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Creative Medical Technology Holdings Expands Adult Stem Cell Therapeutic Platform to Combat Female Infertility Caused by Premature Ovarian Failure Company Files Patent on Rejuvenating Ovaries through Use of Endothelial P

Key Takeaway: Creative Medical Technology Holdings Expands Adult Stem Cell Therapeutic Platform to Combat Female Infertility Caused by Premature Ovarian Failure Company Files Patent on Rejuvenating Ovaries through Use of Endothelial Progenitor Cell Stem Cells PHOENIX, Arizona, August 24,

Full Press Release Details

Creative Medical Technology Holdings
Expands Adult Stem Cell Therapeutic Platform to Combat
Female Infertility Caused by Premature Ovarian Failure
Company Files Patent on Rejuvenating
Ovaries through Use of Endothelial Progenitor Cell Stem Cells
PHOENIX, Arizona, August 24, 2016 -Creative Medical Technology
Holdings, Inc. (OTCQB: CELZ) announced the filing of a patent application disclosing means of regenerating failing ovaries through
use of a particular type of stem cell extracted from patient's own tissues.
The patent-pending technology utilizes cells extracted from
the patient's own bone marrow and processed in a manner to select for stem cells that participate in generation of new blood
vessels termed "Endothelial Progenitor Cells" (EPC). By using EPC alone, or in combination with other cells such as
mesenchymal stem cells, the treatment aims to overcome scar tissue and factors that inhibit oocyte viability.
The Company seeks to apply its clinical-stage autologous bone
marrow stem cell experiences to patients suffering from a specific type of Premature Ovarian Failure, in which menopause occurs
at an accelerated rate. Premature Ovarian Failure is believed to affect 1 in 100 women under the age of 40, and unfortunately,
no effective treatment exists for this condition.
"Currently we are focusing on Premature Ovarian Failure
as an initial clinical indication" Said Timothy Warbington, President and CEO of Creative Medical Technology Holdings. "Initial
success in this indication will allow us to address aspects of the wider infertility market, which is estimated to reach over 20
billion dollars annually."
Creative Medical Technologies, the Company's wholly owned
subsidiary, is currently running a clinical trial utilizing its patented CAVERSTEMTM approach for treatment of erectile
dysfunction using bone marrow stem cells. The Company intends to apply know-how and practical experiences learned from the ongoing
trial to its efforts in the area of Premature Ovarian Failure.
"Our vision is the creation of a series of regenerative
medicine based products that cover the continuum of human fertility from sexual dysfunction to initiation and maintenance of successful
pregnancy," said Dr. Thomas Ichim, Board Member of the Company. "This strategy can be seen from our initial issued
patent on erectile dysfunction, to our intellectual property on female sexual dysfunction, our in-licensed male infertility IP,
our data on recurrent spontaneous abortions, and now with the recent patent application on female infertility."
About Creative Medical Technology Holdings
Creative Medical Technology Holdings, Inc. is a clinical stage
biotechnology company currently trading on the OTCQB under the ticker symbol CELZ. For further information about the company go
to creativemedicaltechnology.com.
Forward-Looking Statements
OTC Markets has not reviewed and does not accept responsibility
for the adequacy or accuracy of this release. This news release may contain forward-looking statements including but not limited
to comments regarding the timing and content of upcoming clinical trials, marketing efforts, funding, etc. Forward-looking statements
address future events and conditions and, therefore, involve inherent risks and uncertainties. Actual results may differ materially
from those currently anticipated in such statements. See the periodic and other reports filed by Creative Medical Technology Holdings,
Inc. with the Securities and Exchange Commission and available on the Commission's website at www.sec.gov.
Contact:
Creative Medical Technology Holdings, Inc.
Timothy Warbington, CEO & President
(602) 680-7439
SOURCE Creative Medical Technology Holdings, Inc.
Last updated: Aug 24, 2016