Celcuity Reports Fourth Quarter and Full Year 2017 Financial Results Minneapolis, Minnesota

Celcuity Reports Fourth Quarter and Full

Year 2017 Financial Results

Minneapolis, Minnesota-March 15, 2018-Celcuity

Inc. (Nasdaq: CELC) a functional cellular analysis company that is discovering new cancer subtypes and commercializing diagnostic

tests designed to significantly improve clinical outcomes of cancer patients treated with targeted therapies, announced financial

results for the fourth quarter and year ended December 31, 2017. Unless otherwise stated, all comparisons are for the fourth quarter

and year ended December 31, 2017, compared to the fourth quarter and year ended December 31, 2016.

Celcuity reported a net loss of $1.7 million, or $0.17 per share,

for the fourth quarter of 2017, compared to a net loss of $0.9 million, or $0.14 per share, for the fourth quarter of 2016. Net

loss for fiscal year 2017 was $6.3 million, or $0.84 per share, compared to $3.3 million, or $0.52 per share, for fiscal year 2016.

Non-GAAP adjusted net loss was $1.4 million, or $0.14 per share,

for the fourth quarter of 2017, compared to non-GAAP adjusted net loss of $0.8 million, or $0.13 per share, for the fourth quarter

of 2016. Non-GAAP adjusted net loss for fiscal year 2017 was $4.9 million, or $0.66 per share, compared to non-GAAP adjusted net

loss of $3.1 million, or $0.49 per share, for fiscal year 2016. Non-GAAP adjusted net loss excludes stock-based compensation expense

and non-cash interest expenses. Because these items have no impact on the cash position of the Company, management

believes Non-GAAP adjusted net loss better enables Celcuity to focus on cash used in operations. For a reconciliation of

financial measures in accordance with generally accepted accounting principles of the United States (GAAP) to non-GAAP financial

measures in this release, please see the financial tables at the end of this news release.

Net cash used in operating activities for the fourth quarter

of 2017 was $1.1 million. Net cash used in operating activities for fiscal year 2017 was $4.9 million. At December 31, 2017, Celcuity

had cash, cash equivalents and investments of $31.4 million, compared to cash, cash equivalents, and investments of $5.9 million

at December 31, 2016.

"With the completion of our initial public offering, expansion

of our R&D team, and the initiation of our clinical collaboration with the NSABP Foundation and Genentech, Celcuity made tremendous

progress in 2017," said Chairman and Chief Executive Officer, Brian Sullivan. "With our expanded R&D team in place,

we began work on our next generation of cell signaling function tests to diagnose new cancer sub-types. Additionally, we presented

results of several pre-clinical studies at major conferences, including the American Society of Clinical Oncology Annual Meeting,

the Miami Breast Cancer Conference, and the San Antonio Breast Cancer Symposium.

Mr. Sullivan added, "During the fourth quarter, we continued

to lay the groundwork to activate the clinical trial we are fielding in collaboration with the NSABP Foundation and Genentech.

This clinical trial, Functional Analysis of live Cell signaling Transduction 1, or FACT 1, will evaluate

the efficacy of two of Genentech's HER2 drugs, Herceptin and Perjeta , in HER2-negative breast cancer patients selected

by our CELx HER2 Signaling Function test. We expect interim results from this trial in late 2018 and final results six to nine

"Our strategy is to develop diagnostics that identify

new cancer sub-types and to seek collaborations with pharmaceutical companies, which can vary in scope. Our efforts have resulted

in Celcuity recently being selected by NSABP and Puma Biotechnology to evaluate tissue samples from a Phase II study evaluating

Puma Biotechnology's pan-HER inhibitor, Nerlynx, Genentech's HER2 antibody, Herceptin, and Bristol-Myers Squibb's

drug, EGFR inhibitor, Erbitux, in metastatic colorectal cancer patients. This 35-patient study is expected to be completed in late

2020. Unlike our current trial with NSABP and Genentech, Celcuity's test will be used solely to evaluate patient samples

after they have been enrolled in this trial. We expect our CELx test will provide critical insight after the trial is completed

about the patient characteristics most correlative to drug response.

