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Investor Presentation October 2017 2017 MRI INTERVENTIONS, INC. | 1 Forward Looking Statements Statements herein concerning MRI Interventions, Inc. (the "Company") plans, growth and strategies may include forward-looking

Key Takeaway: Presentation October 2017 2017 MRI INTERVENTIONS, INC. | 1 Forward Looking Statements Statements herein concerning MRI Interventions, Inc. (the "Company") plans, growth and strategies may include forward-looking statements within the context of the federal securities laws. Stat

Full Press Release Details

Presentation October 2017 2017 MRI INTERVENTIONS, INC. | 1
Forward Looking Statements Statements herein concerning MRI Interventions, Inc. (the "Company") plans, growth
and strategies may include forward-looking statements within the context of the federal securities laws. Statements regarding
the Company's future events, developments and future performance, as well as management's expectations, beliefs, plans, estimates
or projections relating to the future, are forward-looking statements within the meaning of these laws. Uncertainties and risks
may cause the Company's actual results to differ materially from those expressed in or implied by forward-looking statements.
Particular uncertainties and risks include those relating to: the Company's ability to obtain additional financing; estimates
regarding the sufficiency of the Company's cash resources; future revenues from sales of the Company's ClearPoint
System products; and the Company's ability to market, commercialize and achieve broader market acceptance for the Company's
ClearPoint System products. More detailed information on these and additional factors that could affect the Company's actual
results are described in the "Risk Factors" section of the Company's Annual Report on Form 10-K for the year
ended December 31, 2016, which has been filed with the Securities and Exchange Commission, and our most recently filed Quarterly
Report on Form 10-Q for the quarter ended June 30, 2017, which will be filed with the Securities and Exchange Commission on or
before August 15, 2017. 2017 MRI INTERVENTIONS, INC. | 2
MRIC: The Platform Company for MRI-Guided Therapies MRI Interventions: Leader in the Delivery of MRI-Guided Therapies Primary
Innovator in the Field, grown out of the Advanced MR department at Johns Hopkins Extensive Intellectual Property position: 70+
issued US patents, 45 international Proven track record for conceiving, developing, commercializing and securing clinical adoption
for our MRI-guided therapy platform Rapidly Growing Commercial Business; Established the Industry Platform for MRI-guided, Minimally-Invasive
Neurosurgery Strong and growing clinical footprint: 48 hospitals in the US Accelerating adoption, revenue growth: 8 successive
quarters of record procedures Current procedures include DBS electrode placement, laser ablation, biopsy, drug delivery MRIC's
platform integrates with products from multiple companies (med device companies, imaging companies, biotechs) Expanding Platform
into Adjacent Areas to Address Additional Unmet Medical Needs Expanding platform into the stroke market; Joint Development Agmt
with Mayo Clinic Expanding our capabilities, adding novel ultrasound ablation technology via Co-Dev Agmt with Acoustic MedSystems;
initial market is pancreatic cancer Leveraging our existing platform, install base and technologies to enable a rapid, cost-effective
path to additional markets 2017 MRI INTERVENTIONS, INC. | 3
Why MRI-Guided Therapies? Image-guided Therapeutic Procedures Have Become a Mainstay in U.S. Healthcare 1.2 Million Arthroscopic
Procedures 1.5 million Fluoroscopic Procedures 4.0 Million Laparoscopic Procedures MRI Guided Therapeutic Procedures are the Next
Step in this Trend Unique capabilities that no other imaging modality can provide High resolution, three-dimensional, continuous,
no radiation MRI-Guided Procedures are Uniquely Positioned to Address Significant Unmet Medical Needs Functional neurological
