Full Press Release Details
Cullinan Oncology Provides Corporate Update and
Reports Third Quarter 2021 Financial Results
Cullinan Pearl clinical update, including data from patients enrolled in the Phase 2a expansion 100 mg BID cohort, planned for fourth quarter 2021
Cullinan MICA and Cullinan Florentine programs to advance into clinical trials by year end 2021
Strong balance sheet with cash and investments of $445.4 million
Cambridge, MA, November 9, 2021 Cullinan Oncology, Inc. (Nasdaq: CGEM), a biopharmaceutical company focused on developing a
diversified pipeline of targeted therapies, today reported on recent and upcoming business highlights and announced its financial results for the third quarter ended September 30, 2021.
Our organization has made great progress advancing our pipeline of novel, targeted oncology programs across multiple modalities, positioning us to
deliver on our 2021 milestones, stated Nadim Ahmed, Chief Executive Officer of Cullinan Oncology. We are encouraged by the clinical profile emerging from our lead program, Pearl (CLN-081), in
heavily pretreated advanced NSCLC patients that harbor EGFR exon 20 insertion mutations and are looking forward to providing a clinical update from our ongoing Phase 1/2a trial later this quarter. We are also excited to advance Cullinan MICA and
Cullinan Florentine into clinical trials this quarter. With our evolution into a late stage oncology company, we are utilizing our significant financial resources of over $445 million of cash and investments on hand to advance multiple programs
into the clinic across a wide range of cancer indications.
Portfolio Highlights
Third Quarter 2021 Financial Results
Cullinan Oncology is a biopharmaceutical company with a diversified pipeline of targeted therapeutic candidates across multiple modalities.
The Company s strategy is to focus on advanced stage assets with novel technology platforms and differentiated mechanisms, developed through both internal discovery and external collaboration. Learn more about Cullinan at
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. These forward-looking
statements include, but are not limited to, express or implied statements regarding Cullinan s beliefs and expectations regarding our preclinical and clinical development plans, clinical trial designs, clinical and therapeutic potential, and
strategy of our product candidates, including but not limited to: the timing and success of our planned preclinical and clinical development of our programs, including for CLN-081, CLN-619, and CLN-049, and the timing and success of our planned regulatory submissions; our expectations and beliefs around the safety and activity of CLN-081 in our Phase 1/2a trial in patients with NSCLC harboring EGFRex20ins mutations that have had at
least one prior treatment; our ability to evaluate strategic opportunities to accelerate development timelines; the presentation of additional data at upcoming scientific conferences in 2021; our
ability to optimize the impact of our collaborations and license agreements with external parties; our ability to continue our growth; and our expectations regarding our use of capital. The words anticipate, believe,
continue, could, estimate, expect, hope, intend, may, plan, potential, predict, project, target,
should, would, and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words.
Any forward-looking statements in this press release are based on management s current expectations and beliefs of future events, and are subject to
known and unknown risks and uncertainties that may cause our actual results, performance or achievements to be materially different from any expressed or implied by the forward-looking statements. These risks include, but are not limited to, the
following: uncertainty regarding the timing and results of regulatory submissions; success of our clinical trials and preclinical studies; risks related to our ability to protect and maintain our intellectual property position; risks related to
manufacturing, supply, and distribution of our product candidates; risks related to the impact of COVID-19 affecting countries or regions in which we have operations or do business, including potential
negative impacts on our employees, customers, supply chain and production as well as global economies and financial markets; the risk that any one or more of our product candidates, including those that are
co-developed, will not be successfully developed and commercialized; the risk that the results of preclinical studies or clinical studies will not be predictive of future results in connection with future
studies; and success of any collaboration, partnership, license or similar agreements. These and other important risks and uncertainties discussed in our filings with the Securities and Exchange Commission (SEC), including under the caption
Risk Factors in our most recent Annual Report on Form 10-K and subsequent filings with the SEC, could cause actual results to differ materially from those indicated by the forward-looking
statements made in this press release. While we may elect to update such forward-looking statements at some point in the future, we disclaim any obligation to do so, even if subsequent events cause our views to change, except to the extent required
by law. These forward-looking statements should not be relied upon as representing our views as of any date subsequent to the date of this press release. Moreover, except as required by law, neither Cullinan nor any other person assumes
responsibility for the accuracy and completeness of the forward-looking statements included in this press release. Any forward-looking statement included in this press release speaks only as of the date on which it was made.
Cullinan Oncology, Inc.
