced that it had closed its previously announced overnight marketed public offering (the
Offering ) of common shares of the Company (the Shares ). Pursuant to the Offering, Eupraxia issued 8,260,435 Shares at a price of C$4.10 per Share for gross proceeds of C$33,867,784, which includes the issuance
of 943,435 Shares upon partial exercise of the over-allotment option.
On March 15, 2024, the Company announced that it had closed its previously announced Offering of Shares. Pursuant to the Offering,
Eupraxia issued 8,260,435 Shares at a price of C$4.10 per Share for gross proceeds of C$33,867,784, which includes the issuance of 943,435 Shares upon partial exercise of the over-allotment option.
Eupraxia expects to use the net proceeds of the Offering, together with its existing cash and cash equivalents, primarily to fund research and
development activities, general and administrative expenses, a milestone payment, working capital needs and other general corporate purposes.
The Shares were offered pursuant to a final prospectus supplement dated March 12, 2024 to the Company s short form base shelf
prospectus dated February 5, 2024. The Shares were offered in each of the provinces of Canada, except Qu bec.
Ltd. acted as sole underwriter and bookrunner for the Offering.
No securities regulatory authority has either approved or disapproved the
contents of this material change report. This material change report shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of the common shares in the United States or in any province, state or
jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such province, state or jurisdiction. The securities have not been registered under the
United States Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from the registration requirements thereunder.
The Company does not intend to register any part of the Offering in the United States, and any public offering of securities to be made in the United States will only be made by means of a prospectus that may be obtained from the issuer and that
will contain detailed information about the Company and management, as well as financial statements.
For further information, please contact Bruce Cousins, President and Chief Financial Officer of the Company at

Frequently Asked Questions

What was announced by Eupraxia Pharmaceuticals on March 15, 2024?

Eupraxia Pharmaceuticals announced the closure of its public offering of shares.

How many shares did Eupraxia issue in the Offering?

Eupraxia issued 8,260,435 shares at a price of C$4.10 each.

What will Eupraxia use the proceeds from the Offering for?

Proceeds will fund research, administrative expenses, milestone payments, and working capital.

Who acted as the underwriter for Eupraxia's Offering?

Ltd. served as the sole underwriter and bookrunner for the Offering.

Were the shares registered in the United States?

No, the shares have not been registered under U.S. securities laws.

Last updated: Mar 15, 2024