"Finally, as we look ahead to the end of 2018, we anticipate

completing development of new cell signaling function tests for breast cancer and two additional tumor types. We anticipate these

new tests will create opportunities for pharmaceutical companies to obtain new drug indications to treat patients who have the

cancer sub-types our tests diagnose. We also hope to initiate an additional clinical collaboration with a pharmaceutical company

Operating expenses were $1.8 million for the fourth quarter

of 2017, compared to $0.9 million for the fourth quarter of 2016. Operating expenses for fiscal year 2017 were $6.0 million, compared

to $3.3 million for fiscal year 2016.

Research and Development Expenses:

Research and development (R&D) expenses were $1.4 million

for the fourth quarter of 2017, compared to $0.8 million for the fourth quarter of 2016. R&D expenses for fiscal year 2017

were $5.0 million, compared to $3.1 million for fiscal year 2016. The approximately $1.9 million increase during fiscal year 2017,

compared to fiscal year 2016, resulted primarily from an increase in employee-related expenses, including approximately $0.4 million

of stock-based compensation, to support development of the CELx platform. Legal expenses related to patent costs, start-up clinical

trial costs, and business development activities also contributed to the increase.

General and Administrative Expenses:

General and administrative (G&A) expenses were $0.4 million

for the fourth quarter of 2017, compared to $0.1 million for the fourth quarter of 2016. G&A expenses for fiscal year 2017

were $1.0 million, compared to $0.3 million for fiscal year 2016. The approximately $0.7 million increase during fiscal year 2017

compared to fiscal year 2016 resulted primarily from increases in expenses associated with being a public company, such as professional

accounting and audit fees and director and officer insurance, and compensation-related expenses, including approximately $0.3 million

of stock-based compensation.

Management will host a teleconference call at 4:30 PM Eastern

Time today to discuss the results. Anyone interested in participating should dial 1-888-632-3389 referencing confirmation code

"Celcuity" (23528489). Participants are asked to dial in 5 to 10 minutes prior to the start of the call and inform

the operator you would like to join the "Celcuity Conference Call."

Celcuity Inc. is a cellular analysis

company that is discovering new cancer sub-types and commercializing diagnostic tests designed to significantly improve the clinical

outcomes of cancer patients treated with targeted therapies. Celcuity's proprietary CELx diagnostic platform uses a

patient's living tumor cells to identify the specific abnormal cellular activity driving a patient's cancer and the

targeted therapy that can best treat that patient's disease. Celcuity is headquartered in Minneapolis, MN. Further information

about Celcuity can be found at www.celcuity.com.

Forward-Looking Statements

This press release contains statements

that constitute "forward-looking statements." In some cases, you can identify forward-looking statements by terminology

such as "may," "should," "expects," "plans," "anticipates," "believes,"

"estimates," "predicts," "potential," "intends" or "continue," and

other similar expressions that are predictions of or indicate future events and future trends, or the negative of these terms or

other comparable terminology. Forward looking statements in this release include, without limitation, the anticipated benefits

to the clinical outcomes of cancer patients, expectations with respect to commercializing diagnostic tests, expectations with respect

to use of cash, the discovery of additional cancer sub-types, the development of additional CELx Signaling Function tests and planned

collaboration with pharmaceutical companies, expectations regarding the outcome of the clinical trial with NSABP Foundation and

Genentech, expectations with respect to our future collaboration with NSABP Foundation and Puma Biotechnology, anticipated

benefits that our tests may provide pharmaceutical companies and plans to expand research and development

and operational processes. Forward-looking statements are subject to numerous conditions, many of which are beyond the control

of Celcuity, which include, but are not limited to, those set forth in the Risk Factors section of Celcuity's Prospectus,

dated September 19, 2017, filed with the Securities and Exchange Commission on September 20, 2017 pursuant to Rule 424(b)(4) under

the Securities Act of 1933, as amended. Readers are cautioned not to place undue reliance on these

forward-looking statements, which speak only as of the date hereof. Celcuity undertakes no obligation to update these statements

for revisions or changes after the date of this release, except as required by law.

Brian Sullivan, bsullivan@celcuity.com

Vicky Hahne, vhahne@celcuity.com

Cautionary Statement

Regarding Non-GAAP Financial Measures

This news release contains references to non-GAAP

adjusted net loss and non-GAAP adjusted net loss per share. Management believes these non-GAAP financial measures are useful supplemental