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Eledon Pharmaceuticals to Present New Long-Term Data from Phase 2 BESTOW Trial of Tegoprubart for the Prevention of Rejection in Kidney Transplantation at American Transplant Congress

Key Takeaway: Eledon Pharmaceuticals announced that it will present new long-term clinical data from its tegoprubart program at the upcoming American Transplant Congress from June 20-24, 2026. This will include updated findings from the Phase 2 BESTOW trial and an extension study focused on preventing kidney transplant rejection. The presentations will feature expert input from Andrew Adams, M.D., Ph.D., highlighting the significance of tegoprubart in transplantation therapies. Following the presentations, a conference call will provide further insights into the data shared at the Congress.
Price reaction · baseline $3.58 (2026-05-19 close) · hit after-hours · clean, no other ELDN news in the window
day 0 close
+7.3%
day 1 · peak
+8.7%
day 3
+8.7%

Market Sentiment Analysis

POSITIVE FACTORS

  • Eledon Pharmaceuticals will present new clinical data from the Phase 2 BESTOW trial.
  • The presentation will feature long-term data on tegoprubart, indicating ongoing progress in organ transplantation therapy.
  • The involvement of a reputable presenter adds credibility to the findings.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+90%
120-day peak, hindsight
Typical move
6.5%
average across 7 past catalysts
Cash runway
~11 mo
Medium dilution risk
Lead asset
AT-1501
Phase 2 · Kidney Transplant Rejection

Full Press Release Details

IRVINE, Calif., May 20, 2026 (GLOBE NEWSWIRE) -- Eledon Pharmaceuticals, Inc. (“Eledon”) (Nasdaq: ELDN) today announced that the Company will present new clinical data from its tegoprubart program in patients undergoing kidney transplantation in an oral and a poster presentation at the American Transplant Congress (ATC) taking place in Boston, MA from June 20-24, 2026. Results will include updated data from the Phase 2 BESTOW clinical trial and new long-term data from the Phase 2 BESTOW extension study.
Details on the presentations are below:
Title: Phase 2 BESTOW Trial: Evaluating Tegoprubart’s Safety and Efficacy in Preventing Kidney Transplant Rejection
Presenter: Andrew Adams, M.D., Ph.D., Professor of Surgery and Chief Division of Transplantation, John S. Najarian Surgical Chair in Clinical Transplantation, Department of Surgery, University of Minnesota; Executive Medical Director, Solid Organ Transplant Service Line, M Health Fairview
Abstract Publication Number: 585
Session Title: Emerging Discoveries Oral Abstract Session - Kidney: Biomarkers -3
Session Date and Time: Monday, June 22, 2026, from 11:15 a.m. - 12:15 p.m. ET
Session Room: 253BC (Level 2)
Presentation Time: 12:03 p.m. – 12:15 p.m. ET
Title: Phase 2 BESTOW Extension Trial Evaluating Tegoprubart’s Long-Term Safety and Efficacy in Preventing Kidney Transplant Rejection
Session Date and Time: Saturday, June 20, 2026, from 5:45 p.m. - 6:45 p.m. ET
Following the conference, a copy of the oral and poster presentation will be available in the Investors section of the Company’s website at https://ir.eledon.com/news-and-events/publications-and-presentations.
Eledon will hold a conference call on June 22, 2026 at 8:00 a.m. Eastern Time to discuss updated data from the Phase 2 BESTOW clinical trial and new long-term data from the Phase 2 BESTOW extension study presented at the American Transplant Congress. The dial-in numbers are 1-800-717-1738 for domestic callers and 1-646-307-1865 for international callers. The conference ID is 84665. A live webcast of the conference call will be available on the Investor Relations section of the Company's website at www.eledon.com. The webcast will be archived on the website following the completion of the call.
About Eledon Pharmaceuticals and tegoprubart
Eledon Pharmaceuticals, Inc. is a clinical stage biotechnology company that is developing immune-modulating therapies for the management and treatment of life-threatening conditions. The Company’s lead investigational product is tegoprubart, an anti-CD40L antibody with high affinity for the CD40 Ligand, a well-validated biological target that has broad therapeutic potential. The central role of CD40L signaling in both adaptive and innate immune cell activation and function positions it as an attractive target for non-lymphocyte depleting, immunomodulatory therapeutic intervention. The Company is building upon a deep historical knowledge of anti-CD40 Ligand biology to conduct preclinical and clinical studies in kidney allograft transplantation, xenotransplantation, islet cell transplantation, liver transplantation and amyotrophic lateral sclerosis (ALS). Eledon is headquartered in Irvine, California. For more information, please visit the Company’s website at www.eledon.com.
Follow Eledon Pharmaceuticals on social media: LinkedIn; X
Source: Eledon Pharmaceuticals

Frequently Asked Questions

What is the focus of Eledon's upcoming presentations?

Eledon will present new clinical data on tegoprubart for preventing kidney transplant rejection.

When will Eledon present at the American Transplant Congress?

Presentations will occur from June 20-24, 2026, in Boston, MA.

Who is presenting Eledon's clinical trial findings?

Dr. Andrew Adams will present data on tegoprubart's safety and efficacy.

How can I access Eledon's presentation after the congress?

The presentations will be available in the Investors section of Eledon's website.

What is tegoprubart's role in Eledon's research?

Tegoprubart is an anti-CD40L antibody aimed at preventing transplant rejection.

Last updated: May 20, 2026