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Eledon Announces Presentation of Updated Data from Investigator-Initiated Islet Transplant Trial of Tegoprubart in Patients with Type 1 Diabetes at American Diabetes Association (ADA) 2026 Scientific Sessions

Key Takeaway: Eledon Pharmaceuticals announced that updated results from an investigator-initiated trial of tegoprubart will be presented at the 2026 American Diabetes Association Scientific Sessions. The presentation, led by Dr. Piotr Witkowski, will focus on the use of anti-CD40L to enhance graft survival in islet allotransplantation. This highlights Eledon's efforts in developing immune-modulating therapies for type 1 diabetes. The conference takes place from June 5-9 in New Orleans, Louisiana.

Market Sentiment Analysis

POSITIVE FACTORS

  • Eledon is presenting updated trial data at a significant conference.
  • The lead product tegoprubart shows promise for islet cell transplantation.
  • The study is being conducted by a reputable institution (University of Chicago).

Full Press Release Details

IRVINE, Calif., June 04, 2026 (GLOBE NEWSWIRE) -- Eledon Pharmaceuticals, Inc. (“Eledon”) (Nasdaq: ELDN) today announced that updated results from an investigator-initiated trial being conducted at the University of Chicago Medicine Transplant Institute will be presented by Piotr Witkowski, M.D., Ph.D., Director of the Pancreas and Islet Transplant Program at UChicago Medicine, at the American Diabetes Association 86th Scientific Sessions, taking place June 5-9, 2026, in New Orleans, Louisiana.
Details of the oral presentation are as follows:
Presentation Title: Anti-CD40L to Induce Graft Survival and Function in Islet Allotransplantation
Session: Immune Modulatory Strategies for Next-Generation Cell Therapies
Date: Sunday, June 7, 2026
Time: 2:30 p.m. – 3:00 p.m. CT
About Eledon Pharmaceuticals and tegoprubart
Eledon Pharmaceuticals, Inc. is a clinical stage biotechnology company that is developing immune-modulating therapies for the management and treatment of life-threatening conditions. The Company’s lead investigational product is tegoprubart, an anti-CD40L antibody with high affinity for the CD40 Ligand, a well-validated biological target that has broad therapeutic potential. The central role of CD40L signaling in both adaptive and innate immune cell activation and function positions it as an attractive target for non-lymphocyte depleting, immunomodulatory therapeutic intervention. The Company is building upon a deep historical knowledge of anti-CD40 Ligand biology to conduct preclinical and clinical studies in kidney allograft transplantation, xenotransplantation, islet cell transplantation, liver transplantation and amyotrophic lateral sclerosis (ALS). Eledon is headquartered in Irvine, California. For more information, please visit the Company’s website at www.eledon.com.
Follow Eledon Pharmaceuticals on social media: LinkedIn; Twitter
Source: Eledon Pharmaceuticals

Tags

Islet cell transplant

Frequently Asked Questions

What is the focus of Eledon's clinical trials?

Eledon's trials focus on immune-modulating therapies for critical conditions.

Who is presenting at the American Diabetes Association sessions?

Dr. Piotr Witkowski will present updated trial results at the event.

When is Eledon's presentation scheduled?

The presentation is on June 7, 2026, at 2:30 p.m. CT.

What is tegoprubart?

Tegoprubart is an anti-CD40L antibody being developed by Eledon Pharmaceuticals.

Where is Eledon Pharmaceuticals located?

Eledon Pharmaceuticals is based in Irvine, California.

Last updated: Jun 4, 2026