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Eledon Pharmaceuticals to Present Results from Phase 2 BESTOW Trial of Tegoprubart for the Prevention of Rejection in Kidney Transplantation at the American Society of Nephrology Kidney Week 2025 Annual Meeting

Key Takeaway: Eledon Pharmaceuticals announced an upcoming oral presentation at the American Society of Nephrology's Kidney Week 2025 Annual Meeting in Houston, TX. The presentation will focus on topline results from the Phase 2 BESTOW trial, which evaluates the efficacy and safety of tegoprubart for preventing rejection in kidney transplantation. Dr. Andrew Adams will lead the presentation on November 6, 2025, followed by a conference call on November 7 to discuss the results in greater detail. Eledon aims to advance its investigational product tegoprubart in the transplantation field.
Price reaction · baseline $2.85 (2025-10-16 close) · hit after-hours · clean, no other ELDN news in the window
day 0 close
+20.7%
day 1 · peak
+22.8%
day 3
+16.8%

Market Sentiment Analysis

POSITIVE FACTORS

  • Eledon Pharmaceuticals will present important topline results from Phase 2 BESTOW trial.
  • Tegoprubart shows potential for preventing rejection in kidney transplantation.
  • The upcoming presentation at a reputable conference indicates strong interest and validation in their research.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+90%
120-day peak, hindsight
Typical move
6.5%
average across 7 past catalysts
Cash runway
~11 mo
Medium dilution risk
Lead asset
AT-1501
Phase 2 · Kidney Transplant Rejection

Full Press Release Details

IRVINE, Calif., Oct. 17, 2025 (GLOBE NEWSWIRE) -- Eledon Pharmaceuticals, Inc. (“Eledon”) (Nasdaq: ELDN) today announced an oral presentation will be featured at the American Society of Nephrology’s upcoming Kidney Week 2025 Annual Meeting taking place in Houston, TX, from November 5-8, 2025. The oral presentation will highlight topline results from the Phase 2 BESTOW trial evaluating tegoprubart for the prevention of rejection in kidney transplantation.
Details of the oral presentation are below:
Title:  Efficacy and Safety of Tegoprubart for the Prevention of Rejection in Kidney Transplantation: Results from the Phase 2 BESTOW Trial
Presenter:  Andrew Adams, M.D., Ph.D., Professor of Surgery and Chief Division of Transplantation, John S. Najarian Surgical Chair in Clinical Transplantation, Department of Surgery, University of Minnesota; Executive Medical Director, Solid Organ Transplant Service Line, M Health Fairview
Abstract Publication Number: TH-OR089
Session Title:  Late-Breaking Research Orals - 1
Session Date and Time: November 6, 2025, from 4:30 p.m. to 6:00 p.m. CT
Session Room: Grand Ballroom C (Convention Center)
Presentation Time: 5:30 p.m. to 5:42 p.m. CT
Eledon will hold a conference call on November 7, 2025 at 8:00 a.m. Eastern Time to discuss the Phase 2 BESTOW trial results presented at Kidney Week. The dial-in numbers are 1-800-717-1738 for domestic callers and 1-646-307-1865 for international callers. The conference ID is 92427. A live webcast of the conference call will be available on the Investor Relations section of the Company's website at www.eledon.com. The webcast will be archived on the website following the completion of the call.
About Eledon Pharmaceuticals and tegoprubart
Eledon Pharmaceuticals, Inc. is a clinical stage biotechnology company that is developing immune-modulating therapies for the management and treatment of life-threatening conditions. The Company’s lead investigational product is tegoprubart, an anti-CD40L antibody with high affinity for the CD40 Ligand, a well-validated biological target that has broad therapeutic potential. The central role of CD40L signaling in both adaptive and innate immune cell activation and function positions it as an attractive target for non-lymphocyte depleting, immunomodulatory therapeutic intervention. The Company is building upon a deep historical knowledge of anti-CD40 Ligand biology to conduct preclinical and clinical studies in kidney allograft transplantation, xenotransplantation, and amyotrophic lateral sclerosis (ALS). Eledon is headquartered in Irvine, California. For more information, please visit the Company’s website at www.eledon.com.
Follow Eledon Pharmaceuticals on social media: LinkedIn; Twitter
Source: Eledon Pharmaceuticals

Frequently Asked Questions

When is Eledon's presentation at Kidney Week 2025?

Eledon's presentation is on November 6, 2025, from 4:30 p.m. to 6:00 p.m. CT.

What will the presentation focus on?

The presentation will highlight topline results from the Phase 2 BESTOW trial.

Who is presenting at the conference?

Andrew Adams, M.D., Ph.D., will present the trial results.

How can I join the conference call?

Join the call on November 7, 2025, at 8:00 a.m. ET using dial-in numbers.

What is tegoprubart?

Tegoprubart is an anti-CD40L antibody targeting immune modulation in therapy.

Last updated: Oct 17, 2025