Kevin D. Green Vice President, Finance & CFO Cerus Corporation (925) 288-6138 Cerus Corporation Reports Third Quarter 2013 Results Q3 product revenue of $10.5 million; reiterating $41-43 million annual revenue g

Vice President, Finance & CFO

Cerus Corporation Reports

Third Quarter 2013 Results

CONCORD, CA, October 29, 2013 -

Cerus Corporation (NASDAQ: CERS) today announced financial results for the third quarter and nine months ended September 30, 2013.

quarter, we continued to submit INTERCEPT plasma and platelet PMA modules on schedule, and look forward to completing these submissions in November 2013 and March 2014, respectively, said William Obi Greenman, Cerus president

and chief executive officer. Our $10.5 million in Q3 product revenue provides steady progress toward our projected full year revenue guidance of $41-$43 million.

Product revenue for the third quarter of 2013

was $10.5 million, a 28% increase over the third quarter of 2012. Increased deployment of illuminators in several geographies, as well as elevated sales of plasma disposable kits and to a lesser extent, a stronger Euro compared to the U.S. dollar,

drove third quarter revenue growth.

Product revenue for the first nine months of 2013 was $30.4 million, and represented a 16% increase from the same

period in 2012. The increase in product revenue during the first nine months of 2013 over 2012 was driven primarily by increased demand for our INTERCEPT products, particularly plasma disposable kits and to a lesser extent, a stronger Euro compared

product sales for the third quarter of 2013 were 35%, compared to 47% for the third quarter of 2012. Gross margins during the third quarter of 2013 were negatively impacted by certain period charges and the mix of products sold relative to the prior

year. Gross margins were 42% for the first nine months of 2013, compared to 41% for the same period in 2012.

Total operating expenses for the third quarter of 2013 were $12.1 million, compared to $8.2 million for the third quarter of 2012; and $33.3 million for the

nine months ended September 30, 2013 compared to $24.5 million for the same period in the prior year. The

year-over-year increase in operating expenses for both the three and nine months ended September 30, was due primarily to regulatory activities for the preparation and submission activities

supporting the Company s PMA submissions for INTERCEPT plasma and platelets, costs for the clinical activities regarding the Company s red blood cell program and increases in selling, general and administrative expenses in support of the

existing European commercial business and preparatory market research activities for a potential U.S. launch of the INTERCEPT Blood System for plasma and platelets. The company expects these activities to continue to drive increasing operating

Operating and Net Loss

during the third quarter of 2013 were $8.4 million, compared to $4.3 million during the third quarter of 2012, and $20.5 million compared to $13.7 million for the nine months ended September 30, 2013 and 2012, respectively. Despite the

increased product revenues reported during both the three and nine months ended September 30, 2013 compared to 2012, operating losses widened due to the increased investments made in support of our PMA submission activities and our clinical

activities with respect to our red blood cell program during the same periods.

Net loss for the third quarter of 2013 was $20.5 million, or $0.29 per

share, compared to a net loss of $3.5 million, or $0.08 per diluted share, for the third quarter of 2012. Net loss for the first nine months of 2013 was $37.5 million, or $0.56 per share, compared to a net loss of $14.2 million, or $0.26 per share,

for the same period of 2012. Net losses were impacted by the mark-to-market adjustments of the Company s outstanding warrants to fair value. These adjustments resulted in non-cash charges of $12.4 million during the third quarter of 2013

compared to a gain of $0.9 million during the third quarter of 2012 and non-cash charges of $16.8 million compared to non-cash gains of $0.1 million during the nine months ended September 30, 2013 and 2012, respectively.

Cash and Cash Equivalents

At September 30, 2013,

the Company had cash and cash equivalents and short-term investments of $53.3 million compared to $26.7 million at December 31, 2012 and $58.2 million at June 30, 2013. The Company s $7.0 million revolving line of credit remains

outstanding with approximately $3.4 million available for future borrowing.

