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Precision BioSciences Announces U.S. Patent Covering PBGENE-HBV for Chronic Hepatitis B and Updates Program Status

Key Takeaway: Precision BioSciences has announced the granting of a U.S. patent for its PBGENE-HBV program, which targets chronic Hepatitis B and is protected until 2042. The Phase 1 ELIMINATE-B trial is currently progressing, with dosing for Cohort 3 set to begin in the third quarter of 2025. This development enhances the company's intellectual property and clinical advancement.
Price reaction · baseline $5.07 (2025-09-05 close) · hit pre-market · clean, no other DTIL news in the window
day 0 close · peak
-2%

Market Sentiment Analysis

POSITIVE FACTORS

  • U.S. patent protection strengthens intellectual property portfolio.
  • PBGENE-HBV program shows progress with ongoing clinical trials.
  • Cohort 3 dosing initiated, indicating advancement in the trial.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+24%
120-day peak, hindsight
Typical move
4.8%
average across 2 past catalysts
Cash runway
~19 mo
Low dilution risk
Lead asset
Targeted CEA CAR-T
Phase 1 · Advanced Lung Cancer

Full Press Release Details

– Strengthens the Company’s intellectual property portfolio for lead in vivo program PBGENE-HBV with U.S. patent protection into 2042- – Phase 1 ELIMINATE-B trial progressing through clinical investigation with dosing of Cohort 3 initiated in Third Quarter of 2025- DURHAM, N.C.

Frequently Asked Questions

What is PBGENE-HBV?

PBGENE-HBV is Precision BioSciences' lead program targeting chronic Hepatitis B.

How long is the patent protection for PBGENE-HBV?

The U.S. patent for PBGENE-HBV is protected until 2042.

What is the status of the ELIMINATE-B trial?

The Phase 1 ELIMINATE-B trial is progressing, with Cohort 3 dosing starting in Q3 2025.

Where is Precision BioSciences located?

Precision BioSciences is based in Durham, North Carolina.

Last updated: Sep 8, 2025