Clinical Results from CollPlant's

Clinical Results from CollPlant's

Advanced Wound Care Product VergenixFG to be Presented at European Wound Management Association Conference

Rehovot, June 4, 2019, CollPlant (NASDAQ:CLGN),

a regenerative medicine company, today announced that the results from a clinical study conducted with its VergenixFG advanced

wound care product will be presented at the 29th Conference of the European Wound Management Association (EWMA).

The EWMA conference will take place from

June 5-7, 2019 in Gothenburg, Sweden. It is one of the largest wound conferences in the world, gathering the European and international

wound management communities with the common goal of improving patient wound care.

On Friday June 7, 2019, from 10.30 AM

- 11.30 AM, Dr. Eyal Shapira from the department of Plastic Surgery, Assaf Harofeh Medical Center, Israel, will present clinical

results published in Wounds, a peer reviewed journal focused on wound care and wound research. The abstract titled, "A novel

recombinant human collagen-based flowable matrix for chronic lower limb wound management: first results of a clinical trial"

presents data from a previously reported independent study conducted by physicians at several wound care medical clinics and hospitals

in Israel. Data showed that VergenixFG resulted in 94% median wound area reduction within 4-weeks in patients with chronic lower

"We look forward to participating

at the EWMA conference and attending Dr. Shapira's presentation which will demonstrate remarkable wound closure rates achieved

with single application use of VergenixFG. We will also have an exhibition booth where we will have the opportunity to interact

with physicians, distributors, potential strategic partners, and to show our products. VergenixFG is commercially available in

Europe, and we are expanding our distribution network to other territories," stated CollPlant CEO, Yehiel Tal.

CollPlant is a regenerative medicine company

focused on 3D bioprinting of tissues and organs, medical aesthetics, and on developing and commercializing tissue repair products

for orthobiologics, and advanced wound care markets. Our products are based on our rhCollagen (recombinant human collagen) that

is produced with CollPlant's proprietary plant based genetic engineering technology.

Our products address indications for the

diverse fields of organ and tissue repair, and are ushering in a new era in regenerative medicine. Our flagship rhCollagen BioInk

product line is ideal for 3D bioprinting of tissues and organs. We recently entered into a licensing agreement with United Therapeutics,

whereby United Therapeutics is using CollPlant's BioInks in the manufacture of 3D bioprinted lungs for transplant in humans.

CollPlant's unique Vergenix line of rhCollagen products includes a soft tissue repair matrix for treating tendinopathy and

a wound repair matrix to promote a rapid optimal healing of acute and chronic wounds.

For more information about CollPlant,

visit http://www.collplant.com

Safe Harbor Statements

This press release may include forward-looking

statements. Forward-looking statements may include, but are not limited to, statements relating to CollPlant's objectives

plans and strategies, as well as statements, other than historical facts, that address activities, events or developments that

CollPlant intends, expects, projects, believes or anticipates will or may occur in the future. These statements are often characterized

by terminology such as "believes," "hopes," "may," "anticipates," "should,"

"intends," "plans," "will," "expects," "estimates," "projects,"

"positioned," "strategy" and similar expressions and are based on assumptions and assessments made in

light of management's experience and perception of historical trends, current conditions, expected future developments and

other factors believed to be appropriate. Forward-looking statements are not guarantees of future performance and are subject

to risks and uncertainties that could cause actual results to differ materially from those expressed or implied in such statements.

Many factors could cause CollPlant's actual activities or results to differ materially from the activities and results anticipated

in forward-looking statements, including, but not limited to, the following: the Company's history of significant losses,

its ability to continue as a going concern, and its need to raise additional capital and its inability to obtain additional capital

on acceptable terms, or at all; the Company's expectations regarding the timing and cost of commencing clinical trials with

respect to tissues and organs which are based on its rhCollagen based BioInk, dermal fillers for aesthetics, VergenixSTR, and

VergenixFG; the Company's ability to obtain favorable pre-clinical and clinical trial results; regulatory action with respect

to rhCollagen based BioInk, dermal fillers for aesthetics, VergenixSTR, and VergenixFG including but not limited to acceptance

of an application for marketing authorization, review and approval of such application, and, if approved, the scope of the approved

indication and labeling; commercial success and market acceptance of the Company's rhCollagen based BioInk, dermal fillers

for aesthetics, VergenixSTR, and VergenixFG; the Company's ability to establish sales and marketing capabilities or enter

into agreements with third parties and its reliance on third party distributors and resellers; the Company's ability to

establish and maintain strategic partnerships and other corporate collaborations; the Company's reliance on third parties

to conduct some or all aspects of its product manufacturing; the scope of protection the Company is able to establish and maintain

for intellectual property rights and the Company's ability to operate its business without infringing the intellectual property

rights of others; the overall global economic environment; the impact of competition and new technologies; general market, political,

and economic conditions in the countries in which the Company operates; projected capital expenditures and liquidity; changes

in the Company's strategy; and litigation and regulatory proceedings. More detailed information about the risks and uncertainties

affecting CollPlant is contained under the heading "Risk Factors" included in CollPlant's most recent annual

report on Form 20-F filed with the SEC, and in other filings that CollPlant has made and may make with the SEC in the future.

The forward-looking statements contained in this press release are made as of the date of this press release and reflect CollPlant's

current views with respect to future events, and CollPlant does not undertake and specifically disclaims any obligation to update

or revise any forward-looking statements, whether as a result of new information, future events or otherwise.