QUARTERLY CONFERENCE CALL

The Company will host a

conference call and webcast at 4:15 p.m. Eastern time today to discuss its financial results and provide a general business overview and outlook. To access the live webcast, please visit the Investor Relations page of the Cerus website at

http://www.cerus.com/ir. Alternatively, you may access the live conference call by dialing 866-235-9006 (U.S.) or 631-291-4549 (international).

A replay will be available on the company s web site, or by dialing 855-859-2056 (U.S.) or 404-537-3406

(international) and entering conference ID number 31979526. The replay will be available approximately three hours after the call through November 11, 2013.

Cerus Corporation is a biomedical

products company focused in the field of blood safety. The company s INTERCEPT Blood System has been demonstrated to inactivate a broad range of viruses, bacteria and parasites that may be present in donated blood, including established threats

such as hepatitis B and C, HIV, West Nile virus and bacteria, as well as emerging pathogens such as influenza, malaria and dengue. Cerus currently markets and sells the INTERCEPT Blood System for both platelets and plasma in Europe, the Commonwealth

of Independent States, the Middle East and selected countries in other regions around the world. In the United States, Cerus is seeking regulatory approval of the INTERCEPT Blood System for plasma and platelets. The INTERCEPT red blood cell system

is in clinical development. See http://www.cerus.com for more information.

INTERCEPT and the INTERCEPT Blood System are trademarks of Cerus Corporation.

Forward-Looking Statements

historical statements contained herein, this press release contains forward-looking statements concerning Cerus products, prospects and results, including statements concerning Cerus expectations regarding future sales growth and its

2013 revenues, the anticipated timing, completion and success of modular PMA submissions to the FDA for the INTERCEPT Blood System for plasma and platelets, the potential U.S. commercial launch of the INTERCEPT Blood System for plasma and platelets,

future operating expenses, research and development activity and the expenses related thereto, marketing activity and expenses in support of Cerus planned commercialization activities, and the continued availability of Cerus revolving

line of credit. Actual results could differ materially from these forward-looking statements as a result of certain factors, including, without limitation, risks associated with the commercialization and market acceptance of, and customer demand

for, the INTERCEPT Blood System, the uncertain and time-consuming regulatory process, Cerus ability to successfully conduct its ongoing clinical trials for the red blood cell system in the anticipated timeframes, or at all, the fact that Cerus

may encounter unanticipated difficulties complying with the prescribed submission timing or other modular PMA requirements related to the INTERCEPT Blood System for plasma and/or platelets, the fact that Cerus may be required to conduct additional

clinical development in support of its modular PMA submissions for plasma and/or platelets, and that if additional clinical development is required it may require funding that Cerus does not have and could significantly delay or preclude regulatory

approval of the INTERCEPT Blood System for plasma and platelets in the United States, adverse market and economic conditions, adverse fluctuations in foreign exchange rates, Cerus reliance on third parties to market, sell, distribute and

maintain its products, Cerus lack of commercialization experience in the United States and its ability to establish, or contract with third parties to establish, sales, marketing and other sufficient capabilities to potentially market and sell

the INTERCEPT Blood System for plasma and platelets in the United States, Cerus ability to comply with applicable regulatory guidelines and requirements with respect to the marketing and manufacturing of products in the United States,

Cerus ability to maintain an effective manufacturing supply chain, Cerus ability to continue to comply with the financial and other covenants under its revolving line of credit, as well as other risks detailed in Cerus filings with

the Securities and Exchange

Commission, including Cerus Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2013 filed with the SEC on August 2, 2013. Cerus disclaims any obligation or

undertaking to update or revise any forward-looking statements contained in this press release.

Financial Tables Attached

CONDENSED CONSOLIDATED UNAUDITED STATEMENTS OF OPERATIONS

(in thousands except per share information)

CONDENSED CONSOLIDATED UNAUDITED BALANCE SHEETS