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Chemomab Therapeutics Announces Late-Breaking Oral Presentation of CM-101 Phase 2 Results in Primary Sclerosing Cholangitis at AASLD The Liver Meeting 2024

Key Takeaway: Chemomab Therapeutics announced that the Phase 2 SPRING trial results of CM-101 for primary sclerosing cholangitis (PSC) will be presented orally at the 2024 AASLD The Liver Meeting. The results indicate improved fibrosis biomarkers in patients. The presentation is scheduled for November 18, 2024, by Professor Christopher Bowlus. Chemomab is anticipating further developments, including FDA feedback for its planned Phase 3 trial in 2025.

Market Sentiment Analysis

POSITIVE FACTORS

  • Late-breaking abstract has been selected for oral presentation.
  • Positive results from Phase 2 SPRING trial in PSC.
  • CM-101 shows a favorable safety profile and is well-tolerated.
  • Upcoming FDA feedback and milestones anticipated in early 2025.

Full Press Release Details

TEL AVIV, Israel, Oct. 15, 2024 (GLOBE NEWSWIRE) -- Chemomab Therapeutics Ltd. (Nasdaq: CMMB) (Chemomab), a clinical stage biotechnology company developing innovative therapeutics for fibro-inflammatory diseases with high unmet need, today announced that its late breaking abstract discussing the results of the Phase 2 SPRING trial in primary sclerosing cholangitis (PSC) has been selected for an oral presentation at the American Association for the Study of Liver Disease (AASLD) The Liver Meeting® 2024. The conference will take place in San Diego, California, November 15 – 19, 2024.
Professor Christopher Bowlus, MD, FAASLD, the Lena Valente Professor and Chief of the Division of Gastroenterology and Hepatology at the University of California Davis School of Medicine will give an oral presentation describing data from the double-blinded portion of the Phase 2 SPRING trial assessing CM-101 in individuals with PSC.
Title: CM-101 improved fibrosis biomarkers in patients with primary sclerosing cholangitis: The Phase 2 SPRING Study
Author: Christopher Bowlus, MD
Session: Late Breaking Abstract Parallel Session 1
Session Time: November 18, 2024, 2:00pm – 3:30pm PDT
Presentation Time: November 18, 2024, 2:45 - 3:00pm PT
Publication Number: 5005
Members of the Chemomab senior leadership team will be attending the 2024 AASLD conference. Please reach out to set up a meeting or to learn more about the company.
About Chemomab Therapeutics Ltd.
Chemomab is a clinical stage biotechnology company developing innovative therapeutics for fibro-inflammatory diseases with high unmet need. Based on the unique role of the soluble protein CCL24 in promoting fibrosis and inflammation, Chemomab developed CM-101, a dual activity monoclonal antibody that neutralizes CCL24 activity. In clinical and preclinical studies, CM-101 has been shown to have a favorable safety profile and has been generally well-tolerated, with the potential to treat multiple severe and life-threatening fibro-inflammatory diseases. Chemomab has reported positive results from four clinical trials of CM-101 in patients. Based on recent promising data from its Phase 2 trial in the rare liver disease primary sclerosing cholangitis (PSC), the company expects two upcoming milestones in early 2025, including FDA feedback on the design of its planned PSC Phase 3 registrational trial. CM-101 has received FDA and EMA Orphan Drug and FDA Fast Track designations for PSC. Chemomab’s CM-101 program for the treatment of systemic sclerosis is Phase 2-ready with an open U.S. IND. For more information, visit www.chemomab.com.
Media and Investors:
Consulting Vice President, Investor & Public Relations, Strategic Communications
Phone: +1 917-355-9234

Tags

AASLD The Liver Meeting 2024
Primary Sclerosing Cholangitis

Frequently Asked Questions

What is Chemomab Therapeutics developing?

Chemomab Therapeutics is developing innovative therapeutics for fibro-inflammatory diseases.

When will the AASLD 2024 conference take place?

The AASLD conference will be held from November 15 to 19, 2024.

Who will present at the AASLD 2024 conference?

Professor Christopher Bowlus will present data from the Phase 2 SPRING trial.

What is CM-101 targeting?

CM-101 targets CCL24 to mitigate fibrosis and inflammation in patients.

What designations has CM-101 received?

CM-101 has received FDA and EMA Orphan Drug and FDA Fast Track designations.

Last updated: Oct 15, 2024