Cosmos Health CEO Issues Letter to Shareholders: Building a Global Healthcare Powerhouse with $300M Digital Financing Facility, U.S. Manufacturing Expansion, and AI Innovation CHICAGO, IL / GLOBE NEWSWIRE /

cosm_ex991.htm EXHIBIT 99.1

Cosmos Health CEO Issues Letter to Shareholders: Building a Global Healthcare Powerhouse with $300M Digital Financing Facility, U.S. Manufacturing Expansion, and AI Innovation

CHICAGO, IL / GLOBE NEWSWIRE / September 29, 2025 / Cosmos Health Inc. ("Cosmos Health" or the "Company") (NASDAQ:COSM), a diversified, vertically integrated global healthcare group, today announced that its Chief Executive Officer, Greg Siokas, has issued the following letter to the Company's shareholders.

Dear Fellow Shareholders,

Cosmos Health stands at a defining moment in its journey. Over the past year, we have made decisive progress - refining our strategy, reinforcing our operations, and positioning every business unit to contribute to a common vision of sustainable growth and long-term value creation.

From our expanding manufacturing footprint in the United States to the global reach of our Sky Premium Life brand, the strengthening of our wholesale operations, the signing of long-term contract manufacturing agreements, and the breakthroughs emerging from our R&D pipeline, every part of our organization has made meaningful progress. At the same time, the launch of our digital treasury strategy underscores our commitment to innovation and resilience in an evolving global landscape.

These achievements mark the beginning of a new era for Cosmos Health - one defined by growth, innovation, and resilience. With the continued trust and support of our shareholders, we are building a company not only prepared for the challenges ahead, but also poised to lead in the years to come.

I. Vision & Ambition

Cosmos Health is at a turning point in its journey. We have aligned every business unit around a common goal: creating a global healthcare and life sciences platform that integrates pharmaceuticals, nutraceuticals, manufacturing, logistics, research and innovation, and digital finance under one roof.

Our purpose is clear: to make high-quality healthcare accessible worldwide while driving innovation at the intersection of science, technology, and digital finance. This is not simply about growth for its own sake, but about building a company defined by resilience, creativity, and the capacity to lead in rapidly evolving industries.

A Bold Ambition for the Future

Looking ahead to 2030, our ambition is to transform Cosmos Health into a global powerhouse. We will achieve this by scaling our branded products, deepening our scientific pipeline, and harnessing AI and blockchain to reshape both the discovery and delivery of healthcare.

Our long-term direction includes, among other priorities:

Expanding our global reach across Europe, North America, the Middle East, and Asia.

Scaling branded nutraceuticals and pharmaceuticals into globally recognized products.

Building a proprietary therapeutics pipeline with multi-billion-dollar market potential.

Leveraging AI and blockchain to redefine drug discovery, intellectual property monetization, and corporate treasury management.

Delivering sustained shareholder returns through financial innovation, operational excellence, and long-term growth.

At every step, we balance near-term profitability with long-term investment, ensuring that Cosmos Health remains both innovative and sustainable.

Foundations of Strength

Our strategy is rooted in three core strengths that give Cosmos Health a significant advantage:

Diversification: By operating across multiple healthcare segments, from R&D and pharmaceuticals to consumer brands and logistics, we reduce reliance on any single revenue stream.

Vertical Integration: Ownership of manufacturing, distribution, and branded products gives us control over quality, cost, and scalability.

Innovation-Driven Growth: From AI-enabled platforms like Cloudscreen to blockchain-enhanced treasury and supply chain systems, we are embedding innovation into every part of the business.

Building for the Long Term

These foundations allow us to pursue ambitious goals while maintaining resilience. With such foundations in place, we believe Cosmos Health is positioned not only to capture emerging market opportunities but also to help shape the future of global healthcare delivery. Just as importantly, we see them as ensuring that we can navigate market volatility, protect shareholder value, and continuously reinvest in areas of highest growth potential, from branded nutraceuticals and pharmaceuticals to digital health and AI-driven discoveries.

II. Milestones & Achievements

The past year has been one of the most pivotal in Cosmos Health's history. We achieved progress on multiple fronts - securing transformative financing, expanding manufacturing capabilities across two continents, scaling our flagship nutraceutical brand into new international markets, and strengthening our innovation pipeline with patents, licensing agreements, and AI-driven R&D.

These milestones are not isolated wins but interconnected achievements that reinforce our strategic vision of building a diversified, resilient, and innovation-driven healthcare ecosystem. Together, they highlight the depth of our progress, the strength of our execution, and the scale of the opportunities that lie ahead.

Harnessing a $300 Million Digital Asset Facility to Power Growth & Innovation

In August 2025, we secured a financing facility from a U.S. institutional investor in the maximum aggregate principal amount of $300 million in the form of senior secured convertible promissory notes. Under the terms of the notes:

72.5% of net proceeds from the sale of each note will be directed toward building a digital treasury reserve, including Ethereum (ETH), Bitcoin (BTC), Solana (SOL) and other digital assets.

The balance will be allocated to working capital and to accelerating growth initiatives, both organic and through acquisitions.

