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Cytokinetics to Announce Topline Results from ACACIA-HCM, the Pivotal Phase 3 Clinical Trial of Aficamten in Patients with Non-Obstructive Hypertrophic Cardiomyopathy, on May 5, 2026

Key Takeaway: Cytokinetics, Inc. is set to announce topline results from the pivotal Phase 3 ACACIA-HCM clinical trial, evaluating Aficamten in patients with non-obstructive hypertrophic cardiomyopathy, on May 5, 2026. A conference call will follow at 8:00 AM Eastern Time to discuss the outcome. The company is recognized for its focus on advancing therapies for cardiac muscle dysfunction, with additional treatments in development for related conditions. This announcement marks a key milestone for the company as they continue to innovate in cardiovascular medicine.

Market Sentiment Analysis

POSITIVE FACTORS

  • Cytokinetics will announce topline results from a pivotal Phase 3 trial.
  • The company's innovative therapies target significant cardiac conditions.
  • Cytokinetics has a strong foundation in muscle biology with over 25 years of experience.

Full Press Release Details

Company to Host Conference Call and Webcast Tuesday May 5 at 8:00 AM Eastern Time
SOUTH SAN FRANCISCO, Calif., May 04, 2026 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced it will report topline results from ACACIA-HCM (Assessment Comparing Aficamten to Placebo on Cardiac Endpoints In Adults with Non-Obstructive HCM) on Tuesday, May 5, 2026. Following the announcement, Cytokinetics will host a conference call at 8:00 AM Eastern Time to discuss the results.
The conference call will be simultaneously webcast and can be accessed from the Investors & Media section of Cytokinetics’ website at https://ir.cytokinetics.com or the following link: ACACIA-HCM Topline Results. An archived replay of the webcast will be available via Cytokinetics’ website for six months.
Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. Cytokinetics’ MYQORZO® (aficamten) is a cardiac myosin inhibitor approved in the U.S., Europe and China for the treatment of adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM). Cytokinetics is also developing omecamtiv mecarbil, an investigational cardiac myosin activator for the potential treatment of patients with heart failure with severely reduced ejection fraction and ulacamten, an investigational cardiac myosin inhibitor for the potential treatment of heart failure with preserved ejection fraction, while continuing pre-clinical research and development in muscle biology.
Omecamtiv mecarbil and ulacamten are investigational medicines. They have not been approved nor determined to be safe or efficacious for any disease state or any indication by FDA or any other regulatory agency.
Forward-Looking Statements
This press release contains forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the “Act”). Cytokinetics disclaims any intent or obligation to update these forward-looking statements and claims the protection of the Act’s Safe Harbor for forward-looking statements. Examples of such statements include, but are not limited to, statements relating to Cytokinetics’ and its partners’ research and development activities of Cytokinetics’ product candidates. Such statements are based on management’s current expectations, but actual results may differ materially due to various risks and uncertainties, including, but not limited to the risks related to Cytokinetics’ business outlines in Cytokinetics’ filings with the Securities and Exchange Commission. Forward-looking statements are not guarantees of future performance, and Cytokinetics’ actual results of operations, financial condition and liquidity, and the development of the industry in which it operates, may differ materially from the forward-looking statements contained in this press release. Any forward-looking statements that Cytokinetics makes in this press release speak only as of the date of this press release. Cytokinetics assumes no obligation to update its forward-looking statements whether as a result of new information, future events or otherwise, after the date of this press release.
CYTOKINETICS® and the CYTOKINETICS C-shaped logo are registered trademarks of Cytokinetics in the U.S. and certain other countries.
MYQORZO® is a registered trademark of Cytokinetics in the U.S. and the European Union.
Senior Vice President, Corporate Affairs

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Frequently Asked Questions

When will Cytokinetics announce the ACACIA-HCM results?

Cytokinetics will announce the ACACIA-HCM results on May 5, 2026.

How can I access the conference call about ACACIA-HCM?

The conference call can be accessed through Cytokinetics’ Investors & Media webpage.

Is MYQORZO® approved for other conditions?

MYQORZO® is approved for symptomatic obstructive hypertrophic cardiomyopathy.

What are omecamtiv mecarbil and ulacamten?

Omecamtiv mecarbil and ulacamten are investigational medicines not yet approved.

What should I know about forward-looking statements?

Forward-looking statements are not guarantees and may differ due to uncertainties.

Last updated: May 4, 2026