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Compugen to Present New Clinical Data Showing Preliminary Anti-Tumor Activity of COM701 Triple Combination in Recurrent MSS-Metastatic Endometrial Cancer at ASCO 2023

Key Takeaway: Compugen Ltd. announced that it will present new clinical data on COM701 in combination with BMS-986207 and nivolumab at the upcoming ASCO annual meeting. This presentation will focus on the preliminary anti-tumor activity of this combination treatment for patients with recurrent, metastatic MSS endometrial cancer. The session is scheduled for June 5, 2023, and may reveal significant insights into the efficacy of this innovative therapeutic approach.

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POSITIVE FACTORS

  • Compugen will present new clinical data showing anti-tumor activity.
  • The data involves a promising triple combination treatment.
  • This presentation highlights Compugen's innovative research in cancer therapies.

Full Press Release Details

HOLON, Israel, April 27, 2023 /PRNewswire/ -- Compugen Ltd. (Nasdaq: CGEN) (TASE:CGEN), a clinical-stage cancer immunotherapy company and a pioneer in computational target discovery, today announced that it will present new clinical data on COM701 in triple combination with BMS-986207 (anti-TIGIT) and nivolumab in metastatic endometrial cancer at the American Society of Clinical Oncology (ASCO) annual meeting on June 2-6, 2023, in Chicago, Illinois.
Poster Presentation Details:
Title: Preliminary antitumor activity of the combination of COM701 + BMS-986207 + nivolumab in patients with recurrent, metastatic MSS endometrial cancer
Abstract Number: 5595
Session Title: Gynecologic Cancer
Lead Author: Rasco, D, MD
Date: Monday, June 5, 2023
Compugen is a clinical-stage therapeutic discovery and development company utilizing its broadly applicable predictive computational discovery capabilities to identify new drug targets and biological pathways for developing cancer immunotherapies. Compugen has developed two proprietary product candidates: COM701, a potential first-in-class anti-PVRIG antibody and COM902, a potential best-in-class antibody targeting TIGIT for the treatment of solid tumors. Compugen also has a clinical stage partnered program, rilvegostomig (previously AZD2936), a PD-1/TIGIT bi-specific derived from COM902, that is in Phase 2 development by AstraZeneca through a license agreement for the development of bi-specific and multi-specific antibodies. In addition, the Company's therapeutic pipeline of early-stage immuno-oncology programs consists of programs aiming to address various mechanisms of immune resistance. The most advanced program, COM503 is advancing in IND enabling studies. COM503 is a potential first-in-class, high affinity antibody which blocks the interaction between IL-18 binding protein and IL-18, thereby freeing natural IL-18 to inhibit cancer growth in the tumor microenvironment. Compugen is headquartered in Israel, with offices in San Francisco, CA. Compugen's shares are listed on Nasdaq and the Tel Aviv Stock Exchange under the ticker symbol CGEN.
Yvonne Naughton, Ph.D.
Head of Investor Relations and Corporate Communications
Email: [email protected]
Tel: +1 (628) 241-0071
SOURCE Compugen Ltd.

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Frequently Asked Questions

What is COM701 used for?

COM701 is a potential first-in-class anti-PVRIG antibody for cancer treatment.

When will the new clinical data on COM701 be presented?

The data will be presented on June 5, 2023, at the ASCO annual meeting.

What combination will be studied with COM701?

COM701 will be studied with BMS-986207 and nivolumab in endometrial cancer.

Who is the lead author of the presentation?

The lead author is Dr. D. Rasco.

What is Compugen's primary focus?

Compugen focuses on discovering and developing cancer immunotherapies.

Last updated: Apr 27, 2023