Implementation is already underway, with ETH purchases commenced under the program, marking the beginning of what we believe will become a powerful new financial lever for the company. The Company doesn't view digital-asset treasury reserve as a speculative side venture; it is central to our broader vision.

With capacity to invest over $200 million in digital assets, Cosmos Health is creating one of the largest corporate digital treasury reserves while also retaining significant capital for its core operations. We believe this strategy:

Provides exposure to the upside of global digital asset adoption, increasingly embraced by governments and institutions.

Strengthens our ability to deploy capital across our various business segments.

Acts both as a diversification tool and a catalyst for growth.

Equally important, this approach positions us to explore blockchain's practical applications in healthcare and wellness, creating opportunities to generate value well beyond the balance sheet. By combining financial innovation with operational execution, Cosmos Health is taking a forward-looking approach that reflects the future of both healthcare and technology.

The scale of this facility is substantial for a company of our size. We are grateful for the confidence shown by our lead investor and proud to have structured a transaction of this magnitude. Our focus now is on maximizing its impact, through disciplined treasury management and by channelling our resources into the continued growth of our Company's core healthcare businesses.

Manufacturing Excellence Through Cana Laboratories

Since acquiring Cana in 2023, we have advanced a multi-million-dollar expansion to modernize its wholly owned 54,000-square-foot facility in Athens, Greece, completing Phase I upgrades in 2024. We believe these investments position Cana to generate more than $10 million in recurring annual gross profit at full capacity.

What makes Cana's transformation particularly compelling is the visibility of its long-term contract pipeline consisting of the following:

Pharmex: Five-year agreement for 1.5 million bottles of Ambitasol 1L.

Provident Pharmaceuticals: Order book of 5.02 million units (DE3-SOLE, MIOREL, CALCIFOLIN, DEXA-DOSE, etc.), plus a landmark 10-year contract for 8 million packs across four additional products (Miorelique , BE Union F.C., and Certorun variations).

Humacology: Agreement to manufacture up to 500,000 CBD units.

Medical Pharmaquality: Agreement for 3 million MYCOFAGYL pessaries annually.

With capacity still significantly underutilized, and the potential to further expand output through Phase II upgrades, we believe Cana is positioned to become a cornerstone of our focus on high-margin segments, underpinning long-term growth and driving sustained profitability.

Expanding Manufacturing Across the Atlantic

Our global manufacturing footprint expanded further with the establishment of U.S.-based GMP-certified production in 2025 through our partnership with NOOR Collagen. This dual-hub structure in Europe and the United States reduces cross-border complexities, mitigates tariff exposure, and strengthens supply chain resilience.

Specifically, domestic U.S. manufacturing enables us to:

Capture higher margins and reduce shipping costs.

Accelerate time-to-market for new formulations.

Strengthen our positioning with retailers and e-commerce platforms, where "Made in USA" carries strong trust and regulatory credibility.

Global Expansion of Sky Premium Life

Sky Premium Life, our flagship nutraceutical brand, has become central to our global growth strategy. In 2025, we added more than sixty new formulations, bringing the portfolio to over 150 premium products. The brand continues to expand internationally, demonstrating rapid acceptance and strong repeat demand across multiple regions. Additional formulations are already in the pipeline for 2026, driven by our leading R&D department, ensuring continued innovation and portfolio expansion in the years ahead.

Recent highlights include:

United States: Official launch of U.S. operations entering the $164 billion American nutraceuticals market. Production began with NOOR Collagen, which is expected to generate over $12 million in annualized revenue at approximately 75% gross margins.

UAE: Exclusive distribution agreement with Pharmalink. The initial order of 130,000 units was followed by a repeat order of 80,000 units. Projections exceed 3 million units over five years.

Oman: Agreement signed with Scientific Pharmacy; initial order of 42,000 units supports broader GCC expansion.

Qatar: Exclusive distribution rights secured with multiple partners, including an initial order of $578,460 covering 35 SKUs.

Central Europe (Slovakia, Hungary, Poland, Czechia): Distribution agreement with ZENDON s.r.o. provides access to over 6,000 retail and pharmacy stores across the region, including major chains such as Dr. Max, Rossmann, and Teta Drogerie.

Cyprus: Distribution rollout through Holland & Barrett and local pharmacies via Papaellinas Group, with repeat orders already secured.

Malta: Sales through Holland & Barrett stores, expanding Cosmos Health's retail presence in the Mediterranean region.

Albania: Entry via partnership with Pharma Cell, delivering an initial $300,000 order.

Sales are also growing through leading e-commerce platforms, including Amazon in Germany, Austria, Spain, France, and the United Kingdom, providing direct access to consumers across Europe and further reinforcing Sky Premium Life's digital reach.

Together, these achievements underscore Sky Premium Life's transformation from a regional offering into a truly global brand, trusted by consumers and partners alike in North America, the Middle East, Central Europe, and beyond.

Record Performance at CosmoFarm Wholesale Business

CosmoFarm, our wholesale and logistics arm, continues to deliver record-breaking results. In the first ten months of 2024, CosmoFarm achieved record revenue of approximately $43 million, an 8.62% increase over the same period in 2023. Gross profit rose by 21%, reflecting both higher volumes and improved margins. Based on the pace of growth, CosmoFarm is projected to surpass $50 million in annualized revenue.

