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Precision BioSciences Receives Approval in Hong Kong to Expand PBGENE-HBV Phase 1 ELIMINATE-B Trial for the Treatment of Chronic Hepatitis B

Key Takeaway: Precision BioSciences has received approval in Hong Kong to expand its PBGENE-HBV Phase 1 ELIMINATE-B trial, marking a significant milestone as it is the first in vivo gene editing clinical trial for chronic hepatitis B in the region. This approval is the second clinical trial application for PBGENE-HBV in 2024, and the study is currently recruiting patients globally.
Price reaction · baseline $4.45 (2024-12-18T18:00:00.000Z) · hit during market hours · clean, no other DTIL news in the window
day 0 close · peak
-7.2%
day 1
+3.4%
day 3
+1.1%

Market Sentiment Analysis

POSITIVE FACTORS

  • First clinical trial application clearance for in vivo gene editing in Hong Kong.
  • Second CTA approval for PBGENE-HBV in 2024.
  • Global, multi-site study actively recruiting patients.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+24%
120-day peak, hindsight
Typical move
4.8%
average across 2 past catalysts
Cash runway
~19 mo
Low dilution risk
Lead asset
Targeted CEA CAR-T
Phase 1 · Advanced Lung Cancer

Full Press Release Details

– Approval in Hong Kong marks the first clinical trial application clearance of an in vivo gene editing approach for chronic hepatitis B in Hong Kong and the second CTA approval for PBGENE-HBV in 2024 – ELIMINATE-B is a global, multi-site study now actively recruiting patients; expected to report

Frequently Asked Questions

What is the PBGENE-HBV trial?

The PBGENE-HBV trial is a Phase 1 clinical study for treating chronic hepatitis B using gene editing.

Where has the PBGENE-HBV trial been approved?

The trial has received approval in Hong Kong, marking a significant milestone.

What does the ELIMINATE-B study focus on?

The ELIMINATE-B study focuses on the treatment of chronic hepatitis B through gene editing.

Is the trial actively recruiting patients?

Yes, the ELIMINATE-B trial is currently actively recruiting patients globally.

Last updated: Dec 18, 2024