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Enanta Pharmaceuticals to Present Preclinical Data for EDP-978, its KIT Inhibitor in Development for the Treatment of Type 2 Immune Diseases, at the 2026 AAAAI Annual Meeting

Key Takeaway: Enanta Pharmaceuticals announced that it will present preclinical data for EDP-978, a KIT inhibitor aimed at treating mast cell-mediated Type 2 immune diseases, at the 2026 AAAAI Annual Meeting. The presentations will take place on February 27, 2026, in Philadelphia, PA. Two posters will detail the drug's potency and pharmacokinetic profile.
Price reaction · baseline $13.83 (2026-02-09 close) · hit pre-market · clean, no other ENTA news in the window
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Market Sentiment Analysis

POSITIVE FACTORS

  • Presentation of promising preclinical data for EDP-978.
  • Potential for EDP-978 to treat Type 2 immune diseases.
  • Strong pharmacokinetic profile with once-daily dosing potential.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~63 mo
Minimal dilution risk
Lead asset
EDP-235
Phase 2 · COVID-19

Full Press Release Details

WATERTOWN, Mass.--(BUSINESS WIRE)--Enanta Pharmaceuticals, Inc.(NASDAQ:ENTA), a clinical-stage biotechnology company dedicated to creating small molecule drugs for viral infections and immunological diseases today announced that preclinical data for EDP-978, the Company’s KIT inhibitor in development for the treatment of mast cell-mediated, Type 2 immune diseases, will be presented in two poster presentations at the 2026 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting being held February 27 – March 2, 2026 in Philadelphia, PA.
Details of the presentations are as follows:
Abstract Title:Discovery of a Potent and Selective KIT inhibitor for Treatment of Mast Cell-Mediated DiseasesDate:Friday, February 27, 2026Time:2:45 – 3:45 PM ESTPoster Number:104Session:Allergic Skin DiseasesLocation:Convention Center, Level 2, Hall EPresenter:Tessa Cressey, Ph.D.
Abstract Title:EDP-978, a Potent KIT Inhibitor, Demonstrated Dose-Dependent Target-Engagement and a Favorable Pharmacokinetic Profile with Once-Daily Dosing Potential in HumansDate:Friday, February 27, 2026Time:2:45 – 3:45 PM ESTPoster Number:038Session:Allergic Skin DiseasesLocation:Convention Center, Level 2, Hall EPresenter:Yang Li, Ph.D.
Abstracts are available in an online supplement toThe Journal of Allergy and Clinical Immunology (JACI)platformhere. Further information about AAAAI 2026 can be foundhere. Posters will be available on Enanta’s websitehereafter presentations are held on February 27, 2026.

About Enanta Pharmaceuticals, Inc.

Enanta is using its robust, chemistry-driven approach and drug discovery capabilities to become a leader in the discovery and development of small molecule drugs for viral infections and immunological diseases. Enanta’s clinical programs are currently focused on respiratory syncytial virus (RSV) and its earlier-stage immunology pipeline aims to develop treatments for inflammatory diseases by targeting key drivers of the type 2 immune response, with KIT, STAT6 and MRGPRX2 inhibition.
Glecaprevir, a protease inhibitor discovered by Enanta, is part of one of the leading treatment regimens for curing hepatitis C virus (HCV) infection and is sold by AbbVie in numerous countries under the tradenames MAVYRET®(U.S.) and MAVIRET®(ex-U.S.) (glecaprevir/pibrentasvir). A portion of Enanta’s royalties from HCV products developed under its collaboration with AbbVie contribute ongoing funding to Enanta’s operations. Please visitwww.enanta.comfor more information.

Frequently Asked Questions

What is EDP-978?

EDP-978 is a KIT inhibitor developed by Enanta Pharmaceuticals for treating Type 2 immune diseases.

When will the EDP-978 data be presented?

The preclinical data for EDP-978 will be presented on February 27, 2026.

Where is the AAAAI Annual Meeting held?

The AAAAI Annual Meeting will take place in Philadelphia, PA.

What is the focus of Enanta Pharmaceuticals?

Enanta focuses on developing small molecule drugs for viral infections and immunological diseases.

Last updated: Feb 10, 2026