Full Press Release Details
NorthStrive Biosciences Signs Definitive License Agreement for
Commercialization of EL-22 and EL-32, a Myostatin-Engineered Probiotic for Muscle Preservation in Animal Health
NEWPORT BEACH, Calif., Feb. 11, 2026 (GLOBE NEWSWIRE) -- Northstrive
Biosciences Inc. ("Northstrive"), a wholly owned subsidiary of PMGC Holdings Inc. (NASDAQ: ELAB) (the "Company,"
"PMGC," "we," or "our"), today announced that it has executed a definitive, exclusive license agreement
("License Agreement") with Modulant Biosciences LLC ("Modulant"), following the previously announced binding term
sheet dated May 12, 2025.
The License Agreement covers NorthStrive's EL-22 and EL-32 assets
and, pursuant to its terms, grants Modulant an exclusive, royalty-bearing, sublicensable license to develop, manufacture, and commercialize
products derived from these technologies solely for non-human animal health applications, including use as a feed additive. This license
("License") applies on a worldwide basis, excluding the Republic of Korea. Modulant agreed to pay value to Northstrive in
exchange for the License granted under the License Agreement.
EL-22 and EL-32 are based on proprietary intellectual property targeting
myostatin and activin-A pathways, which are key biological regulators of muscle development, strength, and metabolic efficiency. These
pathways are increasingly viewed as important targets across a range of animal health and nutrition applications, including livestock
productivity, feed efficiency, and companion animal muscle health and aging.
The License Agreement encompasses issued patents, pending patent applications,
and associated proprietary know-how underlying the EL-22 and EL-32 programs. Under the terms of the License Agreement, Modulant is responsible
for all development, manufacturing, regulatory, and commercialization activities for licensed products within the animal health field,
using commercially reasonable efforts. The License Agreement expressly excludes any human pharmaceutical or clinical applications.
The License Agreement also provides for:
The collaboration represented by this License Agreement between Northstrive
and Modulant is intended to advance EL-22- and EL-32-derived products toward commercialization in the global animal health market,
which continues to grow alongside rising demand for improved animal performance, wellness, and longevity.
The execution of the License Agreement represents a key milestone for
NorthStrive, converting the previously announced term sheet into a fully executed definitive agreement that enables focused development
and commercialization activities for EL-22 and EL-32 within the animal health sector.
While the definitive licensing agreement provides a framework for the
development and commercialization of EL-22 and EL-32 for animal health applications, there can be no assurance that Modulant will be successful
in developing, obtaining any required regulatory approvals for, or commercializing products derived from these technologies, or that any
such products will achieve market acceptance.
About Northstrive Biosciences Inc.
Northstrive Biosciences Inc., a PMGC Holdings Inc. company, is a biopharmaceutical
company focusing on the development and acquisition of cutting-edge aesthetic medicines. Northstrive's lead asset, EL-22, leverages
an engineered probiotic approach to address obesity's pressing issue of preserving muscle while on weight loss treatments, including
GLP-1 receptor agonists. For more information, please visit www.northstrivebio.com.
About PMGC Holdings Inc.
PMGC Holdings Inc. is a diversified holding company that manages and
grows its portfolio through strategic acquisitions, investments, and development across various industries. We are committed to exploring
opportunities in multiple sectors to maximize growth and value. For more information, please visit https://www.pmgcholdings.com.
About Modulant Biosciences LLC
Modulant Biosciences is a biotechnology company specializing in veterinary
medicine innovation. Led by Dr. Tom Campi, Modulant is focused on developing novel drugs and biologics for livestock, companion, and aquatic
animals. Currently, Modulant's synergistic pipeline includes first in class antivirals for livestock and companion animals and a
"One Drug for All Cancers" platform.
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not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of
1995, as amended. Words such as "believes," "expects," "plans," "potential," "would"
and "future" or similar expressions such as "look forward" are intended to identify forward-looking statements.
Forward-looking statements are made as of the date of this press release and are neither historical facts nor assurances of future performance.
Instead, they are based only on our current beliefs, expectations and assumptions regarding the future of our business, future plans and
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conditions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in
circumstances that are difficult to predict and many of which are outside of our control. Although the Company believes that the expectations
expressed in these forward-looking statements are reasonable, it cannot assure you that such expectations will turn out to be correct,
and the Company cautions investors that actual results may differ materially from the anticipated results. Therefore, you should not rely
on any of these forward-looking statements. These and other risks are described more fully in PMGC's filings with the United States
Securities and Exchange Commission ("SEC"), including the "Risk Factors" section of the Company's Annual
Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on March 28, 2025, and its other documents subsequently filed
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