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FORM 51-102F3 MATERIAL CHANGE REPORT Item 1 Name and Address of Company Aeterna Zentaris Inc. (the Company ) c/o Stikeman Elliott LLP 1155 Ren -L vesque Blvd. West 41st Floor Montr al, Qu bec H3B 3V2 Item 2 Date of Mater

Key Takeaway: MATERIAL CHANGE REPORT Item 1 Name and Address of Company Aeterna Zentaris Inc. (the Company ) c/o Stikeman Elliott LLP 1155 Ren -L vesque Blvd. West Item 2 Date of Material Change On December 8, 2017, the Company issued a news release indicating the material change, which

Full Press Release Details

MATERIAL CHANGE REPORT
Item 1 Name and Address of Company
Aeterna Zentaris Inc. (the Company )
c/o Stikeman Elliott LLP
1155 Ren -L vesque Blvd. West
Item 2 Date of Material Change
On December 8, 2017, the Company issued a news release indicating the material change, which was disseminated on the GlobeNewswire news service.
Item 4 Summary of Material Change
On December 8, 2017, the Company announced the departure of its Interim Chief Financial Officer, Jeffrey Whitnell, effective December 7, 2017. The Company is currently reviewing its resource requirements with respect to its finance department and has commenced a search for Mr. Whitnell s replacement as principal financial officer.
Item 5.1 Full Description of Material Change
On December 8, 2017, the Company announced the departure of its Interim Chief Financial Officer, Jeffrey Whitnell, effective December 7, 2017. The Company is currently reviewing its resource requirements with respect to its finance department and has commenced a search for Mr. Whitnell s replacement as principal financial officer.
Item 5.2 Disclosure for Restructuring Transactions
Item 6 Reliance on subsection 7.1(2) or (3) of National Instrument 51-102
Item 7 Omitted Information
Item 8 Executive Officer
Further information regarding the matter described in this report may be obtained from Michael V. Ward, Chief Executive Officer, at 843-900-3223 or IR@AEZSinc.com.
Item 9 Date of Report
Last updated: Dec 7, 2017