Consolidated Balance Sheets (Unaudited)
(in thousands, except shares and per share amounts)
| December 31, 2020 | September 30, 2021 | |||||||
| Assets | ||||||||
| Current assets: | ||||||||
| Cash and cash equivalents | $ | 168,198 | $ | 88,105 | ||||
| Short-term investments | 42,008 | 232,939 | ||||||
| Prepaid expenses and other current assets | 2,072 | 7,794 | ||||||
| Total current assets | 212,278 | 328,838 | ||||||
| Property and equipment, net | 130 | 89 | ||||||
| Other assets | 2,300 | 147 | ||||||
| Long-term investments | 124,330 | |||||||
| Total assets | $ | 214,708 | $ | 453,404 | ||||
| Liabilities and Stockholders Equity | ||||||||
| Current liabilities: | ||||||||
| Accounts payable | $ | 9,679 | $ | 2,024 | ||||
| Accrued expenses and other current liabilities | 4,641 | 5,839 | ||||||
| Total current liabilities | 14,320 | 7,863 | ||||||
| Long-term liabilities: | ||||||||
| Deferred rent | 74 | 67 | ||||||
| Total liabilities | 14,394 | 7,930 | ||||||
| Commitments and contingencies | ||||||||
| Stockholders equity: | ||||||||
| Common stock, $0.0001 par value, 34,900,878 and 150,000,000 shares authorized as of December 31, 2020 and September 30, 2021, respectively; 29,831,125 and 43,660,909 shares issued and outstanding as of December 31, 2020 and September 30, 2021, respectively. | 3 | 4 | ||||||
| Additional paid-in capital | 292,348 | 569,835 | ||||||
| Accumulated other comprehensive loss | (2 | ) | (58 | ) | ||||
| Accumulated deficit | (93,339 | ) | (126,395 | ) | ||||
| Total Cullinan stockholders equity | 199,010 | 443,386 | ||||||
| Noncontrolling interests | 1,304 | 2,088 | ||||||
| Total stockholders equity | 200,314 | 445,474 | ||||||
| Total liabilities and stockholders equity | $ | 214,708 | $ | 453,404 |
Cullinan Oncology, Inc.
Consolidated Statements of Operations and Comprehensive Loss (Unaudited)
(in thousands, except shares and per share amounts)
| Three Months Ended September 30, | Nine Months Ended September 30, | |||||||||||||||
| 2020 | 2021 | 2020 | 2021 | |||||||||||||
| License revenue | $ | $ | $ | $ | 18,943 | |||||||||||
| Operating expenses: | ||||||||||||||||
| Research and development | 9,913 | 12,680 | 26,582 | 36,873 | ||||||||||||
| General and administrative | 1,586 | 5,695 | 4,580 | 15,677 | ||||||||||||
| Total operating expenses | 11,499 | 18,375 | 31,162 | 52,550 | ||||||||||||
| Loss from operations | (11,499 | ) | (18,375 | ) | (31,162 | ) | (33,607 | ) | ||||||||
| Other income (expense): | ||||||||||||||||
| Interest income | 185 | 118 | 809 | 340 | ||||||||||||
| Other income (expense), net | (2 | ) | 1 | (12 | ) | |||||||||||
| Net loss | (11,314 | ) | (18,259 | ) | (30,352 | ) | (33,279 | ) | ||||||||
| Net loss attributable to noncontrolling interest | (1,456 | ) | (909 | ) | (6,899 | ) | (223 | ) | ||||||||
| Net loss attributable to common stockholders of Cullinan | $ | (9,858 | ) | $ | (17,350 | ) | $ | (23,453 | ) | $ | (33,056 | ) | ||||
| Net loss per share, basic and diluted | $ | (0.50 | ) | $ | (0.40 | ) | $ | (1.21 | ) | $ | (0.76 | ) | ||||
| Total weighted-average shares used in computing net loss per share, basic and diluted | 19,721,992 | 43,438,861 | 19,453,479 | 43,254,230 | ||||||||||||
| Comprehensive loss: | ||||||||||||||||
| Net loss | $ | (11,314 | ) | $ | (18,259 | ) | $ | (30,352 | ) | $ | (33,279 | ) | ||||
| Unrealized gain/(loss) on investments | (144 | ) | 57 | 63 | (56 | ) | ||||||||||
| Comprehensive loss | (11,458 | ) | (18,202 | ) | (30,289 | ) | (33,335 | ) | ||||||||
| Comprehensive loss attributable to noncontrolling interest | (1,456 | ) | (909 | ) | (6,899 | ) | (223 | ) | ||||||||
| Comprehensive loss attributable to Cullinan | $ | (10,002 | ) | $ | (17,293 | ) | $ | (23,390 | ) | $ | (33,112 | ) |