CureVac Streamlines European Network for mRNA Product Manufacturing CureVac right-sizes manufacturing network to adapt to changes in vaccine peak demands Demand reassessed for first-generation COVID-19 vaccine candidate,

Streamlines European Network for mRNA Product Manufacturing

Germany/ BOSTON, USA - September 14, 2021 - CureVac N.V. (Nasdaq: CVAC), a global biopharmaceutical company developing

a new class of transformative medicines based on messenger ribonucleic acid ("mRNA"), today announced its strategic decision

to adjust the long-term footprint of the external European manufacturing network for its mRNA product pipeline. The decision was made

in response to the reduced short-term peak demand for vaccines following the first wave of the pandemic vaccination efforts and corresponding

changes in the demand of its first-generation COVID-19 vaccine candidate, CVnCoV, currently under regulatory review with the European

Medicines Agency (EMA). As a result, the existing contracts with WACKER for the manufacturing of the mRNA drug substance of CVnCoV and

Celonic for the manufacturing and formulation of the mRNA drug substance of CVnCoV will be terminated. CureVac's existing agreements

with Rentschler Biopharma and Novartis for mRNA production and formulation are unaffected by this adjustment and remain in place. Streamlining

of capacity does not limit availability of clinical trial material for CV2CoV, the second-generation COVID-19 vaccine candidate jointly

developed with GSK, expected to enter the clinic in the fourth quarter of 2021.

increase in mRNA manufacturing capacity together with the progress of large-scale vaccination efforts have strongly changed the demand

for our first-generation COVID-19 vaccine, CVnCoV, over the last months," said Dr. Malte Greune, Chief Operating Officer of CureVac.

"The development from a very high, short-term pandemic demand to broader availability of vaccines has led us to re-evaluate our

immediate manufacturing capacity requirements in order to align the capacity with actual commercial and clinical capacity needs for CVnCoV.

We would like to thank both our manufacturing partners for their dedication and effort in achieving our common goal to combat the pandemic

with this key technology."

CureVac first announced

the build-up of its broad external European manufacturing network in November 2020, next to the ongoing expansion of large in-house clinical

and commercial manufacturing capacities. Since then, several manufacturing agreements were made with highly experienced Contract Development

and Manufacturing Organization partners for each of the key manufacturing steps for CVnCoV. The agreements with WACKER and Celonic were

cancelled within the agreed contractual termination provisions. The parties agreed not to disclose financial details of the cancellation.

is a global biopharmaceutical company in the field of messenger RNA (mRNA) technology, with more than 20 years of expertise in developing

and optimizing the versatile biological molecule for medical purposes. The principle of CureVac's proprietary technology is the

use of optimized mRNA as a data carrier to instruct the human body to produce its own proteins capable of fighting a broad range of diseases.

In July 2020, CureVac entered in a collaboration with GSK to jointly develop new products in prophylactic vaccines for infectious diseases

based on CureVac's second-generation mRNA technology. In February 2021, this collaboration was extended to the development of second-generation

COVID-19 vaccine candidates. Based on its proprietary technology, CureVac has built a deep clinical pipeline across the areas of prophylactic

vaccines, cancer therapies, antibody therapies, and the treatment of rare diseases. CureVac had its initial public offering on the New

York Nasdaq in August 2020. It is headquartered in T bingen, Germany, and employs more than 700 people at its sites in T bingen,

Frankfurt, and Boston, USA. Further information can be found at www.curevac.com.

CureVac Investor Relations Contact

Dr. Sarah Fakih, Vice President Corporate

Communications and Investor Relations

CureVac, T bingen, Germany

T: +49 7071 9883-1298

M: +49 160 90 496949

CureVac Media Contact

Anna Kamilli, Manager Communications

CureVac, T bingen, Germany

T: +49 7071 9883-1684

Bettina J dicke-Braas, Manager

CureVac, T bingen, Germany

T: 49 7071 9883-1087

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objectives, assumptions or projections of CureVac N.V. and/or its wholly owned subsidiaries CureVac AG, CureVac Real Estate GmbH,

CureVac Inc., CureVac Swiss AG and CureVac Corporate Services GmbH (the "company") regarding future events or future

results, in contrast with statements that reflect historical facts. Examples include discussion of the potential efficacy of the

company's vaccine and treatment candidates and the company's strategies, financing plans, growth opportunities and

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"intend," "believe," "estimate," "plan," "seek," "project,"

or "expect," "may," "will," "would," "could," "potential,"

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based on management's current beliefs and assumptions and on information currently available to the company. However, these

forward-looking statements are not a guarantee of the company's performance, and you should not place undue reliance on such

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worldwide economic conditions and ongoing instability and volatility in the worldwide financial markets, ability to obtain funding,

ability to conduct current and future preclinical studies and clinical trials, the timing, expense and uncertainty of regulatory

approval, reliance on third parties and collaboration partners, ability to commercialize products, ability to manufacture any

products, possible changes in current and proposed legislation, regulations and governmental policies, pressures from increasing

competition and consolidation in the company's industry, the effects of the COVID-19 pandemic on the company's business

and results of operations, ability to manage growth, reliance on key personnel, reliance on intellectual property protection,

ability to provide for patient safety, and fluctuations of operating results due to the effect of exchange rates or other factors.

Such risks and uncertainties may cause the statements to be inaccurate and readers are cautioned not to place undue reliance on such

statements. Many of these risks are outside of the company's control and could cause its actual results to differ materially

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please reference the company's reports and documents filed with the U.S. Securities and Exchange Commission (SEC). You may get

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