Serving over 1,500 pharmacies, it has proven both resilient and scalable, with its wholly owned 29,000-square-foot facility in Athens serving as the operational hub. Investments in automation, procurement, and inventory systems have further boosted efficiency and profitability.

This strong performance has been driven by:

Automation upgrades: Robotic systems including ROWA and SCHAEFER's A-frame, improving order accuracy and fulfilment speed.

Operational enhancements: Better inventory management and procurement processes.

Commercial expansion: A broadened sales and marketing footprint that continues to strengthen customer relationships.

Bolt-on acquisitions: Integration of smaller distribution networks, expanding reach and operational scale.

Together, we believe that these advancements have reinforced CosmoFarm's position as an anchor of stability for Cosmos Health - providing steady revenues, operational resilience, and a scalable platform for further growth across economic cycles.

R&D, Patents, and AI Innovation

Innovation remains at the core of Cosmos Health, and over 2024-2025 our R&D efforts have made meaningful progress. We have advanced our proprietary obesity treatment, CCX0722, beyond laboratory development and into the clinical trial preparation stage, with a potential launch as early as 2026. Designed with patient safety and tolerability in mind, CCX0722 represents one of our most promising opportunities in a global market of growing importance.

At the same time, we have expanded our pipeline and intellectual property across multiple therapeutic areas, including autoimmune diseases, neurology, oncology, and allergies. Many of these advances are powered by Cloudscreen, our AI-enabled drug repurposing platform, which combines advanced computational methods with experimental validation to accelerate discovery. This approach has already generated promising candidates in multiple sclerosis, inflammatory disorders, and allergy therapies.

Key achievements include:

Obesity & Metabolic Disorders: Advanced CCX0722 toward clinical evaluation, positioning for entry into the global weight-management market.

Oncology: Acquired full rights to a WIPO-filed CNS cancer patent; filed new AI-driven patents in gliomas and hematologic malignancies with Cloudpharm and the National Hellenic Research Foundation; and secured exclusive worldwide licenses for two patented anticancer therapies targeting prostate, ovarian, and colorectal cancers.

Autoimmune & Neurological Disorders: Expanded pipeline with Cloudscreen-derived candidates for multiple sclerosis and inflammatory conditions.

Allergy Treatments: Initiated preclinical programs on novel allergy therapies.

Together, these initiatives reflect our dual focus: developing proprietary products with global potential while leveraging scientific innovation to enhance the profitability and differentiation of our portfolio. Every new patent, clinical milestone, and Cloudscreen breakthrough strengthens Cosmos Health's long-term growth profile and underscores our commitment to advancing science for the benefit of patients and shareholders.

Portfolio Strengthening

We believe our portfolio today is broader and stronger than ever. Alongside our flagship Sky Premium Life brand, we have built complementary pillars in wellness and family health through Mediterranation , inspired by the Mediterranean diet, and bio-bebe , a trusted name in infant nutrition.

In 2024, we expanded further into pharmaceuticals with the acquisition of a 10-drug generics portfolio, giving Cosmos Health direct exposure to the $400 billion global generics market. This diversification strengthens our positioning across multiple healthcare segments, from premium nutraceuticals to essential medicines, and provides a stable platform for sustainable, long-term growth.

We have also extended our presence into diagnostics through our collaboration with Virax Biolabs, which now spans Mpox RT-PCR kits (with rights across Greece, Cyprus, Europe, and the GCC region) and Avian Influenza Virus PCR kits (exclusive rights in Greece and Cyprus). These partnerships broaden our exposure to infectious disease testing and reinforce our entry into adjacent high-value markets.

In addition, Cosmos is advancing its proprietary hygiene brands, C-Sept and C-Scrub , which are gaining momentum in both consumer and institutional channels:

United Kingdom: Actively pursuing a potential supply contract with the UK National Health Service (NHS).

Germany: Sales already underway through established distribution partners.

Together, these developments highlight how Cosmos Health is building a diversified, future-ready healthcare group capable of addressing global demand across consumer products, pharmaceuticals, diagnostics, and hygiene solutions.

As both CEO and a long-term shareholder, I want to emphasize my personal commitment. Since the inception of Cosmos Health, I have invested more than $18 million of my own capital into the Company, and I now hold over 6 million shares.

I have continued to make consistent share purchases, including in multiple recent rounds, demonstrating my unwavering conviction in the value we are building together. These are not symbolic gestures but a purposeful long-term commitment which reflects my belief in our strategy, our people, and our future. My interests remain fully aligned with yours.

III. Financial Performance & Outlook

2024 Results Highlighted by Top-Line Growth and Cost Discipline

In 2024, Cosmos Health delivered steady top-line growth while making significant progress in improving efficiency, including meaningful cost-cutting measures.

Revenues increased to $54.43 million, an approximately 2% gain over 2023, supported by expansion in branded products and distribution.

Operating expenses decreased by approximately 24% year over year, with general and administrative costs down 40% and sales and marketing down 71%.