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Daré Bioscience’s Sildenafil Cream Data in Postmenopausal Women Published in Menopause - The Journal of The Menopause Society

Key Takeaway: Daré Bioscience's clinical study on its 3.6% topical sildenafil cream showed positive results, demonstrating good tolerance among postmenopausal women with minimal systemic exposure. The company is actively working to advance this formulation through the FDA's 505(b)(2) regulatory pathway, indicating progress in its development.

Market Sentiment Analysis

POSITIVE FACTORS

  • Topical sildenafil cream was well tolerated in the study.
  • Minimal systemic exposure was observed across all doses.
  • The company is advancing toward FDA's 505(b)(2) pathway.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Cash runway
~5 mo
High dilution risk
Lead asset
Lopinavir/ ritonavir
Phase 2 · Human Papilloma Virus (HPV)

Full Press Release Details

Daré’s proprietary formulation of topical sildenafil cream, 3.6% was well tolerated across all evaluated doses in the clinical study, with minimal systemic exposure Company continues activities necessary to advance its Sildenafil Cream toward the FDA’s 505(b)(2) regulatory pathway* while in

Frequently Asked Questions

What is the formulation of Daré's sildenafil cream?

Daré's sildenafil cream is a proprietary formulation with a concentration of 3.6%.

How was the sildenafil cream tolerated in the study?

The cream was well tolerated across all evaluated doses with minimal systemic exposure.

What regulatory pathway is Daré pursuing for the cream?

Daré is advancing its sildenafil cream through the FDA's 505(b)(2) regulatory pathway.

Who participated in the clinical study?

The clinical study involved postmenopausal women.

Last updated: Aug 26, 2026