diseases (e.g., Parkinson's disease, Epilepsy) Untreatable hemorrhagic stroke (e.g., intracerebral hemorrhage) Certain cancers
(e.g., brain, pancreas) 2017 MRI INTERVENTIONS, INC. | 4
Our MRI-Guided Therapy Platform is Currently Being Used to: Implant Neuro Stimulation Products from: Medtronic St. Jude
Medical NeuroPace Place Laser Ablation Probes from: Medtronic-Visualase Monteris Medical Deliver Drugs and Biologics from: Voyager
Medicenna Oxford Biomedica International Stem Cell Corporation MRIC Platform Runs on All Major Scanners: Siemens GE Philips IMRIS
2017 MRI INTERVENTIONS, INC. | 5
Broad and Growing User Base of Leading Neurosurgeons ClearPoint Is Installed in 50 Top US Hospitals
and Growing UC San Francisco San Francisco VA Univ of Michigan Stanford Univ Brigham & Women's UCSF Benioff Childrens
Boston Children's USC Yale Univ UC San Diego Univ of Pitt Med Center Univ of Colo Memorial Sloan Kettering Univ of Utah
Hackensack Univ Med Center Univ of Arizona Nat. Institutes of Health Cook Children's Nat Children's Hospital MD Anderson
Children's Hosp of Philadelphia Methodist Hosp Univ of Virginia Texas Children's Hosp Emory University Riverside Carillion
Nationwide Children's Duke University Children's Mercy Children's of Alabama Kansas Univ Med Center CHOA Scottish
Rite Univ of Wisconsin Willis Knighton Spectrum Health Mayo Clinic Jacksonville Ohio State Univ Miami Children's Univ of
Cincinnati Strong Commercial Sales and Clinical Support Teams in Place 2017 MRI INTERVENTIONS, INC. | 6
Foundation of Our Platform: ClearPoint Neuro Navigation System 2017 MRI INTERVENTIONS, INC. | 7
Without ClearPoint, Minimally Invasive Neuro Procedures Are Performed "Blind" Conventional Stereotactic
Procedure ClearPoint Neuro Procedure No real time images images from earlier in the day or week 2017 MRI INTERVENTIONS,
ClearPoint Neuro Navigation System: MRI-Guided NeuroSurgical Platform ClearPoint Components: Capital Sale Recurring
Revenue Reusable Hardware Components Integrated Software Single-Use, Disposable Components Emory University Hospital Univ.
of California San Francisco Univ. of Pittsburgh Medical Center Medical Center 2017 MRI INTERVENTIONS, INC. | 9
Details on Our ClearPoint Neuronavigation System Platform ClearPoint Procedure Overview: ClearPoint Video ClearPoint Video
Entry and Trajectory Alignment and Insertion 2017 MRI INTERVENTIONS, INC. | 10
Multiple Clinical Applications for Our ClearPoint System Platform Electrode Placement and Laser Ablation Drug Delivery
Significant Unmet Medical Parkinson's disease, Epilepsy, Brain Tumor, Dystonia Enabling Multiple Therapies from Multiple
Companies: Electrode Placement: Medtronic, St. Jude, Neuropace Laser Ablation: MDT/Visualase, Monteris Drug Delivery: Voyager,
Medicenna, Oxford Biomedica, Int'l Stem Cell (1) Laser Ablation - MR Thermometry is an MRI-based functionality available
on most MR scanner platforms and it is a feature built into products from several third party vendors. The ClearPoint system enables
MRI-guided procedures and allows physicians to use this inherent MR capability during a procedure. (2) Drug Delivery - The SmartFlow
cannula received 510(k) clearance for injection of cytarabine, a chemotherapy drug, to the ventricles or removal of CSF from the
ventricles during intracranial procedures. Delivery of other therapeutic agents, and delivery of agents to other areas of the
brain, using the SmartFlow cannula is investigational. 2017 MRI INTERVENTIONS, INC. | 11
Strong Business Model for Our Core MRI-Guided Navigation Platform ClearPoint Hardware/Software: $100,000 - $150,000 ASP
ClearPoint Disposables: ~$7,500 ASP per procedure with strong margins Recurring revenue from the sale of disposables Procedures
covered by existing inpatient DRG reimbursement codes Same razor/razorblade model applies to future product sales 2017
MRI INTERVENTIONS, INC. | 12
ClearPoint Neurosurgical Procedure Growth 800 Procedures 650-700 CAGR, 2013 2016: 46% 700 600 Q1,
