Full Press Release Details
Medical Technology Holdings Files Patent on AmnioStem Stroke Therapy
Collaboration between Stem Cell Clinician, Neurologist,
and Cell Therapy Developer Results in Novel Regenerative Approach to Stroke
PHOENIX and SAN DIEGO, Dec. 13, 2016 /PRNewswire/ -- Creative
Medical Technology Holdings (the "Company") (OTCQB:CELZ) announced today filing of US patent application #62/400557
entitled "Treatment of Stroke by Amniotic Fluid Derived Stem Cell Conditioned Media and Products Derived Thereof."
The patent application covers the use of the Company's
newly licensed AmnioStem stem cell as a production means for generation of nanoparticles termed "exosomes," which regenerate
damaged brain tissue after stroke. The AmnioStem stem cell is subject to issued US patent #7,569,385 and was licensed exclusively
from University of California San Diego ("UCSD").
"We are pleased at the successful fruits of this ongoing
collaboration, which provides novel stem cell based therapeutic options by using products derived from stem cells as opposed to
the stem cells themselves," said Amit Patel, MD, MSc, Head of Regenerative Medicine and Tissue Engineering at the University
of Utah, and co-inventor of the patent.
The patent provides means of leveraging growth factors and nucleic
acids generated by AmnioStem stem cells, in order to provide a "drug like" product that overcomes many of the hurdles
associated with administration of stem cells.
"It is known that intravenous injection of stem cells
usually results in accumulation in lungs, leading to reduced therapeutic efficacy. Concentrating and purifying regenerative factors
produced by this unique stem cell type will accelerate development of this novel therapy, as well as develop combination therapies
to provide the highest probability of success to patients suffering from this debilitating condition," said Santosh Kesari,
MD, PhD Chair and Professor of Department of Translational Neurosciences and Neurotherapeutics at Pacific Neuroscience Institute
and John Wayne Cancer Institute at Providence Saint John's Health Center in Santa Monica, CA.
"We are honored to have such an accomplished team which
addresses problems from an unbiased and multidisciplinary perspective," said Timothy Warbington, President and CEO of Creative
Medical Technology Holdings. "By leveraging our intellectual, corporate, and developmental resources, we aim to accelerate
finding treatments and potential cures for debilitating neurological disorders.
About Creative Medical Technology Holdings
Creative Medical Technology Holdings, Inc. is a clinical stage
biotechnology company currently trading on the OTCQB under the ticker symbol CELZ. For further information about the company go
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Actual results may differ materially from those currently anticipated in such statements. See the periodic and other reports filed
by Creative Medical Technology Holdings, Inc. with the Securities and Exchange Commission and available on the Commission's
website at www.sec.gov.
Creative Medical Technology Holdings, Inc.
Timothy Warbington, CEO & President
SOURCE Creative Medical Technology Holdings, Inc.