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Celcuity Announces Issuance of New Patent for Gedatolisib that Extends Patent Exclusivity into 2042

Key Takeaway: Celcuity Inc. announced the issuance of a U.S. patent covering the clinical dosing regimen for its drug candidate gedatolisib, extending patent exclusivity in the U.S. until 2042. This enhances Celcuity's intellectual property portfolio, positioning the company favorably for the future. The company expects to announce topline clinical trial data for the PIK3CA cohorts in late 2025. However, there are risks related to potential challenges to the patent's validity and the timeline of the clinical trial outcomes.

Market Sentiment Analysis

POSITIVE FACTORS

  • Issuance of a new patent extends exclusivity for gedatolisib into 2042.
  • Strengthens Celcuity's intellectual property portfolio significantly.
  • Anticipation of upcoming clinical trial data could boost investor confidence.

CONCERNS & RISKS

  • Potential challenges from generics or other parties regarding patent validity.
  • Possibility of delays in the VIKTORIA-1 clinical trial results.

Full Press Release Details

MINNEAPOLIS, July 14, 2025 (GLOBE NEWSWIRE) -- Celcuity Inc. (Nasdaq: CELC), a clinical-stage biotechnology company pursuing development of targeted therapies for oncology, today announced the issuance of U.S. Patent No. 12,350,276 covering the clinical dosing regimen for its lead drug candidate, gedatolisib, in ER+/HER2- breast cancer patients. The patent extends Celcuity’s patent exclusivity in the U.S. into 2042.
“This dosing regimen patent reflects our commitment to enhancing our intellectual property portfolio,” said Brian Sullivan, CEO and Co-Founder of Celcuity. “With patent exclusivity for gedatolisib now extended into 2042, we expect to have a long runway to optimize development of gedatolisib.”
The United States Patent and Trademark Office previously issued five U.S. patents directed to gedatolisib’s composition of matter, four U.S. patents directed to various formulations comprising gedatolisib, and three U.S. patents directed to methods of using gedatolisib. The worldwide gedatolisib-related patent portfolio now comprises 13 granted gedatolisib-related patents in the U.S. and 290 patents granted in foreign jurisdictions.
Celcuity expects to announce topline data for the PIK3CA wild-type cohort of the VIKTORIA-1 clinical trial in the third quarter of 2025 and to report topline data for the PIK3CA mutant cohort in the fourth quarter of 2025.
Forward-Looking Statements
This press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995, including statements relating to patent scope and length of protection and the anticipated timing of topline data from the VIKTORIA-1 clinical trial. Words such as, but not limited to, “look forward to,” “believe,” “expect,” “anticipate,” “estimate,” “intend,” "confidence," "encouraged," “potential,” “plan,” “targets,” “likely,” “may,” “will,” “would,” “should” and “could,” and similar expressions or words identify forward-looking statements. The forward-looking statements included in this press release are based on management's current expectations and beliefs which are subject to a number of risks, uncertainties and factors, including that generics or others could challenge the validity of the gedatolisib patents, Celcuity may not be able to enforce the patents, there could be patent-related litigation or the progress of the VIKTORIA-1 clinical trial may be delayed. In addition, all forward-looking statements are subject to other risks detailed in our Annual Report on Form 10-K for the year ended December 31, 2024. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are qualified in their entirety by these cautionary statements, and we undertake no obligation to revise or update this news release to reflect events or circumstances after the date hereof.
View source version of release on GlobeNewswire.com
Brian Sullivan, bsullivan@celcuity.com
Vicky Hahne, vhahne@celcuity.com

Frequently Asked Questions

What is U.S. Patent No. 12,350,276 for?

The patent covers the dosing regimen for gedatolisib in ER+/HER2- breast cancer patients.

How long is patent exclusivity for gedatolisib extended?

Patent exclusivity for gedatolisib is extended until 2042.

How many patents does Celcuity hold for gedatolisib?

Celcuity's gedatolisib patent portfolio includes 13 U.S. patents and 290 foreign patents.

When will topline data for VIKTORIA-1 be announced?

Topline data for the PIK3CA wild-type cohort is expected in Q3 2025.

What risks are associated with Celcuity's forward-looking statements?

Risks include challenges to patent validity and potential delays in clinical trial progress.

Last updated: Jul 14, 2025