2017: 146 500 Procedures 400 Q2, 2017: 162 Procedures 300 Nine quarters in a 200 row of procedure 100 growth 0 2013 2014 2015
2016 2017 Outlook 2017 MRI INTERVENTIONS, INC. | 13
Expanding Our Platform: New Procedural Applications 2017 MRI INTERVENTIONS, INC. | 14
Expanding MRIC's MRI-Guided Therapy Platform Benefits Larger Patient Populations First, MRIC established the
Capability of the Platform Began with Electrode Placement (DBS) Parkinson's disease, dystonia Expanded to Biopsy
Brain Tumor Expanded to Laser Ablation Probe Placement Epilepsy and Brain Tumor Expanded to Drug Delivery Parkinson's Disease
and Brain Tumor now, Expanding the Reach of the MRI-Guided Platform Expanding Adding Novel Ablation Technology to Platform
Initial focus in Pancreatic Cancer 2017 MRI INTERVENTIONS, INC. | 15
Expanding into the Stroke Market Leveraging Existing Capabilities and Install Base Expanding the Reach of the MRIC Platform
into the Stroke Market Joint Development Agreement with Mayo Clinic Dr. Bernard Bendok, Chair of Neurosurgery, Mayo Arizona
Large Stroke Market 5th leading cause of death in US Leading cause of permanent disability Affects 800,000 people in the
US every year Initial Stroke Product (ClearAway ) Targets Intracerebral Hemorrhage (ICH) Only major stroke subtype w/o
clearly effective therapy major unmet medical need Affects 80,000 to 100,000 people in the US each year MRIC market opportunity
is 12,000 to 15,000 cases/year 2017 MRI INTERVENTIONS, INC. | 16
Our MRI-Guided Approach to Intra Cerebral Hemorrhagic Stroke Current Approaches for Hemorrhage Removal and Decompression are
Inadequate: Open craniotomy provides visibility but is highly invasive, destroys brain tissue Minimally Invasive approach
has very limited ability to quantify volume reduction of the hemorrhage or monitor subsequent bleeds Our Unique ClearAway MRI-Guided
Therapy Approach to ICH Detailed, continuous, high resolution, 3 dimensional visibility Minimally invasive approach Expected
Path to Market Builds directly on our ClearPoint Platform ClearPoint software and hardware; SmartFrame Hemorrhage aspiration
components Potential 510(k) regulatory path Projected market introduction as soon as 12-18 months U.S. Market Opportunity = $72
million to $90 million 95% of Our Existing ClearPoint Adult Sites Have a Stroke Program! 2017 MRI INTERVENTIONS,
Expanding our Platform with a Novel Ablation Technology Co-Development Agreement Will Add Additional Capabilities License
and Co-Development Agreement with Acoustic MedSystems (AMS) Leading developer of ultrasound ablation technologies and systems
Base technology has 510k clearance Initial license areas: WW Excl. for Pancreatic Cancer, Excl. Option for Brain Applications
AMS Ultrasound Technology Provides Unique Capabilities Directional Ablation over Other Ablative Energy Sources
Precision ablation over small and large areas Directional and depth control "Protected Zone" between transducer
and ablated tissue AMS Ultrasound Technology Works with MRI Interventions' Technology MRI-friendly components Enhanced
by real-time, MRI-guidance Can incorporate real-time MRI-thermometry 2017 MRI INTERVENTIONS, INC. | 18
Co-Development Focused First on Pancreatic Cancer Market Pancreatic Cancer Market Major Unmet Medical Need 50,000 patients
in US diagnosed annually 10,000 to 15,000 cases annually are localized, non-metastatic tumors, but untreatable because of the
tumor location Our Therapeutic Approach Targets Untreatable Tumors pancreas Vascular access to get near the tumor Apply
ultrasound energy to ablate the tumor Destroy the tumor Preserve the vessel Expected Path to Market Begin limited human
use of existing AMS products in September Projected market introduction of integrated pancreatic cancer product as soon as 18
- 24 months Potential 510(k) regulatory path U.S. Market Opportunity = $50 million to $75 million 2017 MRI INTERVENTIONS,
Strong Pipeline of New Products to Add to our Existing Products Leveraging our MRI-Guided Therapy Platform Projected
Last updated: Oct 3, 2017